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| 胶束液相色谱法在体内毒物分析中的应用 | |
| 引用本文： | 程向炜,蒋文慧,褚建新.胶束液相色谱法在体内毒物分析中的应用[J].法医学杂志,2010,26(1):56-58,63. |
| 作者姓名： | 程向炜 蒋文慧 褚建新 |
| 作者单位： | 1. 浙江警察学院,浙江,杭州,310053 2. 杭州市人民检察院,浙江,杭州,310014 3. 浙江省人民检察院,浙江,杭州,310012 |
| 基金项目： | 浙江省公安厅2008年资助项目(200801) |
| 摘 要： | 胶束液相色谱法是采用高于临界胶束浓度的表面活性剂溶液作为流动相的反相液相色谱方法。本文概述了胶束液相色谱法的基本原理和在理化分析方面的优势,介绍了其在毒品、巴比妥类镇静催眠药、苯二氮卓艹类催眠镇定药检验等方面的实际应用,认为胶束液相色谱法具有选择性高、适用范围广、生物样品处理简便等优点,可成为毒物分析的一种方法。 |
| 关 键 词： | 法医毒理学 色谱法 液相 综述[文献类型] 胶束 |
Micellar Liquid Chromatography and Its Application in Toxicological Analysis |
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| CHENG Xiang-wei,JIANG Wen-hui,CHU Jian-xin.Micellar Liquid Chromatography and Its Application in Toxicological Analysis[J].Journal of Forensic Medicine,2010,26(1):56-58,63. | |
| Authors: | CHENG Xiang-wei JIANG Wen-hui CHU Jian-xin |
| Institution: | CHENG Xiang-wei1,JIANG Wen-hui2,CHU Jian-xin3 |
| Abstract: | Micellar liquid chromatography(MLC) is a reversed phase liquid chromatography with mobile phases containing surfactant above its critical micellar concentration(CMC).The basic mechanism and ad-vantages of MLC in physicochemical analysis were reviewed,and its applications in analysis of drugs,bar-biturates,benzodiazepines were chiefly introduced in this paper.MLC is a potential method to toxicological analysis due to strong selectivity,wide application scope and easy biological samples,etc. |
| Keywords: | forensic toxicology chromatography liquid review[publication type] micellar |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |