| MicroRNA在心血管疾病方面的研究现状及应用前景 |
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| 引用本文： | 薛嘉嘉,高亚彪,程志奇,田美慧,肖莹,贾宇晴,曹志鹏,朱宝利.MicroRNA在心血管疾病方面的研究现状及应用前景[J].中国法医学杂志,2017(5):488-491. |
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| 作者姓名： | 薛嘉嘉 高亚彪 程志奇 田美慧 肖莹 贾宇晴 曹志鹏 朱宝利 |
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| 作者单位： | 中国医科大学法医学院,辽宁 沈阳,110122 |
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| 基金项目： | 国家自然科学基金资助项目(81273343) |
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| 摘 要： | MicroRNA(miRNA或mi R)是一类21~25nt大小的高度保守的内源性单链非编码RNA,在生物体内广泛存在。近年来,在临床研究中与心血管疾病相关的mi RNA不断得以证实,但其在法医学鉴定方面的研究尚未有报道。本文就mi RNA的研究进展及其在心血管疾病中的应用,以及在心源性猝死法医学鉴定中的应用前景进行综述。
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| 关 键 词： | 法医病理学 microRNA 心血管疾病 |
The research and application of microRNA in human cardiovascular disease and forensic science |
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| Xue Jiajia,Gao Yabiao,Cheng Zhiqi,Tian Meihui,Xiao Ying,Jia Yuqing,Cao Zhipeng,Zhu Baoli.The research and application of microRNA in human cardiovascular disease and forensic science[J].Chinese Journal of Forensic Medicine,2017(5):488-491. |
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| Authors: | Xue Jiajia Gao Yabiao Cheng Zhiqi Tian Meihui Xiao Ying Jia Yuqing Cao Zhipeng Zhu Baoli |
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| Abstract: | MicroRNA (miRNA or miR) is a class of highly conserved endogenous non-coding RNA of 21~25nt, which is widely existed in organisms. Currently, miRNA has been proven to be associated with cardiovascular diseases in clinical research, but it has not been reported in the field of forensic medicine. This paper highlights recent findings about miRNA and its application in cardiovascular diseases, and the application aspect of miRNA in sudden cardiac death in forensic science. |
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| Keywords: | forensic pathology microRNA cardiovascular diseases |
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