| 11个Y—STR基因座遗传多态性研究 |
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| 引用本文： | 孙宏钰,刘秋玲,童大跃,孙彦宾,陈勇.11个Y—STR基因座遗传多态性研究[J].中国法医学杂志,2002,17(5):267-269. |
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| 作者姓名： | 孙宏钰 刘秋玲 童大跃 孙彦宾 陈勇 |
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| 作者单位： | 中山大学中山医学院法医物证学教研室,广东,广州,510089 |
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| 摘 要： | 目的 调查11个Y染色体STR基因座的遗传多态性。方法 利用PCR扩增和聚丙烯酰胺凝胶电泳技术对广州地区汉族群体无关男性血样进行11个Y—STR基因座的分型。结果 11个Y—STR基因座在广州地区汉族群体分别发现3～5个等位基因,GD值最低为0.3037(DYS434),最高为0.8455(DYS390)。结论 11个Y—STR基因座在广州地区汉族群体均具有较高的遗传多态性,可应用于法科学个体识别和亲子鉴定。
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| 关 键 词： | 法科学 短串联重复序列(STR) Y染色体 遗传多态性 |
| 文章编号： | 1001-5728(2002)05-0267-03 |
| 修稿时间： | 2002年5月1日 |
A study of genetic polymorphisms of 11 Y chromosome specific STR loci |
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| STR loci /SUN Hongyu,LIU Qiuling,TONGDayue,et al..A study of genetic polymorphisms of 11 Y chromosome specific STR loci[J].Chinese Journal of Forensic Medicine,2002,17(5):267-269. |
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| Authors: | STR loci /SUN Hongyu LIU Qiuling TONGDayue |
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| Institution: | STR loci /SUN Hongyu,LIU Qiuling,TONGDayue,et al. / Department of Forensic Biology,Zhongshan Medical College,Zhongshan University,Guangzhou 510089 |
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| Abstract: | Objective To study the genetic polymorphisms of 11 Y chromosome specific STR loci in Guangzhou Han population. Method The DNA extracted from blood samples of unrelated individuals in Han population living in Guangzhou were amplified by PCR. The PCR products were analyzed by using PAGE. Results 3-5 alleles were detected in 11 Y - STR loci respectively in Han population in Guangzhou. The minimum GD value was 0.3037 (DYS434), while the maximum GD value was 0.8455 (DYS390) . Conclusion The 11 Y - specific STR loci are highly polymorphic and are suitable for personal identification and paternity testing. |
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| Keywords: | Forensic science Short tandem repeat (STR) Y chromosome Genetic polymorphism |
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