补肾益精法治疗远端肾小管酸中毒致低钾血症31例

目的 观察补肾益精法治疗远端肾小管酸中毒（distal renal tubular acidosis，dRTA）致低钾血症的疗效。方法 将62例dRTA患者随机分为观察组31例和对照组31例，对照组仅给予常规西医补钾治疗，观察组加用补肾益精中药进行综合治疗。比较两组的临床疗效及血清钾浓度的变化。结果 两组临床疗效的分布比较，差异具有统计学意义（P<0.05），观察组临床疗效显著优于对照组；随着治疗时间延长，两组血钾浓度均较前一时点显著升高（P<0.05）；治疗48 h和72 h后，观察组血钾浓度显著高于对照组（P<0.05）。结论 补肾益精法联合西医补钾治疗能提高dRTA致低钾血症患者血钾水平，提高临床疗效。

Efficacy of Kidney nourishing and Essence enriching Therapy in Treatment of Hypokalemia Induced by Distal Renal Tubular Acidosis: A Report of 31 Cases

Objective To observe the clinical efficacy of kidney nourishing and essence enriching therapy in the treatment of hypokalemia induced by distal renal tubular acidosis (dRTA). Methods Sixty two dRTA patients were randomly divided into observation group and control group, each with 31 patients. Patients in the control group received conventional Western medicine treatment (potassium supplementation), while those in the observation group were given comprehensive traditional Chinese medicine treatment (kidney nourishing and essence enriching therapy plus potassium supplementation). Then the treatment outcomes and serum potassium of the two groups were compared. Results There were significant differences in the distribution of clinical outcomes between the two groups (P<0.05); the observation group had a significantly better clinical outcome than the control group (P<0.05). The level of serum potassium at a later time point was significantly higher than that at the former one in both groups (P<0.05). After 48 and 72 hours of treatment, the level of serum potassium was significantly higher in the observation group than in the control group (P<0.05). Conclusion Kidney nourishing and essence enriching therapy combined with potassium supplementation can effectively increase the level of serum potassium in patients with hypokalemia induced by dRTA and has improved clinical efficacy.