The determination of ethylene glycol in biological objects in the presence of propylene glycol]

Therapeutic application of drugs containing propylene glycol 1.2 as a solvent may distort the results of forensic chemical detection of ethylene glycol from its oxidation products. Practical examples illustrate the possibility of ethylene glycol determination by gas chromatography in the presence of propylene glycol.     

The forensic chemical determination of remantadine in biological material]

Suggests new microcrystalloscopic tests for the identification of remantadine and assesses the specificity and sensitivity of these tests. Describes a thin-layer chromatographic technique for remantadine identification.     

生物样品中苯二氮卓类药物检验概述

概述了苯二氮卓类药物的种类、性质和生物样品中苯二氮卓类药物的提取净化及检验方法。提取净化方法包括液-液萃取法、固相萃取(SPE)、固相微萃取(SPME)。检验方法有免疫测定法、TLC、GC、HPLC、GC/MS等。     

The detection of amizil in studying different objects]

Amisyl possesses toxic effect and it may become an object of forensic chemical laboratory analysis. Reactions of staining with reagents Marki, Frede and sulphuric acid as well as with reagent Dragendorf-orange residue--were used for amisyl identification. Method of amisyl detection in sorbent thin layer and identification by maximum light absorption in 258 nm area was also suggested. Usefulness of methods developed for amisyl analysis during investigation of pharmacological substances and human urine was studied.     

Fatal doses and concentrations of drugs in biological objects

Information on the lethal doses and concentrations of drugs in biological objects is essential for the diagnosis of drug poisoning. Methods for measuring the concentrations of some drugs in the blood and urine have been developed and tables of lethal doses, concentrations, and metabolism coefficients for drugs most often occurring in forensic medical practice are offered. A method for estimating the drug dose which led to a lethal outcome is suggested.     

生物样品中鸦片类毒品检验概述

概述了近 5年来生物样品中鸦片类毒品的检验情况 ,其中包括鸦片类毒品的主要种类及结构 ,鸦片类毒品在体内的代谢 ,LLE、SPE和SFE等提取净化技术 ,免疫测定、GC/MS、HPLC和LC/MS等检测方法。     

The detection of aromatic substances in biological material]

The author presents experimental data and suggests a method for extraction of aromatic substances from the blood, urine, lavage water, stomach and its contents, liver and kidneys. The extract is dissolved in 96% ethanol and the aromatic substances are detected in reactions with hydrochloric acid, Marki's reagent, 2,4-dinitrophenylhydrazine, diazotized o-dianisidine, phthivazide, chromotropic acid by UV spectrophotometry, thin-layer and gas-liquid chromatography. The sensitivity of the method is 0.1-0.5 mg %.