电针大肠合穴下合穴配穴治疗腹泻型肠易激综合征疗效观察

目的 观察电针刺激大肠合穴下合穴配穴（曲池、上巨虚）对腹泻型肠易激综合征的临床疗效。方法 将60例腹泻型肠易激综合征患者，随机分为电针组和药物组，每组30例。其中电针组采用电针双侧曲池、上巨虚穴；药物组口服盐酸洛哌丁胺胶囊。各组于治疗前、治疗2周、治疗4周、治疗结束后4周随访时，分别记录每周排便次数、大便性状评分及每周正常排便天数，同时采用焦虑自评量表（self-rating anxiety scale，SAS）、抑郁自评量表（self-rating depression scale，SDS）评估患者的精神心理状态。结果 治疗前两组患者每周排便次数、大便性状评分、每周正常排便天数比较，差异均无统计学意义（P＞0.05）；两组患者治疗后每周排便次数、大便性状评分、每周正常排便天数与治疗前比较，差异具有统计学意义（P＜0.05），但两组间比较，差异无统计学意义（P＞0.05）。两组患者治疗结束后4周随访时，每周排便次数、大便性状评分、每周正常排便天数与治疗前比较，差异具有统计学意义（P＜0.05），但与治疗4周时比较，差异无统计学意义（P＞0.05）。两组患者治疗前后SAS、SDS评分比较，差异具有统计学意义（P＜0.05）；两组间比较，差异无统计学意义（P＞0.05）。结论 电针大肠合穴下合穴配穴治疗腹泻型肠易激综合征具有良好的临床疗效，其疗效与常规药物治疗效果相当，且其效应具有一定的持续性。

Clinical Effect of Electroacupuncture at Quchi and Shangjuxu in Treatment of Diarrhea-predominant Irritable Bowel Syndrome

Objective To investigate the clinical effect of electroacupuncture at Quchi and Shangjuxu in the treatment of diarrhea-predominant irritable bowel syndrome. Methods A total of 60 patients with diarrhea-predominant irritable bowel syndrome were randomly divided into electroacupuncture group and medication group, with 30 patients in each group. The patients in the electroacupuncture group were given electroacupuncture at Quchi and Shangjuxu on both sides, and those in the medication group were given oral loperamide hydrochloride capsules. The number of times of defecation each week, stool property score, and the number of days with normal defecation each week were recorded before treatment, at weeks 2 and 4 of treatment, and at 4 weeks after treatment, and the Self-Rating Depression Scale (SAS) and Self-Rating Depression Scale (SDS) were used to evaluate patients'' mental and psychological state. Results There were no significant differences in the number of times of defecation each week, stool property score, and number of days with normal defecation each week between the two groups before treatment (P>0.05); both groups had significant changes in these indices after treatment (P<0.05), but there were still no significant differences between the two groups (P>0.05). At 4 weeks after treatment, both groups had significant changes in the number of times of defecation each week, stool property score, and number of days with normal defecation each week (P<0.05), but there were no significant changes in these indices from week 4 of treatment to this time point (P>0.05). Both groups had significant changes in SAS and SDS scores after treatment (P<0.05), and there were no significant differences between the two groups (P>0.05). Conclusion Electroacupuncture at Quchi and Shangjuxu has a good clinical effect in the treatment of diarrhea-predominant irritable bowel syndrome, which is comparable to the clinical effect of routine medication, and such effect can last for a certain period of time.