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Death from Nitrous Oxide
Authors:Björn Bäckström MD  Bengt Johansson MD  PhD  Anders Eriksson MD  PhD
Institution:1. Department of Forensic Medicine, National Board of Forensic Medicine, PO Box 7616, SE-907 12 Umeå, Sweden

Section 2. of Forensic Medicine, Department of Community Medicine and Rehabilitation, Umeå University, PO Box 7616, SE-907 12 Umeå, Sweden

Additional information and reprint requests:

Björn Bäckström, M.D.

Department of Forensic Medicine

National Board of Forensic Medicine

PO Box 7616

SE-907 12 Umeå

Sweden

E-mail: bjorn.backstrom@rmv.se;3. Department of Public Health and Clinical Medicine, Norrlands Universitetssjukhus SE-901 87, Umeå, Sweden;4. Section 5. of Forensic Medicine, Department of Community Medicine and Rehabilitation, Umeå University, PO Box 7616, SE-907 12 Umeå, Sweden

Abstract:Nitrous oxide is an inflammable gas that gives no smell or taste. It has a history of abuse as long as its clinical use, and deaths, although rare, have been reported. We describe two cases of accidental deaths related to voluntary inhalation of nitrous oxide, both found dead with a gas mask covering the face. In an attempt to find an explanation to why the victims did not react properly to oncoming hypoxia, we performed experiments where a test person was allowed to breath in a closed system, with or without nitrous oxide added. Vital signs and gas concentrations as well as subjective symptoms were recorded. The experiments indicated that the explanation to the fact that neither of the descendents had reacted to oncoming hypoxia and hypercapnia was due to the inhalation of nitrous oxide. This study raises the question whether nitrous oxide really should be easily, commercially available.
Keywords:forensic science  nitrous oxide  abuse  hypoxic asphyxia  death  restrictions
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