| 腐败生物检材中多种碱性滥用药物的检测 |
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| 引用本文： | 邸玉敏,朱军,常靖,崔巍.腐败生物检材中多种碱性滥用药物的检测[J].刑事技术,2010(1):3-6. |
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| 作者姓名： | 邸玉敏 朱军 常靖 崔巍 |
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| 作者单位： | 1. 中国人民公安大学,北京,100038
2. 公安部物证鉴定中心,北京,100038 |
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| 基金项目： | "十一五"国家科技支撑计划项目 |
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| 摘 要： | 目的建立腐败生物检材中多种碱性滥用药物的提取、净化和仪器分析方法。方法用环己烷作为提取溶剂液-液萃取，同时采用Bond Elut Certify小柱、甲醇淋洗、二氯甲烷：异丙醇：氨水（78：20：2）洗脱固相萃取分离提取，GC／MS、GC／NPD定性定量分析各种生物检材中的滥用药物。结果从所送死者肝组织、胃组织、心血及胃内容、尿样、各检材中均同时检出吗啡、可待因、舒乐安定和异丙嗪成份，其中肝组织含量分别为吗啡0．094μg／g、可待因0．257μg／g、异丙嗪0．110μg／g，尿液含量分别为吗啡0．334μg／ml、可待N4．054μg／ml、异丙嗪0．066μg／ml，心血含量分别为吗啡0．036μg／ml、可待N0．106μg／g、异丙嗪0．088μg／ml。结论此方法准确、可靠、科学，可以用于法医毒物分析领域体内检材多种碱性药物的检测。
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| 关 键 词： | 法医毒物分析 腐败生物检材 碱性滥用药物 |
Detection of basic abuse drugs in decay organism samples |
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| DI Yu-min,ZHU Jun,CHANG Jing,et al..Detection of basic abuse drugs in decay organism samples[J].Forensic Science and Technology,2010(1):3-6. |
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| Authors: | DI Yu-min ZHU Jun CHANG Jing |
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| Institution: | DI Yu-min,ZHU Jun,CHANG Jing,et al.(Chinese Peoples\' Public Security University,Beijing 100038,China) |
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| Abstract: | Objective To provide a extraction,purification and instrumental analysis method for the determination of basic abuse drugs in decay organism samples.Methods Abuse drugs extracted from organism samples by liquid-liquid and solid phase extraction were detected and quantified with GC/MS and GC/NPD.Using cyclohexane as the extracted solvent,and the Bond-Elut Certify cartridge columns were washed with methanol,and eluted by dichloromethane:isopropyl alcohol:ammonium hydroxide (78:20:2,v/v/v) mixed solvent.Result... |
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| Keywords: | forensic poison analysis decay organism samples basic abuse drugs |
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