| 家兔死后心肌酰胺A带的傅里叶变换红外光谱图像分析 |
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| 作者姓名： | Zhang HD Yang TT Zheng N Sun TY Liu L |
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| 作者单位： | 1. 中国政法大学证据科学教育部重点实验室,北京,100040
2. 华中科技大学同济医学院法医学系,湖北武汉,430030 |
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| 基金项目： | 国家自然科学基金青年科学基金项目(81001349) |
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| 摘 要： | 目的 应用傅里叶变换红外光谱成像系统研究家兔心肌酰胺A带变化与死亡时间的关系.方法 将32只家兔处死后取出心脏,20℃保存,于48h内不同时间点取样并制作切片.用傅里叶变换红外光谱成像系统绘制酰胺A带图像,分析研究死后酰胺A带阳性与阴性面积比的变化规律. 结果 48h内随死亡时间(x)的延长,酰胺A带的阳性与阴性面积比...
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| 关 键 词： | 法医病理学 谱学 傅里叶变换红外 心肌 酰胺A带 死亡时间 兔 |
Analysis of the changes of amide A in rabbit heart after death by FTIR spectroscopy |
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| Zhang HD,Yang TT,Zheng N,Sun TY,Liu L.Analysis of the changes of amide A in rabbit heart after death by FTIR spectroscopy[J].Journal of Forensic Medicine,2011,27(5):321-323. |
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| Authors: | Zhang Hai-Dong Yang Tian-Tong Zheng Na Sun Ting-Yi Liu Liang |
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| Institution: | ZHANG Hai-dong1,YANG Tian-tong1,ZHENG Na2,SUN Ting-yi2,LIU Liang1(1.Key Laboratory of Evidence Science,China University of Political Science and Law,Ministry of Education,Beijing 100040,China,2.Department of Forensic Medicine,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China) |
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| Abstract: | Objective To explore the relationship of changes of amide A in rabbit heart and the postmortem interval（PMI） by FTIR spectroscopy technique.Methods Thirty-two rabbits were sacrificed and the hearts were sampled at 20 ℃ within 48 h postmortem points.All samples were sliced and tested by FTIR spectroscopy technique.The images of amide A were created by FTIR spectroscopic imaging.The positive and negative area ratios of amide A were analyzed using imaging analysis system.Results The positive and negative area ratios declined regularly with the prolongation of death time in 48 h.There was a significant quadric relationship between the area ratios（y） of amide A（positive and negative area） and PMI（x）.The regression equation was y=0.001 x2-0.038 x＋0.747（R2=0.940）.Conclusion The ratios of positive and negative area of amide A showed a strong correlation with PMI and could be used to estimate PMI. |
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| Keywords: | forensic pathology spectroscopy Fourier transform infrared myocardium amide A postmortem interval rabbits |
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