Hydrocephalus: a fatal late consequence of mumps encephalitis

Common and usually self-limited diseases may occasionally have fatal consequences. Hydrocephalus is a very rare complication of mumps, with just a few cases reported in the literature. Here we report a fatal case of hydrocephalus presenting 19 years after mumps encephalitis. The long latency period between encephalitis and hydrocephalus-associated symptoms makes this case particularly interesting.     

A biomechanical analysis of the causes of traumatic brain injury in infants and children

There is significant disagreement among medical professionals regarding the mechanisms for infant brain injury. This disagreement is due in part to the failure by some to acknowledge and incorporate known biomechanical data and models into hypotheses regarding causes. A proper biomechanical understanding of the mechanisms of traumatic brain injury (TBI) challenges many published and testified assumptions regarding TBI in infants and children. This paper analyzes the biomechanical relationship between the causes of TBI in infants and children, and their physiological consequences. Loading characteristics, injury parameters and criteria, scaling, failure characteristics, differences between infants and adults, and impact due to falls are described and discussed in the context of the laws of mechanics. Recent studies are critiqued with reference to their contribution to an understanding of brain injury mechanisms. Finally, methods for improving our currently incomplete knowledge of infant head injuries, and their mechanisms, consequences and tolerances are proposed. There is an urgent need for close collaboration between physicians and biomechanicians to objectively and scientifically evaluate infant head injuries to further define their mechanical bases, and to assist in their diagnosis and treatment.     

Bureaucratic corruption as a consequence of the Gulf migration: The case of North Yemen

Sizable migration of workers from North Yemen to other Gulf nations, beginning in the 1960s and continuing through the 1980s, produced a large influx of funds into the nation in the form of workers' remittances. This produced a general rise in living standards and improved balance-of-payment statistics, but also greatly increased corruption as poorly-paid officials struggled to make a living in the inflated economy and private parties sought to circumvent economic regulations. Reform efforts met with apathy or even violence, and corruption eventually reached systematic if not systemic levels. Many Yemeni migrants have recently been repatriated in the wake of the Gulf War. Whether or not this will reduce corruption depends upon many factors, such as the activities of the nation's increasingly independent press and the successful exploitation of oil and gas reserves.     

Presbyterian Hospital of Dallas v. Harris: a dubious consequence of piecemeal health care legislation

For almost forty years, legislators have advocated comprehensive measures designed to assure Americans quality health care. Instead of implementing an integrated health care plan, Congress has intermittently enacted statutes which address specific health care delivery problems. At times the judiciary has stretched the ambit of existing health legislation in response to particular plaintiffs' urgent claims. This Case Comment examines the dilemma of piecemeal legislation and judicial policymaking as exemplified by Presbyterian Hospital of Dallas v. Harris, a Fifth Circuit Court of Appeals health care financing decision whose outcome Congress has flatly rejected.     

Parting the ivory curtain: understanding how universities support a diverse set of startups

Universities are widely recognized as a critical source of technological innovation and are heralded for the entrepreneurial ventures cultivated within their walls. To date, most research has focused on academic entrepreneurship—new ventures that spin out of academic laboratories. However, universities also give rise to startups that do not directly exploit knowledge generated within academic laboratories. Such firms—and the societal and economic benefits they create—are an important contribution of modern universities. We propose a framework for understanding the full scope of university entrepreneurship and its driving factors, with the goal of providing scholars, university administrators, and policymakers with insights regarding the resources required to foster entrepreneurship from within the ivory tower.     

Pragmatic implication in the interrogation room: a comparison of juveniles and adults

Journal of Experimental Criminology - Pragmatic implication is the phenomenon that individuals process information “between the lines” and hear things that are implied but not asserted....     

Own-age bias in video lineups: a comparison between children and adults

Abstract

The present study investigated whether child (six–eight years of age) and adult witnesses (18–29 years of age) would exhibit an own-age bias when trying to identify targets from video lineups. One hundred and eighty-six participants viewed two filmed events that were identical, except one starred a child target and one a young adult. After a delay of two–three days each witness saw a lineup for the child and adult target. Children exhibited an own-age bias and were better at correctly identifying the own-age target from a target-present (TP) lineup and made more correct rejections for the own-age target-absent (TA) lineup. Adults however, showed a reversed own-age bias for the TP lineups as they made more correct identifications for the child target, but exhibited no bias for the TA lineups. The results suggest that differences in identification accuracy may be due to whether witness age and suspect age overlap.     

Putting community risk in perspective: a look at correlations, causes and controls

Much research, but not all, appears to show that persons with severe mental illness are more dangerous and violent than others; but it is misleading and feeds the stigma cannon. This paper critically reviews reported correlations between severe mental illness and violence, examines their statistical confounds, highlights studies which seek causal mechanisms explaining the associations, points to what those causal mechanisms tell us about controlling risk in the community, and reviews legal attempts to control community risk in light of those causal mechanisms.     

