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家兔急性胰腺炎死后不同时间眼玻璃体液淀粉酶变化
作者姓名:Li XB  Zhang HY  Shao LM
作者单位:1. 温州医学院法医学教研室,浙江,温州,325027
2. 温州医学院附属二院检验科,浙江,温州,325027
3. 温州市公安局法医室,浙江,温州,325027
基金项目:温州市科委立项并资助研究项目(S2002A071)
摘    要:目的探讨急性胰腺炎死后不同时间眼玻璃体液淀粉酶变化。方法用1%牛胆酸钠诱导家兔急性胰腺炎动物模型建立,于死后不同时间和正常对照组,观察其淀粉酶变化。结果家兔急性胰腺炎死后72h眼玻璃体液淀粉酶含量(x)与死亡时间(y)存在相关关系,并导出其二项式回归方程为y=8.7420 0.7699x-0.0083x2(R2=92.62792,F=14.89734,P=0.001)。可作为推定早期损伤时间的参考指标。结论家兔急性胰腺炎死后不同时间眼玻璃体液淀粉酶改变为法医早期死亡时间推断提供了灵敏客观的实验依据。

关 键 词:死亡时间  急性胰腺炎  眼玻璃体液  淀粉酶
文章编号:1004-5619(2004)03-0143-02
修稿时间:2002年11月12

Concentration changes of amylase in vitreous humor of acute pancreatitis associated with different postmortem interval in rabbits
Li XB,Zhang HY,Shao LM.Concentration changes of amylase in vitreous humor of acute pancreatitis associated with different postmortem interval in rabbits[J].Journal of Forensic Medicine,2004,20(3):143-144.
Authors:Li Xing-biao  Zhang Hai-yan  Shao Li-ming
Institution:Department of Forensic Medicine, Wenzhou Medical College, Wenzhou 325027, China.
Abstract:Objective To investigate concentration changes of amylase in rabbits vitreous humor of acute pancreatitis associated with postmortem different interval.Methods To induce animal model of acute pan-creatitis with sodium taurocholate,observed concentration changes of amylase after different postmortem in-terval,then compared with normal.Results The concentration of amylase in vitreous humor of rabbit24h after death were related to postmortem interval significantly;The concluded formulae of the relationship between postmortem interval and amylase concentration is y=8.7420 0.7699x-0.0083x2(R2=92.62792,F=14.89734,P=0.001).Conclusion Concentration changes of amylase in vitreous humor of acute pancreatitis associated with postmortem interval may provide a new sensitive and objective method for the forensic early injury time estimation.
Keywords:postmortem interval  acute pancreatitis  vitreous humor amylase
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