| 脾虚患者SIL-2R与淋巴细胞增殖活性相关性研究 |
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| 作者姓名： | 章梅 夏天 张仲海 行利 徐重明 |
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| 作者单位： | 中国人民解放军第四军医大学西京医院!西安710032 |
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| 摘 要： | 目的：研究脾虚患者ＳＩＬ ２Ｒ 含量与淋巴细胞增殖活性关系。方法：采用３ Ｈ ＴｄＲ 掺入法，ＥＬＩＳＡ 双抗体夹心法测定脾虚患者、正常人外周血淋巴细胞增殖活性，血浆及ＰＨＡ 诱导的７２ｈ淋巴细胞培养上清ＳＩＬ ２Ｒ 含量。结果：脾虚患者外周血淋巴细胞对ＰＨＡ 诱导的增殖反应较正常人明显下降（ Ｐ＜ ０ ．０１） ，淋巴细胞培养上清ＳＩＬ ２Ｒ含量显著低于正常组，其水平与淋巴细胞增殖反应量正相关（ Ｐ＜ ０ ．０１） ，但外周血ＳＩＬ ２Ｒ 含量显著地高于正常对照组（ Ｐ＜ ０ ．０１） 。结论：脾虚患者存在免疫功能紊乱
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| 关 键 词： | 淋巴细胞转化 SIL-2R 脾虚 |
STUDY OF SIL-2R AND LYMPHOCYTE PROLIFERATIVE ACTIVITY IN PATIENTS WITH SPLEEN ASTHENIA |
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| Authors: | Zhang Mei Xia Tian Zhang Zhonghai Hang Li Xu Chongmin |
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| Abstract: | Objetive:To study the SIL 2R and lymphocyte proliferative activity in patients with spleen asthenia.Method:By methods of H 3 TdR and ELISA,PBMC proliferative activity induced by PHA in patients with spleen asthenia and the normals and SIL 2R lymphocyte culture from PSA were determined respectively.Result:The results showed that the PBMC proliferative activity induced by PHA in PSA decreased significfantly than that in NA.The supernal SIL 2R of lymphocyte culture from PSA showed a lower expression than that from NA and it had a positive correlation.But the SIL 2R of peripheral blood is significantly higher than that in the normals.Conclusion:All these suggest that there be a immunologic disturbance in patients with spleen asthenia. |
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| Keywords: | SIL 2R Spleen asthenia Lymphocyte proliferative activity |
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