| 犬组织中艾司唑仑在甲醛溶液中的稳定性 |
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| 作者姓名： | Yuan JX Wang YJ Yun KM |
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| 作者单位： | 山西医科大学法医学院; |
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| 基金项目： | 山西省自然科学基金资助项目(2007011105); “十一五”国家科技支撑计划项目(2007BAK26B05) |
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| 摘 要： | 目的 研究甲醛溶液保存的生物样品中艾司唑仑的稳定性.方法 犬以艾司唑仑37.6mg/kg剂量灌胃,2h处死,解剖取其心、肝、肾、脑并分割为1g/份,分别放置于4%甲醛溶液中固定,用高效液相色谱法测定各组织及甲醛液中的艾司唑仑含量.结果 犬心、肝、肾、脑组织随着固定在甲醛溶液中时间的延长,组织及从组织溶解到甲醛溶液中的艾...
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| 关 键 词： | 法医毒理学 艾司唑仑 甲醛 稳定性 犬 |
Stability of estazolam in dog tissues preserved in formaldehyde solution |
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| Yuan JX,Wang YJ,Yun KM.Stability of estazolam in dog tissues preserved in formaldehyde solution[J].Journal of Forensic Medicine,2011,27(2):117-9, 124. |
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| Authors: | Yuan Jiu-xi Wang Yu-jin Yun Ke-ming |
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| Institution: | YUAN Jiu-xi,WANG Yu-jin,YUN Ke-ming(School of Forensic Medicine,Shanxi Medical University,Taiyuan 030001,China) |
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| Abstract: | Objective To investigate the stability of estazolam in biological samples preserved in formaldehyde solution.Methods The dog was given intragastric administration of estazolam with a dose of 37.6 mg/kg and killed 2 h later.Heart,liver,kidney and brain of the dog were cut up into 1 g and preserved in 4% formaldehyde solution respectively.The content of estazolam in biological samples and formaldehyde solution were analyzed by HPLC at different times.Results The content of estazolam in heart,liver,kidney and ... |
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| Keywords: | forensic toxicology estazolam formaldehyde stability dogs |
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