The inhibiting factors that principal investigators experience in leading publicly funded research

Securing public funding to conduct research and leading it by being a principal investigator (PI) is seen as significant career development step. Such a role brings professional prestige but also new responsibilities beyond research leadership to research management. If public funding brings financial and infrastructure support, little is understood about the inhibiting factors that publicly funded PIs face given the research autonomy offered by publicly funded research. Our study finds that there are three key PI inhibiting factors (1) political and environmental, (2) institutional and (3) project based. Traditional knowledge, skills and technical know-how of publicly funded PIs are insufficient to deal with the increasing managerial demands and expectations i.e. growing external bureaucracy of public funding agencies. Public funding is no longer the ‘freest form of support’ as suggested by Chubin and Hackett (Peerless science: peer review and US science policy. Suny Press, New York, 1990) and the inhibiting factors experienced by publicly funded PIs limits their research autonomy. We also argue that PIs have little influence in overcoming these inhibiting factors despite their central role in conducting publicly funded research.     

Social preferences for the inclusion of indirect benefits in the evaluation of publicly funded health services: results from an Australian survey

The inclusion of both monetary and non-monetary indirect benefits in economic evaluations of public health programmes and services can have significant distributive effects between patient groups. As a result, some patients may be advantaged and others disadvantaged for reasons not directly related to health outcomes or (direct) treatment costs. In pluralistic democracies, there is a case for consulting the community on the fairness of policies that have such distributive implications. This paper reports the results of two pilot studies aimed at uncovering the preferences of the Australian public for the inclusion of indirect benefits in the evaluation of services for its national health scheme, Medicare. The initial survey found some support for taking account of non-monetary indirect benefits - for example, the social contribution made by parents of young children and carers of elderly relatives. By contrast, there was little support for giving high taxpayers priority access to general Medicare services, to life-saving organ transplants, or to very costly drugs, despite the indirect social benefits of doing so. However, such support increased significantly in the follow-up study when the outcomes were characterised as certain, identifiable and health related, and the opportunity costs of failing to take account of indirect benefits were made very clear. The follow-up survey provided evidence of public scepticism about the willingness or ability of government to use additional tax receipts for socially beneficial purposes, and/or a preference for programmes and services that focus on health rather than welfare more generally.     

Questioning the psycho-socio-cultural factors that contribute to the cases of suicide attempts: an investigation

Suicide attempts can be described to include all actions taken by an individual to end their life as a result of acute desperation. In parallel with the changes in the make-up of human societies both globally and in this country in recent years, suicide attempts are receiving attention in ever increasing proportions. The current study is aimed at investigating the psycho-socio-cultural factors that contribute to the known cases of suicide attempts. The study included 116 cases admitted to the Emergency Internal Medicine and Surgery Units of the University of Istanbul, Faculty of Medicine Hospital between 1 December 1998 and 31 May 1999. In only 47 cases, a 30-point questionnaire was used in several face-to-face interviews with the patients following the preparation of a clinical case study. In establishing the socio-demographic, socio-cultural and socio-economic attributes of each individual case, a range of contributing effective factors is questioned. Including the specific reasons for each suicide attempt, the emotional state of the individual prior to the suicide attempt, the type of suicide action chosen and reasons for this selection, immediate family structure, personal psychiatric antecedent, substance abuse. The results of our investigations are compared with the existing literature in a multi-faceted discussion.     

PCR扩增3因素对低拷贝模板STR分型的影响研究

目的探讨低拷贝模板(low copy number,LCN)STR扩增方法,提高LCN检材的检验成功率。方法采用Profiler P lusTM试剂盒与9947A对照DNA,改变Taq酶量、体系、循环次数3个因素进行扩增检验,了解各变量对扩增检测的影响。结果对低拷贝模板DNA,单纯增加Taq酶量或反应体系,扩增效率改善不明显;增加循环数,显著提高检验灵敏度;低于0.01ng的模板DNA,同时增加扩增体系、Taq酶量、循环数在一定程度上提高扩增效率。结论对于影响扩增的Taq酶量、体系、循环次数3个因素中,循环数影响最大,但应慎用34次及以上循环数;三者同时增加,对于低于0.01ng模板DNA的扩增可有效改善。     

Conflict of interest in clinical research: direct payment to the investigators for finding human subjects and health information

The recent death of teenager Jesse Gelsinger in a drug therapy trial has drawn attention to how financial conflicts of interest may compromise patient protection. While research institutions throughout the world have instituted a variety of conflict of interest guidelines, the potential conflicts associated with investigators receiving direct payment from private companies for both the recruitment of patients and the running of clinical trials in pharmaceutical research remains a relatively unexplored area. Clinical researchers undoubtedly deserve to be reasonably compensated for their participation. But these incentive mechanisms also have the potential to create conflicts of interest--both real and perceived.     

To act or not to act, that is the question: informed consent in a criminal perspective

Some years ago the doctor was seen as the one who "knows better", and it was absolutely unconceivable that the patient could refuse the suggested treatment or even ask any questions about it. Differently, nowadays doctors face demands to keep their patients informed and can even be sued when they act without patient knowledge and consent. On the patient's side this new paradigm does not necessarily legitimate euthanasia--still criminally forbidden in most parts of the world--but allows some kind of personal power over body, health and life, materialized in advance directives. On the doctor's side, it entails a change in the list of good medical practices, imposing the doctrine of informed consent and the prohibition of dysthanasia.     

盗用、滥用他人真实签章的票据行为的责任归属分析

盗用、滥用他人真实签章而为票据行为应该如何定性和分配责任归属,理论上和各国实务中都存在争议。笔者通过分析此种行为的特殊性,比较依据票据无权代行和票据伪造两种方式分别处理此种行为结果的不同,在介绍外国相关处理方法的基础上,得出结论,为我国票据立法处理此类难题提出思路和构想。     

Social perception of rape: how rape myth acceptance modulates the influence of situational factors

This study assessed the role of rape myth acceptance (RMA) and situational factors in the perception of three different rape scenarios (date rape, marital rape, and stranger rape). One hundred and eighty-two psychology undergraduates were asked to emit four judgements about each rape situation: victim responsibility, perpetrator responsibility, intensity of trauma, and likelihood to report the crime to the police. It was hypothesized that neither RMA nor situational factors alone can explain how rape is perceived; it is the interaction between these two factors that best account for social reactions to sexual aggression. The results generally supported the authors' hypothesis: Victim blame, estimation of trauma, and the likelihood of reporting the crime to the police were best explained by the interaction between observer characteristics, such as RMA, and situational clues. That is, the less stereotypic the rape situation was, the greater was the influence of attitudes toward rape on attributions.     

Defending the scientific foundations of the firearms and tool mark identification discipline: responding to recent challenges

Recent challenges have brought the discipline of firearms and tool mark identification to the forefront in recent court cases. This article reviews those challenges and offers substantial support for the scientific foundations of the firearms and tool mark identification discipline. A careful review of the available literature has revealed that firearms and tool mark identification is rooted in firm scientific foundations, critically studied according to the precepts of the scientific method culminating in the Association of Firearms and Toolmark Examiners' Theory of Identification. Firearms and tool mark identification has been validated in a manner appropriate for evidence of the kind to be expected in firearms and tool mark examinations. Proficiency tests and error rates have been studied and can provide consumers of the disciple with a useful guide as to the frequency with which misidentifications are reported in the community using appropriate methodologies and controls. As a result, the primary issues in recent challenges do not invalidate the firearms and tool mark discipline as a science nor should it detract it from its admissibility in a court of law.     

The influence of right or left handedness on the ability to simulate handwritten signatures and some elements of signatures: A study of Arabic writers

It has been widely assumed since the 1970s that right-handed writers, on average, do not write or simulate handwriting any better than left-handed writers. This study has dug deeper into that question, to find narrow language environments which left-handed and right-handed writers simulate with different degrees of success or making different types of errors. These might provide useful markers of handedness in writers or forgers. The sample of 823 native Arabic-writing adults, 763 right handed and 60 left handed, first attempted to simulate two Arabic signatures. As expected, the accuracy of the simulations of the two groups was not significantly different. Simulation accuracy of a variety of narrower elements was then measured to search for small environments in which the two groups performed differently. Two elements – slant and alignment – were significantly more poorly simulated by left-handed subjects than right-handed subjects, although the differences were not great enough to be useful in suggesting the handedness of a forger. These differences in simulation accuracy were not totally explored or explained. Instead, the differences in types of errors to slant and to alignment were investigated. Left-handed simulators, but not right-handed simulators, showed a strong tendency that had been predicted for both groups: to slant strokes and letters toward the side of the writing hand, when the target strokes and letters slanted in the opposite direction. The difference between the handedness groups was great enough that a strong preference for leftward slant in an Arabic writer or forger might suggest left handedness, but not, of course, rule out right handedness. Right-handed simulators, but not left-handed simulators, showed a strong tendency that had also been predicted for both groups: for the line of writing to be higher on the side where the writing hand was located. Again, the difference between handedness groups was great enough that a strong tendency for the writing line to fall to the left in Arabic writing and simulation might suggest right handedness, but would certainly not rule out left handedness. Thus, suggestive, but not absolute, markers of handedness have been found. In an effort to explain these almost mirror-image patterns, it was noticed that the operation of two more tendencies, in addition to the operation in both groups of the two predicted tendencies, might explain the patterns of the data. If we assume that both handedness groups tended to slant toward the writing hand and tended to make the writing line higher on the side of the writing hand, the two other tendencies operating in both groups would have been a tendency to slant strokes and letters toward the end of the writing line, and a tendency for writing to fall toward the end of the writing line. The operation of these four tendencies would account quite well for the right-handed and left-handed patterns in the two groups.     

