端粒DNA在法医学年龄推断中的应用

法医学中年龄推断的常用方法是对齿龄和骨龄进行推断,但这二种方法都受地理环境、营养状况、生活习惯、民族等因素的影响,尤其对成年人而言准确性会下降。随着对端粒研究的不断深入,已证实端粒DNA长度可反映细胞的分裂程度,代表细胞的生长寿命并与供体年龄有负相关性,因此测定端粒DNA长度有望成为法医学推断年龄有价值的新方法。

The application of telomere DNA in age estimation of forensic medicine

Estimating tooth age and skeletal age are the two primary methods in age estimation of forensic medicine. But they are often impacted with geographical environment, nutrition, habitation and ethenologic differences,so the accuracy will be reduced, especially to the adult. With the study of telomere, it is certain that the length of the telomere DNA can reflect the cell division and represent the cell lifespan,and it has some pertinence to the age of the donor, so to measure the length of telomere DNA is a new and valuable method for age estimation in the forensic medicine.