甘肃东乡族男性24个Y-STR基因座遗传多态性(英文) |
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引用本文: | 骆继怀,孙红兵,杨鑫,哈飞,张子龙.甘肃东乡族男性24个Y-STR基因座遗传多态性(英文)[J].法医学杂志,2016(3):219-221. |
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作者姓名: | 骆继怀 孙红兵 杨鑫 哈飞 张子龙 |
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作者单位: | 1. 甘肃省证据科学技术研究与应用重点实验室,甘肃 兰州 730070;兰州市公安局刑事科学技术研究所,甘肃 兰州 730030;2. 甘肃省证据科学技术研究与应用重点实验室,甘肃 兰州,730070 |
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摘 要: | 目的检测24个Y-STR基因座单倍型的遗传多态性,探讨其法医物证学应用价值。方法应用AGCU Y24试剂盒和3130xl型遗传分析仪对154例甘肃东乡族男性无关个体的24个Y-STR基因座(DYS391、DYS389Ⅰ、DYS439、DYS389Ⅱ、DYS438、DYS643、DYS456、DYS458、DYS437、DYS635、DYS448、DYS527a/b、Y-GATA-H4、DYS447、DYS19、DYS392、DYS522、DYS393、DYS388、DYS390、DYS385a/b、DYS444)进行检测,获得其基因型分布情况。结果 154例样本中共检出153种单倍型,单倍型多样性为0.991 5和个体识别率为0.994 0。结论 24个Y-STR复合扩增体系具有较高单倍型遗传多态性和个体识别率。
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关 键 词: | 法医遗传学 多态现象 遗传 Y染色体 短串联重复序列 单倍型 甘肃 东乡族 |
Genetic Polymorphism of 24 Y-STR Loci in Dongxiang Ethnic Minority Male Resi-dents in Gansu Province of China |
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Abstract: | Objective To determine the genetic polymorphism of 24 Y-STR loci haplotype and investigate its application value in legal physical evidence.Methods AGCU Y24 kit and 3130xl Genetic Analyzer were used to detect the distribution of 24 Y-STR loci including DYS391,DYS389Ⅰ,DYS439,DYS389Ⅱ, DYS438, DYS643, DYS456, DYS458, DYS437, DYS635, DYS448, DYS527a/b, Y-GATA-H4, DYS447, DYS19,DYS392,DYS522,DYS393,DYS388,DYS390,DYS385a/b and DYS444in 154 unrelated individuals of Dongxiang ethnic minority males in Gansu province of China.Results A total number of 153 haplo-types were detected in 154 samples, the haplotype diversity was 0.9915 and the discrimination power was 0.9940.Conclusion The 24 Y-STR loci system has high haplotype diversity and discrimination power. |
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Keywords: | forensic genetics polymorphism genetic Y chromosome short tandem repeat sequences haplotype Gansu Dongxiang Population |
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