威慑与矫正--论法律对医疗事故的预防作用

医疗事故应当“以防为主”。法律对医疗事故的预防作用主要有两条思路：一是传统的过错责任体系，强调对于个别医生的威慑，促使其提高注意力标准从而避免医疗事故；二是正在研究的“无过错补偿制度”，其关注的是整个医疗行业，试图矫正现行的医疗体制．利用制度的记忆来避免医疗事故的发生。由于无过错责任真正从根源上探寻医疗事故的原因，所以它将是有效的预防措施。但是要实现无过错机制的预防功能，必须建构起相应的配套制度，从而从根本上降低医疗事故的发生率。     

Understanding the factors that affect the severity of juvenile stranger sex offenses: the effect of victim characteristics and number of suspects

Understanding factors that affect the severity of a juvenile-stranger sexual assault has implications for crime prevention, and potentially, the assessment and treatment of juvenile sex offenders. This study investigated how victim characteristics and the number of suspects affected the use of physical violence and weapons and the occurrence of penetration in 495 allegations of sexual assault committed by juveniles against strangers. Statistically significant interactions between victim age and gender were found for occurrence of penetration and use of violence. Differences in offense characteristics were also found between offenses with varying victim-suspect age differences. When comparing the rate of penetration in the presence and absence of violence, little change was observed for lone suspects. However, the rate of penetration increased significantly for groups in the presence of physical violence, suggesting that violence in this context may be more expressive than instrumental. Theoretical explanations and practical implications are considered.     

The Police Officer Perception Project (POPP): An experimental evaluation of factors that impact perceptions of the police

Objectives

To experimentally evaluate the effects of attire and patrol strategy esthetics on participants’ perceptions of police officers.

Methods

Using a rigorously controlled experimental methodology, I present participants (N = 307) with images of police officers in different attire (i.e., uniform and civilian) and patrol strategies (i.e., on a bicycle, on foot, and in a vehicle) and measure their perceptions of these officers as aggressive, approachable, friendly, respectful, and accountable.

Results

Participants express relatively positive perceptions of the police; however, their perceptions vary as a function of sociodemographics, attire, and patrol strategy. Police officers are generally perceived more favorably when presented in police uniform than when presented in civilian clothing. Police officers are also generally perceived more favorably when presented on a bicycle and/or on foot than when presented in a vehicle.

Conclusions

Merely observing police officers in different attire and patrol capacities produces substantial variation in perceptions of those officers. Given that most ‘police interaction’ occurs in relatively unceremonious settings without any exchange of formal dialogue between the public and the police (e.g., observing a police officer in passing), these findings are particularly fruitful for informing both research and practice. This is the first known study to use an experimental methodology to examine how esthetic factors of different patrol strategies can impact perceptions of the police.

     

中国法律史研究的可能前景:超越西方,回归本土?

近代以降,西方的法律概念和法学理论随着坚船利炮不断“侵入”中国,并逐步支配了中国的法制建设和法律教育。在西方法学宰制下,固有的中国法律史研究范式也被取而代之,从而深刻地影响了我们对中国法律史的理解和叙述。为了克服西方法学宰制下的中国法律史研究的弊端,真正理解和深刻领悟中国法律史的独特性和真精神,很有必要采取“超越西方,回归本土”的态度。在这种情形下,我们既要用“内在视角”来认识中国法律史的固有内涵,又要用“外在视角”来照亮中国法律史的独特意蕴。