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| 家兔非热低压电击伤血清LDH和HBDH活性的动态变化 | |
| 引用本文： | 步建衡,靳彦奎,谷建平.家兔非热低压电击伤血清LDH和HBDH活性的动态变化[J].中国法医学杂志,2009,24(2):87-89. |
| 作者姓名： | 步建衡 靳彦奎 谷建平 |
| 作者单位： | 1. 河北省公安厅,河北,石家庄,050051 2. 石家庄市人民检察院,河北,石家庄,050090 3. 河北省人民检察院,河北,石家庄,050000 |
| 摘 要： | 目的研究家兔非热低压电击伤后不同时相乳酸脱氢酶（lactate dehydrogenase，LDH）和羟丁酸脱氧酶（hydroxybutyrate dehydrogenase，HBDH）活性的变化，为临床和法医学非热电击伤提供诊断依据。方法健康新西兰大白兔40只，随机分为对照组和电击伤后7个时间点的实验组，每组5只。实验各组家兔用220V 50Hz交流电电击2S后自由进食，按照预定时间点麻醉后抽取心室血5mL，使用自动生化仪（type Selectra-2）测定血清LDH、HBDH酶活性。对照组家兔不电击，其他处理同实验组。结果实验组家兔目标血清酶活性发生了动态变化，有一定规律性，LDH活性在电击后4h，12h，1d，2d，3d明显升高（4h，12h，1dP〈0．01；2d，3dP〈0．05）；HBDH活性在电击后2d、3d明显升高（P〈0．05）；HBDH／LDH比值在2h、4h、12h与对照组比较显著降低（P〈0．01）。结论动态监测LDH、HBDH活性，可为非热电击损伤的诊断、损伤时间推断提供理论依据。 |
| 关 键 词： | 法医病理学 电击伤 乳酸脱氢酶 羟丁酸脱氢酶 |
An unstatic experiments of LDH and HBDH activities in rabbit serum after electrical injury |
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| BU Jianheng,JIN Yankui,GU Jianping.An unstatic experiments of LDH and HBDH activities in rabbit serum after electrical injury[J].Chinese Journal of Forensic Medicine,2009,24(2):87-89. | |
| Authors: | BU Jianheng JIN Yankui GU Jianping |
| Institution: | BU Jianheng, JIN Yankui, GU Jianping(1. Public Security Department of Hebei Provincial, Shijiazhuang 050051, China; 2. Shijiazhuang municipal People＇s Procuratorate, Hebei 050000, China; 3. Hebei People＇s Procuratorate , Shijiazhuang 050000, China) |
| Abstract: | Objective Observing the phase changes of lactate dehydrogenase (LDH) and hydroxybutyrate dehydrogenase (HBDH) activities, so as to provide a basis of diagnosis of electric injury for clinic and forensic medicine cases. Methods The experimental animals were composed of 40 Healthy New Zealand rabbits and divided into eight groups with 5 rabbits for each: one control group and seven electric-shocked groups treated in different time points (0h, 2h, 4h, 12h, 1d, 2d, 3d) with electric injury. 5 mL of ventricle bl... |
| Keywords: | forensic pathology electrical injury LDH HBDH |
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