| 中国东部蒙古族人群15个STR基因座多态性研究 |
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| 作者姓名： | Du QX Wang J Huang YL |
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| 作者单位： | 1. 黑龙江省公安厅刑事技术处遗传室,黑龙江,哈尔滨,150008
2. 内蒙古科技大学医学院,内蒙古,包头,014010 |
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| 摘 要： | 目的调查15个STR基因座在中国东部蒙古族人群中的基因频率分布。方法应用四色荧光标记引物复合扩增技术,对105名东部蒙古族无关个的血样15个STR基因座进行多态性研究。结果在东部蒙古族人群中15个STR基因座偶合率在0.0084～0.2169之间,个体识别概率(DP)在0.7831～0.9916之间,杂合度在0.5619～0.9231之间,三联非父排除率(PE)在0.4490～0.8444之间,多态性信息总量(PIC)在0.5438～0.9178之间,15个STR基因座总TDP值为0.9999999999998,所有基因座经χ2检验符合Hard-Weinberg平衡。结论上述15个STR基因座在东部蒙古族人群中等位基因分布较好,个体识别率高,适合法医个体识别和亲子鉴定。
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| 关 键 词： | 法科学 东部蒙古族 STR基因座 复合扩增 遗传多态性 |
| 文章编号： | 1004-5619(2004)03-0164-03 |
| 修稿时间： | 2003年10月28 |
A genetic study of 15 STR loci in Chinese East Mongolian population |
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| Du QX,Wang J,Huang YL.A genetic study of 15 STR loci in Chinese East Mongolian population[J].Journal of Forensic Medicine,2004,20(3):164-166. |
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| Authors: | Du Qing-xin Wang Jian Huang Yu-li |
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| Institution: | Criminal Science & Technology Institute of Hei-longjiang Province, Harbin 150008, China. |
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| Abstract: | OBJECTIVE: To investigate the genetic polymorphisms of 15 STRs loci in Chinese East Mongolian population. METHODS: DNA samples from 105 unrelated individuals in Chinese East Mongolian population were screened by Power Plex 16 System and ABI3100 Genetic Analyzer. RESULTS: The genotype frequencies of these 15 STR loci meet the Hardy-Weinberg expectation. The Matching probability of 15 STRs loci were between 0.0084-0.2169, discriminating power (DP) at 0.7831-0.9916, heterozygosity (H) at 0.5619-0.9231, power of exclusion (PE) at 0.4490-0.8444, polymorphism information content (PIC) at 0.5438-0.9178. The total DP of 15 STRs loci is 0.9999999999998. CONCLUSION: Our results showed that the 15 STRs loci of Power Plex 16 System are valuable STR loci genetic marker system having high DP and are useful in forensic case work in Chinese East Mongolian population. |
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| Keywords: | forensic science east mongolian population STR loci multiplexing PCR genetic polymorphism |
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