Diagnostic Value of PSA and AP Tests for the Detection of Spermatozoa in Postmortem Swabs from the Genital and Anal Region in Males |
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| Authors: | Laurence Weitzig M.D. Ann Sophie Schroeder M.D. Ph.D. Christa Augustin Ph.D. Tobias Raupach M.D. M.M.E. Susanne Sehner M.Sc. Sven Anders M.D. M.M.E. |
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| Affiliation: | 1. Department of Legal Medicine, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany;2. Department of Cardiology and Pneumology, University Hospital Goettingen, Goettingen, Germany;3. Department of Medical Biometry and Epidemiology, University Medical Center Hamburg‐Eppendorf, Hamburg, Germany |
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| Abstract: | The aim of this study was to clarify whether positive results for prostate‐specific antigen (PSA) and acid phosphatase (AP) occur in postmortem swabs from the genito‐anal region in males (n = 80; 4 regions) and females (n = 20; 3 regions) and to calculate the positive predictive value (PPV) concerning the presence of spermatozoa. In male subjects, the highest incidence of positive test results was found in urethral swabs (PSA 76%, AP 71%) and the lowest frequencies appeared in perianal and rectal swabs (15–20%). Microscopic evaluation for spermatozoa was positive between 39% in urethral swabs and 1% in rectal swabs. PPV regarding positive identification of spermatozoa was 33.3% for PSA and 31.5% for AP. The combination of both tests yielded a PPV of 38.2%. In female cases, no spermatozoa were identified, and one case was PSA‐ and AP‐positive in perianal swabs. Our findings indicate that PSA and AP tests are of limited value for the postmortem detection of spermatozoa in male subjects. |
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| Keywords: | forensic science prostate‐specific antigen acid phosphatase forensic casework semen spermatozoa |
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