双性同体的重新认识：批评·理论·方法

目前对英国小说家弗吉尼亚·伍尔夫的双性同体理论的争议大多局限于科学归纳的方法,忽视了其中的交往与对话性。若以哈贝马斯的交往行为理论为参照系,则可以看出双性同体所体现的是一种交往行为,它作为一种具有不确定性及对话性等特点的"活"的主体,与其内部及其他主体之间存在着动态的交往关系。对于当前思维范式与批评方法来说,运用交往行为理论来研究双性同体,可以推动传统的批评模式走向重视各种话语交往的语境批评。     

美国专利蟑螂的新近立法评析及其启示

专利蟑螂已经成为美国专利制度中一个十分严峻的问题,美国政府不断出台专利法修订草案和政策,意图遏制专利蟑螂,并取得了不错的成效。然而,从近期美国参众两院提交的诸项法案来看,尽管存在分歧,但其整体立场已经发生明显转变,倾向于优待专利蟑螂。由此,以设立双方复审程序、提高禁令颁发标准以及限制司法管辖为代表的诸多重要专利司法改革成果,都将可能遭到弱化。结合美国的经验教训,我国应当尽早认识专利蟑螂并着手应对,从考察开放许可专利实施情况、增加"权利人商业模式"作为判赔考量因素、细化司法管辖规则、完善专利无效制度以及构建全面打击专利假冒行为制度等多个维度,预防和遏制专利蟑螂。     

Paraquat myopathy: report on two suicide cases.

We describe two suicide cases in which old paraquat was ingested. In conjunction with lung involvement a pronounced degeneration was observed in skeletal muscle of one who died on the 14th day after the ingestion. The following sarcoplasmic or endoplasmic reticulum Ca2+ ATPase (SERCA) monoclonal antibodies were used for skeletal muscle fiber typing by an immunohistochemical method: NCL-SERCA1, reactive with type 2 fiber (fast-twitch), and NCL-SERCA2, reactive with type 1 fiber (slow-twitch). The examination revealed that the remarkably degenerated fibers belonged to type 1 muscle fibers. This case showed an abrupt increase of plasma CK levels (1796 mU/ml) on the fifth day after the ingestion. The authors presume that the damage to the skeletal muscle had occurred in this period. The degeneration of the muscle seemed to be attributable to the long retention of paraquat in the tissue because these findings were not observed in the other case who died on the fifth day. Paraquat-induced myopathy may develop in prolonged paraquat poisoning. The examination of CK levels in plasma will be useful for diagnosis of damage of skeletal muscle.     

Exporting Gender Injustice: The Impact of the U.S. War on Drugs on Ecuadorian Women

Numerous researchers have documented the gendered impact of the United States’ domestic war against drugs. Women incarcerated for non-violent drug offenses are the fastest growing segment of America’s prison population because of the harsh penalties for using, selling and transporting illegal substances. The impact of U.S. drug policy on women in other countries, in contrast, has been overlooked. This paper argues that the greatly increased imprisonment of women in Ecuador for drug-related offenses is collateral damage of the U.S. war on drugs. The impact of the expansion of women’s imprisonment in Ecuador appears to be particularly damaging to the inmate’s children who frequently join their mother in prison. U.S. policy should not be exported to other countries before having a clear picture of the unintended negative consequences.     

The forensic taxonomic debate on Cannabis: semantic hokum.

It has been asserted that there are legal species of marihuana plants, and this contention has generated frequent court challenges of criminal prosecutions involving marihuana. Invariably the claim is made that the name C. sativa used in legislation is insufficiently comprehensive to proscribe all forms of marihuana. The maneuver being used, alarmingly, is potentially applicable to innumerable other materials, but its success is based on a failure to appreciate the subjective nature of taxonomy and the little-known but critical ambiguities which are inherent in scientific names. The complex principles and operational conventions of biological nomenclature are presented in elementary fashion. Despite important technical constraints on the use of scientific names, some facts are clear: these names are used subjectively, they may be highly ambiguous, the consensus on use of these names is liable to change with time and, most important, quite permissibly they may have substantially different meanings to different users. The claim that there are legal species of Cannabis merely amounts to a semantic ploy in which certain of the variants of Cannabis that have customarily been understood to be denoted by the species name C. sativa, and which are clearly understood to be proscribed, are simply arbitrarily redefined as different species. This ploy has proven unsuccessful in all cases where scientific evidence was adequately presented by the state and in all important court cases where the issue was critically examined.     

Toxicological screen on gastric aspirates: the Singapore experience.

In the early eighties, in response to increasing self-poisoning incidents by pharmaceuticals in Singapore, a comprehensive wide-sweep screen for these drugs in clinical gastric aspirates was devised and implemented by us. The toxicological screen which involved quadruplicate extractions, two in acidic conditions and the other two in alkaline conditions, required the following analyses to be carried out: UV on the acidic fraction, TLC on the basic fraction and mega-bore capillary GC/NPD (nitrogen phosphorus detector) on the combined fraction. The combined fraction if necessary was subjected to GC/MS analysis. Our screen satisfied the need to confirm the analytical outcome of one method by another. Combining the acidic and basic fractions for a single GC analysis saves on instrument time and manpower. All coma and emergency cases were required to undergo GC/MS analysis to prove the identity of toxic agents beyond reasonable doubt. Quality control procedures were instituted at key steps to ensure quality of analytical outcome.     

Commitment and Consequences: Reneging on Cosponsorship Pledges in the U.S. House

We argue that bill cosponsorship in Congress represents an institutional arrangement that provides credibility to commitments of support. We predict that if cosponsorship fosters legislative deals, MCs will only rarely back out on their pledges to support a bill if it comes up for a floor vote, and when they do, these choices will reflect strategic calculations. Further, legislators who violate their cosponsorship agreements will face punishment from colleagues, compromising their ability to gain support for their own bills. We explore the causes and effects of MCs' choices to renege on a pledge by voting no on a bill for which they were a cosponsor, focusing on all cosponsorship decisions in the 101st–108th Houses. The results reveal that patterns of reneging and its consequences are consistent with the idea that cosponsorship functions as a commitment mechanism.     

U.S. policy on health inequities: the interplay of politics and research

What is the relationship between scientific research and government action in addressing health inequalities in the United States? What factors increase the impact of scientific research on public policy? To answer these questions, we focus on racial and ethnic disparities in health status and health care in the United States. We first review the history of the disparities issue to elucidate how the continual and persistent interplay between political action and scientific research drives government policy. We then analyze two recent government-sponsored reports about racial and ethnic disparities to understand the strategic consequences of issue framing. We draw lessons about how disparities research can have a greater impact on public policy.