Hair analysis to document non-fatal pesticide intoxication cases |
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Authors: | Dulaurent S Gaulier J M Baudel J L Fardet L Maury E Lachâtre G |
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Institution: | Department of Pharmacology and Toxicology, University Hospital, 2 Avenue Martin Luther King, 87025 Limoges, France. sylvain.dulaurent@unilim.fr |
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Abstract: | We reported two non-fatal cases of intoxication with pesticides namely alachlor and carbofuran. Hair stand samples were collected from two men approximately 1 year after alachlor intoxication for case 1, and 14 days after the last exposure for case 2. Hair analysis was performed using a liquid chromatography-tandem mass spectrometry method. In case 1, alachlor was detected in the 5 analysed hair segments (concentrations between 12 and 136 pg/mg) and its metabolites were not detected. In case 2, carbofuran and its main metabolite (3-hydroxycarbofuran) were detected in the hair strand (global analysis) at the concentrations of 207 and 164 pg/mg, respectively. However, additional data are required in order to interpret such results. |
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Keywords: | Hair analysis Pesticides Alachlor Carbofuran Liquid chromatography-tandem mass spectrometry |
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