| 断奶仔猪多系统衰竭综合征淋巴结与脾损伤的病理学观察 |
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| 引用本文： | 耿毅,汪开毓,陈德芳,黄锦炉,李成伟.断奶仔猪多系统衰竭综合征淋巴结与脾损伤的病理学观察[J].中国兽医科学,2010,40(5). |
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| 作者姓名： | 耿毅 汪开毓 陈德芳 黄锦炉 李成伟 |
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| 作者单位： | 耿毅,汪开毓,GENG Yi,WANG Kai-yu(四川农业大学,动物医学院,四川,雅安,625014;四川农业大学,动物疫病与人类健康四川省重点实验室,四川,雅安,625014);陈德芳,黄锦炉,李成伟,CHEN De-fang,HUANG Jin-lu,LI Cheng-wei(四川农业大学,动物医学院,四川,雅安,625014) |
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| 基金项目： | 教育部"长江学者和创新团队发展计划"创新团队项目 |
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| 摘 要： | 对通过临床特征与PCR确诊为断奶仔猪多系统衰竭综合征的8例自然病例进行剖检取材,常规石蜡切片与超薄切片,HE染色及醋酸铀一柠檬酸铅染色,观察了淋巴结与脾的病理学变化.肉眼观察可见淋巴结肿大,特别是腹股沟淋巴结、肠系膜淋巴结与肺门淋巴结明显肿大;脾萎缩或中度肿大.组织学观察显示,淋巴结与脾淋巴细胞坏死,数量明显减少,网状内皮细胞增生与巨噬细胞浸润,在一些网状内皮细胞与巨噬细胞的胞浆内见嗜碱性包涵体.超微结构观察显示,淋巴结与脾淋巴细胞线粒体肿胀,内质网扩张,核浓缩,边集,甚至形成凋亡小体;在巨噬细胞与网状内皮细胞核和胞浆内均可见包涵体,包涵体为大小不等,圆形、椭圆形或不规则形的均质或颗粒状2种类型,胞浆包涵体常见于肿胀的线粒体与扩张的内质网附近.表明断奶仔猪患多系统衰竭综合征可致淋巴结与脾淋巴细胞坏死、凋亡,淋巴细胞数量减少.
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| 关 键 词： | 断奶仔猪多系统衰竭综合征 猪圆环病毒2型 淋巴结 脾 病理形态学 |
Pathological observations of lymph node and spleen from pigs with postweaning multisystemic wasting syndrome |
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| GENG Yia,b,WANG Kai-yua,CHEN De-fanga,HUANG Jin-lua,LI Cheng-weia.Pathological observations of lymph node and spleen from pigs with postweaning multisystemic wasting syndrome[J].Veterinary Science in China,2010,40(5). |
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| Authors: | GENG Yia b WANG Kai-yua CHEN De-fanga HUANG Jin-lua LI Cheng-weia |
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| Institution: | GENG Yia,b,WANG Kai-yua,CHEN De-fanga,HUANG Jin-lua,LI Cheng-weia (a.College of Veterinary Medicine,b.Key Laboratory of Animal Disease , Human Health of Sichuan Province,Sichuan Agricultural University,Ya\'an 625014,China) |
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| Abstract: | Eight piglet cases with postweaning multisystemic wasting syndrome(PMWS) were confirmed by means of observation of clinical signs and PCR detection of porcine circovirus type 2.Samples of the lymph node and spleen from the 8 cases were collected,routinely made into paraffin section and ultrathin section,stained with the hematoxylin and eosin or the uranyl acetate and lead citrate,and observed by light microscope and transmission electron microscope.Enlargement occured in the lymph nodes,especially in the in... |
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| Keywords: | postweaning multisystemic wasting syndrome porcine circovirus type 2 lymph node spleen pathomorphology |
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