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Mitochondrial DNA control region population data from Macedonia
Authors:Bettina Zimmermann  Anita Brandsttter  Nina Duftner  Daniela Niederwieser  Mirko Spiroski  Todor Arsov  Walther Parson
Institution:aInstitute of Legal Medicine, Innsbruck Medical University, Müllerstrasse 44, A-6020 Innsbruck, Austria;bFAS Center for Systems Biology, Harvard University, Cambridge, MA, USA;cSection of Integrative Biology, University of Texas, 1 University Station, Austin, TX, USA;dInstitute of Immunobiology and Human Genetics, Faculty of Medicine, Skopje, Macedonia
Abstract:Mitochondrial DNA sequences of the entire control region were analyzed in 200 unrelated individuals from Macedonia. A total of 163 different haplotypes were found as determined by 177 polymorphic sites. The probability of a random match was calculated as 1:121 (0.83%). The basic phylogenetic structure of the Macedonian population as derived from its haplogroup distribution is in agreement with other West-Eurasian populations. Upon publication, the population data are going to be available in the EMPOP database (www.empop.org) W. Parson, A. Dür, EMPOP—a forensic mtDNA database, FSI:Genetics 1 (2) (2007) 88–92; W. Parson, A. Brandstätter, A. Alonso, N. Brandt, B. Brinkmann, A. Carracedo, et al., The EDNAP mitochondrial DNA population database (EMPOP) collaborative exercises: organisation, results and perspectives, Forensic Sci. Int. 139 (2–3) (2004) 215–226.].
Keywords:Macedonia  Population data  Entire control region  mtDNA polymorphism  Haplotypes
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