基于经络平衡的电导法经络测量分析方法对慢性肾病的诊断价值研究

目的 基于经络平衡理论，探究电导法经络测量值的分析方法，考察其对慢性肾病的诊断价值。方法 纳入健康人群82例和慢性肾病人群222例，采用电导法测量手足井穴和原穴的电阻值，分别计算原穴阴阳比值、井穴阴阳比值、原穴手足比值、井穴手足比值、原穴左右比值、井穴左右比值，采用接收者工作特征（receiver operating characteristic, ROC）曲线考察两组差异具有统计学意义的比值对慢性肾病的诊断价值。结果 两组人群在井穴阴阳比值、原穴手足比值方面比较，差异具有统计学意义（P<0.05）。ROC曲线显示井穴阴阳比值的曲线下面积（area under curve, AUC）为0.618，95% CI为［0.537，0.699］（P<0.05），原穴手足比值的AUC为0.727，95% CI为［0.655，0.800］（P<0.01）。井穴阴阳比值的最优切点是1.16，灵敏度为0.64，特异度为0.52，原穴手足比值最优切点是1.04，灵敏度为0.68，特异度为0.72。结论 慢性肾病患者的经络平衡处于阴盛阳衰、上盛下衰状态，基于经络平衡的电导法经络测量分析方法具有较好的临床诊断效能。

Diagnostic Value of Meridian Measurement by Conductometry Based on Meridian Balance for Chronic Kidney Disease

Objective To study the meridian measurement by conductometry based on meridian balance theory and investigate its diagnostic value for chronic kidney disease (CKD). Methods Eighty-two healthy persons and 222 CKD patients were recruited. The resistance values of well points and source points of the hands and feet were measured by conductometry, and the yin-yang ratios, hand-foot ratios, and left-right ratios of source points and well points were calculated. The receiver operating characteristic (ROC) curve was used to investigate the diagnostic values of the ratios that showed significant differences between the two groups for CKD. Results There were significant differences in the yin-yang ratio of well point and hand-foot ratio of source point between the two groups (P<0.05). ROC curve analysis showed that the area under the ROC curve (AUC) of the yin-yang ratio of well point was 0.618 (95% CI: 0.537-0.699) (P<0.05), and the AUC of the hand-foot ratio of source point was 0.727 (95% CI: 0.655-0.800) (P<0.01). The optimal cut-off point for the yin-yang ratio of well point was 1.16, with a sensitivity of 0.64 and a specificity of 0.52. The optimal cut-off point for the hand-foot ratio of source point was 1.04, with a sensitivity of 0.68 and a specificity of 0.72. Conclusion CKD patients are in the state of yin excess and yang deficiency and the state of upper excess and lower deficiency. Meridian measurement by conductometry based on meridian balance has a good diagnostic value for CKD.