| 月经血鉴定与基质金属蛋白酶-11 |
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| 作者姓名： | Zheng J Lu HL Chen S |
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| 作者单位： | 中山大学基础医学院法医物证学教研室,广东,广州,510080 |
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| 基金项目： | 国家自然科学基金资助项目(30471933) |
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| 摘 要： | 月经血鉴定是法医血痕检验的内容之一。本文就月经血鉴定的几种经典方法进行回顾,并分析其应用局限性。基质金属蛋白酶-11是一种能降解细胞外基质的水解蛋白酶,有研究提示基质金属蛋白酶-11以其在月经血中表达的特异性和检测方法的灵敏性有可能成为对月经血鉴定的新一代标志物。本文对基质金属蛋白酶-11的结构、功能、在月经血鉴定中的应用及展望进行综述。
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| 关 键 词： | 法医学 月经血 基质金属蛋白酶-11 |
| 文章编号： | 1004-5619(2006)01-00S1-03 |
| 修稿时间： | 2005年4月11日 |
Menstrual blood identification and matrix metalloproteinase-11 |
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| Zheng J,Lu HL,Chen S.Menstrual blood identification and matrix metalloproteinase-11[J].Journal of Forensic Medicine,2006,22(1):I0001-I0003. |
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| Authors: | Zheng Jing Lu Hui-ling Chen Sen |
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| Institution: | Department of Forensic Biology, Basis Medical College, Sun Yat-sen University, Guangzhou 510080, China. zk-wzj@yahoo.com.cn |
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| Abstract: | The identification of menstrual blood belongs to the forensic examination of bloodstains. The traditional methods for detecting menstrual blood were reviewed and their obstacles in forensic application were discussed. Matrix metalloproteinase-11 is a kind of protease which degrades the extracellular matrix. Some researches had indicated that matrix metalloproteinase-11 might be a new marker for specifically and sensitively detecting menstrual blood. The structure, function of matrix metalloproteinase-11 and its application in menstrual blood identification were reviewed. |
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| Keywords: | forensic science menstrual blood matrix metalloproteinase-11 |
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