紫参颗粒镇静催眠作用的实验研究

目的：观察紫参颗粒的镇静催眠作用。方法：采用自主活动实验及戊巴比妥钠催眠实验。结果：紫参颗粒能减少小鼠自主活动次数，明显增加睡眠小鼠的只数，延长小鼠的睡眠时间，与阴性对照组比较，差异有显性。结论：紫参颗粒具有镇静催眠作用。

Sedative and Hypnotic Effect of Zishen Granule in Mice

Objective:To observe sedative and hypnotic effects of Zishen Granule in mice. Method:Tests of independence activity and sodium pentobarbital-induced sleep were employed.The effects of Zishen Granule on independence activities, under threshold dosage of sodium pentobarbital-induced hypnosis and threshold dosage of sodium pentobarbital-induced sleep time of mice were estimated.Result: Zishen Granule could reduce the number of independence activities of mice, obviously increase the number of mice falling asleep and sleep time, compared with those of negative group, there was significant difference. Conclusion: Zishen granule has sedative and hypnotic effects.