| 气相色谱-负化学源质谱法检测生物样品中佐匹克隆 |
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| 引用本文： | 张蕾萍,舒翠霞,杜鸿雁.气相色谱-负化学源质谱法检测生物样品中佐匹克隆[J].刑事技术,2012(4):17-18. |
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| 作者姓名： | 张蕾萍 舒翠霞 杜鸿雁 |
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| 作者单位： | 1. 公安部物证鉴定中心,北京,100038
2. 中国医科大学,辽宁沈阳,110001 |
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| 摘 要： | 目的建立气相色谱-负化学源质谱检验生物样品中佐匹克隆的方法。方法采用OasisHLB柱进行固相萃取，NCI-GC／MS检验。结果生物样品中佐匹克隆平均萃取回收率达75．8％，最低检出限0．01μg·mL^-1，线性良好，相关系数R^2=0．9989。结论该方法操作简便快速，提取回收率高，重现性好，提取物干净，可用于实际案件。
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| 关 键 词： | 法医毒物分析 佐匹克隆 气相色谱-质谱 负化学源 |
Determination of zolpiclone in biology samples by gas chromatography-negative ion chemical ionization mass spectrometry |
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| ZHANG Lei-ping
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SHU Cui-xia
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DU Hong-yan.Determination of zolpiclone in biology samples by gas chromatography-negative ion chemical ionization mass spectrometry[J].Forensic Science and Technology,2012(4):17-18. |
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| Authors: | ZHANG Lei-ping SHU Cui-xia DU Hong-yan |
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| Institution: | (Institute of Forensic Science,Ministry of Public Security,Beijing 100038,China) |
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| Abstract: | Objective To develop a method for determination of zolpiclone in biology samples. Methods The samples were extracted by using Oasis HLB solid phase extraction column, and analyzed by gas chromatography-negative ion chemical ioni- zation mass spectrometry. Results The mean recovery rate of zolpiclone in biology samples was 75.80%, the limits of detection was 0. 01/μg·mL-1 , and the linear correlation coefficient was 0. 9989. Conclusion The method is easy to operation, reliable and can be used in the casework. |
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| Keywords: | forensic toxicological analysis zolpiclone gas chromatography-mass spectrometry negative ion chemical ioni-zation |
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