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活力晶对大鼠学习记忆影响的研究
作者姓名:杨玉福  吕雄文  马传庚
作者单位:安徽医科大学药理学教研室,安徽合肥230032
摘    要:目的:观察活力晶对正常成年大鼠学习记忆的影响。方法:采用跳台实验和免疫组织化学ABC法。结果:服药组海马生长抑素(SS)、精氨酸加压素(AVP)在各部表达增强;跳台实验的逃避时间(EL)缩短,大鼠从台上跳到台下的潜伏期(SDL)延长。结论:活力晶具有促进记忆蛋白的表达而增强大鼠记忆能力的作用。

关 键 词:活力晶  生长抑素  精氨酸加压素  学习记忆  中药  药理
修稿时间:2002/5/21 0:00:00

EFFECT OF HUOLIJING GRANULES ON ABILITIES OF LEARNING AND MEMORY IN NORMAL ADULT RATS
Abstract:Objective:To observe the effects of Huolijing (HLJ) granules on the abilities of learning and memory in normal adult rats. Method: Springing to platform test and immunohistochemical ABC were employed. Result: Somatostatin (SS), arginine vasopressin hormone (AVP) had a higher expression in the experimental group than those in the control group.Spinging to platform test showed that escape latency(EL) was shorter,while step down latency(SDL) was significantly longer.Conclusion:HLJ granules improve memory ability by facilitating the expression of memory protein.
Keywords:Huolijing granules  Somatostatin  Arginine vasopressin hormone  Learning and memory
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