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TW2法3种标准用于中枢性性早熟患儿骨龄推断的比较
引用本文:白万晶,宁刚,曲海波,孙小妹,向承发,吴康敏,刘关键.TW2法3种标准用于中枢性性早熟患儿骨龄推断的比较[J].法医学杂志,2010,26(3):181-184.
作者姓名:白万晶  宁刚  曲海波  孙小妹  向承发  吴康敏  刘关键
作者单位:1. 四川大学,华西第二医院,四川,成都,610041
2. 四川大学,华西临床医学院,四川,成都,610041
摘    要:目的 探讨TW系列骨龄评分法中TW2(英国人标准)、TW2-CHN(中国人标准)和TW2-JP(日本人标准)3种标准对中枢性性早熟(central precocious puberty,CPP)惠儿骨龄评价的诊断价值,以及正常值临界点的确定.方法 选取确诊为CPP的病例组61例;对照组67例,其中同龄正常儿童61例,另6例为特殊对照组.两名医师独自阅每一对象左手腕部X线片,分别用3种标准测定骨龄;将骨龄与生理年龄的差值(d)用SPSS 13.0进行ROC分析.结果 (1)两名医师骨龄测定结果的K值为0.776(u=16.128,P<0.05):(2)TW2、TW2-CHN及TW2-JP 3种标准测得的ROC曲线下面积两两之间的差异无统计学意义;(3)TW2中d≥1.15岁、TW2-CHN中d≥1.25岁与TW2-JP中d≥0.65岁为敏感度、特异度都较高的点.结论 TW2、TW2-CHN及TW2-JP 3种标准时CPP患儿骨龄评价的诊断价值都较高,其中TW2-CHN对中国儿童的诊断价值最大.

关 键 词:法医学  年龄测定  骨骼  青春期  早熟  TW2法

Comparison among Three Standards of TW2 to Skeletal Age Determination in Children with Central Precocious Puberty
BAI Wan-jing,NING Gang,QU Hai-bo,SUN Xiao-mei,XIANG Cheng-fa,WU Kang-min,LIU Guan-jian.Comparison among Three Standards of TW2 to Skeletal Age Determination in Children with Central Precocious Puberty[J].Journal of Forensic Medicine,2010,26(3):181-184.
Authors:BAI Wan-jing  NING Gang  QU Hai-bo  SUN Xiao-mei  XIANG Cheng-fa  WU Kang-min  LIU Guan-jian
Institution:BAI Wan-jing1,NING Gang1,QU Hai-bo1,SUN Xiao-mei1,XIANG Cheng-fa1,WU Kang-min1,LIU Guan-jian2(1.West China Second Hospital,Sichuan University,Chengdu 610041,China,2.West China School of Clinical Medicine,China)
Abstract:Objective To discuss the diagnostic value of English,Chinese and Japanese standards of TW2 to skeletal age assessment of children with central precocious puberty(CPP),then to confirm the normal thresholds.Methods Sixty one children as patient group were definitely assured CPP.The control group had 67 children.Among them,61 were normal children,another 6 children as a special control group.Left hand-wrist X-ray radiographs were retrospectively analyzed by two doctors separately and their skeletal ages were a...
Keywords:forensic medicine  age determination by skeleton  puberty  precocious  TW2 method  
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