| 利用Q-TOFLC/MS建立二级谱图数据库快速检测90种农药的初步研究 |
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| 引用本文： | 郭杰,许秋实,石辉丽,商金磊.利用Q-TOFLC/MS建立二级谱图数据库快速检测90种农药的初步研究[J].刑事技术,2013(4):41-45. |
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| 作者姓名： | 郭杰 许秋实 石辉丽 商金磊 |
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| 作者单位： | 1. 山东青岛市公安局刑警支队,266001
2. 福建泉州市公安局刑侦支队,362000 |
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| 摘 要： | 目的建立90种农药的数据库（含二级谱图）,以达到快速筛选检验该范围内的未知样品目的。方法优化一种Q-TOF LC/MS分析条件,将90种农药分别依次进行Q-TOF LC/MS-MS二级谱图分析,利用PCDL软件建立数据库。并同时实验了血样中10种不同浓度农药（100ng/mL、500ng/mL）的添加实验,对建库方法进行了验证。结果阳性识别率在80%以上。结论本方法简便灵敏、快速实用。
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| 关 键 词： | 二级谱图数据库 四极杆飞行时间串联液质 农药 快速筛选及确认 |
Determination of 90 kinds of pesticide in unknown samples by QTOF-LC/MS and MS/MS database |
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| Institution: | GUO Jie,XU Qiu-shi,SHI Hui-li,et al(Qingdao Public Security Bureau,Qingdao 266001,China) |
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| Abstract: | Objective To establish a MS/MS database for 90 kinds of pesticide and a rapid method for determination of 90 kind of pesticide in unknown samples.Methods Analysis conditions of Q-TOF LC/MS were optimized firstly and then 90 kinds of pesticide were analyzed by Q-TOF LC/MS-MS.By using PCDL（Personal Compound Database and Library） software,a database for 90 kinds of pesticide was established.Results 10 blood samples which contain different concentrations of pesticides（100ng/mL,500ng/mL） were analyzed and the positive rate was more than 80%.Conclusion This method is simple,sensitive and can be used for rapid screening and confirmation of pesticide. |
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| Keywords: | database LC/MS-MS Q-TOF LC/MS pesticide rapid screening and confirmation |
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