| 人线粒体DNA序列分析在法医学中的应用研究及其进展 |
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| 引用本文： | 钱海洪,胡义德.人线粒体DNA序列分析在法医学中的应用研究及其进展[J].中国法医学杂志,2006,21(2):97-98. |
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| 作者姓名： | 钱海洪 胡义德 |
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| 作者单位： | 第三军医大学新桥医院全军肿瘤中心,重庆,400037 |
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| 摘 要： | 综述人线粒体DNA(m tDNA)序列分析在法医学种属鉴别、个体识别,以及个体年龄推断中的应用研究及其进展,展望对m tDNA异质性的研究及建立人m tDNA数据库,并具有重要的法医学实践意义。
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| 关 键 词： | 法医物证学 线粒体DNA(mtDNA) 序列分析 |
| 文章编号： | 1001-5728(2006)02-0097-02 |
| 修稿时间： | 2004年10月28 |
The forensic application and study progress of human mitochondrial DNA sequence analysis |
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| QIAN Hai-hong,HU Yi-de.The forensic application and study progress of human mitochondrial DNA sequence analysis[J].Chinese Journal of Forensic Medicine,2006,21(2):97-98. |
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| Authors: | QIAN Hai-hong HU Yi-de |
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| Abstract: | his review article is aimed at discussing the forensic application and study progress of mtDNA sequence analysis.This analysis can be applied in species and individual identification,detection for minute and acaryotic materials and also in age estimation.The major problem in mtDNA sequence analysis is heteroplasmy of mtDNA.The major reason causing heteroplasmy of mtDNA is contamination of samples.Heteroplasmy of mtDNA can be decreased only if contamination of samples could be avoided.Set up database of mtDNA will definitely be helpful for forensic medicine services. |
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| Keywords: | Forensic biological evidence Mitochondrial DNA Sequence analysis |
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