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桑菊饮加减联合阿奇霉素治疗小儿肺炎支原体感染风热咳嗽临床观察
作者姓名:张建文  项李娥  桂金贵  徐朝晖  费文君  尚莉丽
作者单位:安徽中医药大学,安徽 合肥,230012;安徽中医药大学第一附属医院儿科,安徽 合肥,230031
摘    要:目的 观察桑菊饮加减联合阿奇霉素治疗小儿肺炎支原体感染风热咳嗽的临床疗效。方法 将60例肺炎支原体感染风热咳嗽患儿随机分为对照组和治疗组,每组30例,对照组给予阿奇霉素治疗,治疗组在对照组治疗基础上加用桑菊饮加减。观察两组患儿体征改善时间及临床疗效。结果 与对照组比较,治疗组平均退热时间、啰音消失时间以及咳嗽缓解时间均显著缩短,差异有统计学意义(P<0.05)。两组临床疗效的分布比较,差异有统计学意义(P<0.05),治疗组临床疗效优于对照组。结论 桑菊饮加减联合阿奇霉素治疗小儿肺炎支原体感染风热咳嗽疗效确切。

关 键 词:肺炎支原体  风热咳嗽  桑菊饮  阿奇霉素

Clinical Effect of Modified Sangju Decoction Combined with Azithromycin in Treatment of Children with Wind-heat Cough Caused by Mycoplasma pneumoniae Infection
Institution:1.Anhui University of Chinese Medicine, Anhui Hefei 230012, China; 2. Department of Pediatrics, The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui Hefei 230031, China
Abstract:Objective To investigate the clinical effect of traditional Chinese medicine modified Sangju Decoction combined with azithromycin in the treatment of children with wind-heat cough caused by Mycoplasma pneumoniae infection. Methods A total of 60 children with wind-heat cough caused by Mycoplasma pneumoniae infection were randomly divided into control group and treatment group, with 30 children in each group. The children in the control group were given azithromycin, and those in the treatment group were given modified Sangju Decoction combined with azithromycin. The two groups were observed in terms of the time to the improvement in signs and clinical outcome. Results Compared with the control group, the treatment group had significantly shorter mean fever clearance time, time to the disappearance of rales, and time to the relief of cough (P<0.05). The treatment group had significantly better clinical outcomes than the control group (P<0.05). Conclusion Modified Sangju Decoction combined with azithromycin has a good clinical effect in the treatment of children with wind-heat cough caused by Mycoplasma pneumoniae infection.
Keywords:Mycoplasma pneumoniae  Wind-heat cough  Sangju Decoction  Azithromycin
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