| 图片再认ERP在重型颅脑损伤后记忆障碍鉴定的应用 |
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| 引用本文： | 刘子龙,吴静铭,刘良,陈晓瑞,赵小红,张玲莉,饶广勋,李海霞.图片再认ERP在重型颅脑损伤后记忆障碍鉴定的应用[J].中国法医学杂志,2009,24(2):92-95. |
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| 作者姓名： | 刘子龙 吴静铭 刘良 陈晓瑞 赵小红 张玲莉 饶广勋 李海霞 |
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| 作者单位： | 1. 华中科技大学同济医学院法医学系,湖北,武汉,430030
2. 同济医学院附属同济医院儿科,湖北,武汉,430030 |
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| 摘 要： | 目的探讨图片再认事件相关电位（ERP）对重型颅脑损伤（sTBI）后记忆障碍法医学鉴定的应用价值。方法采用韦氏记忆量表（WMS—RC）和Neuroscan ERP仪，对74例健康志愿者（对照组）及需评定精神伤残等级的29例重型颅脑损伤后记忆障碍者（sTBI组）进行记忆能力和图片再认ERP检测。结果sTBI组WMS-RC各分测验量表分及记忆商数（MQ）均值均明显低于对照组（P〈0．01）；完成ERP任务的反应时、正确率明显延长和降低（P〈0．01）。对照组在靶与非靶刺激呈现后170ms和500ms左右均可记录到潜伏期无显著性差异的二个正向波（P170和P500），但靶刺激诱发的P500波幅明显高于非靶刺激（P〈0．01）；sTBI组可记录到相似的ERP波形，但各成分的波幅、潜伏期均明显降低和延长（P〈0．01）。sTBI组P500潜伏期与WMS—RC的记图、再认、再生分测验量表分和MQ值均呈高度负相关（r=-0．73～-0．83，P〈0．01），而与伤残等级呈明显正相关（r=0．65，P〈0．01）。结论图片再认诱发的Psoo潜伏期与WMS-RC反映的短时记忆功能及鉴定的精神伤残等级明显相关，可为sTBI后记忆障碍的伤残鉴定提供一项较客观的神经电生理依据。
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| 关 键 词： | 法医临床学 重型颅脑损伤 记忆障碍 事件相关电位 图片再认 伤残等级 |
The application of ERP with picture recognition in expertise of memory disorder induced by severe traumatic brain injury |
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| LIU Zilong,WU Jingming,LIU Liang,CHEN Xiaorui,ZHAO Xiaohong,ZHANG Lingli,RAO Guangxun,LI Haixia.The application of ERP with picture recognition in expertise of memory disorder induced by severe traumatic brain injury[J].Chinese Journal of Forensic Medicine,2009,24(2):92-95. |
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| Authors: | LIU Zilong WU Jingming LIU Liang CHEN Xiaorui ZHAO Xiaohong ZHANG Lingli RAO Guangxun LI Haixia |
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| Institution: | LIU Zilong1,WU Jingming1,LIU Liang1,CHEN Xiaorui1,ZHAO Xiaohong1,ZHANG Lingli1,RAO Guangxun1,LI Haixia2 /1.Faculty of Forensic Medicine,Tongji Medical College of Huazhong University of Science , Technology,Wuhan 430030,China,2.Department of Pediatrics,Tongji Hospital,Tongji Medical College |
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| Abstract: | Objective To investigate the application value of event-related potentials(ERP) with picture recognition in expertise of memory disorder induced by severe traumatic brain injury (sTBI). Methods ERP were recorded in 29 patients with memory disorder induced by sTBI and 74 healthy controls, while they were asked to compare target and non-target pictures and judge whether it was target stimulus. Memory function was examined by the Chinese Wechsler memory scale revised (WMS-RC). Results The mean scale scores of ... |
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| Keywords: | forensic clinical medicine severe traumatic brain injury memory disorder eventrelated potentials picture recognition disability grade |
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