Comparative characteristics of chest cavity injuries in children and adults as a result of a blow from a solid blunt object

Deformity character and mechanism of thoracic injury occurrence in children regarding different variants of striking effect of solid blunt objects were studied. It was found that the bone frame of a middle part of rear and lateral surfaces of thorax is most often damaged and isolated incomplete fractures of 2 to 9 ribs occur (in adults - multiple, complete fractures). In case of wide striking surface 3 to 10 ribs are injured both in children and in adults, and construction flexion fractures are noted while in case of blows with limited surface local extension fractures with injuries of up to 3 adjacent ribs are seen.     

Trials and tribulations of using beta-amyloid precursor protein immunohistochemistry to evaluate traumatic brain injury in adults

Axonal pathology is increasingly identified by beta-amyloid precursor protein (betaAPP) immunohistochemistry in the brains of patients who may or may not have a history of trauma. The presence of betaAPP-IR(+) has been variously interpreted as either that diffuse traumatic axonal injury (TAI) is indeed a universal finding in cases of fatal traumatic brain injury (TBI) or there are other causes of betaAPP-IR(+) axons which under certain circumstances may be sufficient to mimic TBI and therefore make the medico-legal interpretation of certain cases very difficult. To address some of the uncertainties we have undertaken a detailed analysis of the amount and distribution of betaAPP immunohistochemistry in 63 cases of fatal TBI, 17 cases of patients dying after cardiac arrest, 12 cases dying in association with status epilepticus, 3 cases of carbon monoxide (CO) poisoning, 13 cases of hypoglycaemia and in 60 controls. Three patterns of betaAPP-IR(+) were identified. First, diffuse multi-focal, second, corresponding to the outline of an infarct or haematoma, and thirdly a mixture of the two. The first pattern was seen in cases of the lesser grades of TAI, CO poisoning, and hypoglycaemia, the second pattern in cases in which there was evidence of raised intracranial pressure and the third in cases of severe TAI. It is concluded that the proper interpretation of cases requires the examination of a sufficient number of blocks ( [Formula: see text] ), processing using standardised protocols including betaAPP immunohistochemistry and in some cases the mapping of any IR(+) on anatomical line diagrams. betaAPP carried out on a small number of randomly taken blocks is likely to lead to misinterpretation of the clinico-pathological correlations and possibly to a miscarriage of justice.     

Drawing conclusions about causes from systematic reviews of risk factors: The Cambridge Quality Checklists

Systematic reviews summarize evidence about the effects of social interventions on crime, health, education, and social welfare. Social scientists should also use systematic reviews to study risk factors, which are naturally occurring predictors of these outcomes. To do this, the quality of risk factor research needs to be evaluated. This paper presents three new methodological quality checklists to identify high-quality risk factor research. They are designed so that reviewers can separately summarize the best evidence about correlates, risk factors, and causal risk factors. Studies need appropriate samples and measures to draw valid conclusions about correlates. Studies need prospective longitudinal data to draw valid conclusions about risk factors. And, in the absence of experimental evidence, controlled studies need to compare changes in risk factors over time with changes in outcomes to draw valid conclusions about causal risk factors.

Hate crimes and stigma-related experiences among sexual minority adults in the United States: prevalence estimates from a national probability sample

Using survey responses collected via the Internet from a U.S. national probability sample of gay, lesbian, and bisexual adults (N = 662), this article reports prevalence estimates of criminal victimization and related experiences based on the target's sexual orientation. Approximately 20% of respondents reported having experienced a person or property crime based on their sexual orientation; about half had experienced verbal harassment, and more than 1 in 10 reported having experienced employment or housing discrimination. Gay men were significantly more likely than lesbians or bisexuals to experience violence and property crimes. Employment and housing discrimination were significantly more likely among gay men and lesbians than among bisexual men and women. Implications for future research and policy are discussed.     

Challenging the validity of a transfer of an opposition: reformatio in peius ex officio examination of transfer by EPO Board

On a request for a transfer of an opposition during the courseof opposition proceedings, the Opposition Division decided toaccept such a transfer and to maintain the patent in amendedform. The opponent appealed and the proprietor challenged thevalidity of the transfer of the opposition in its reply. Didthe principle of reformatio in peius apply? Should the Boardcarry out an ex officio examination of the validity of the transfer?     

Advantage of affinity histochemistry combined with histology to investigate death causes: indications from sample cases

Mast cell histochemistry has been proposed in addition to classic histological methods to estimate the course of traumatic events before and after death. We have addressed the utility of this approach on nine victims of different types of trauma. Sections of wounded skin were stained with hematoxylin and eosin and with fluorescent avidin to tag mast cells. Mast cell numbers were evaluated by both direct and digitalized counts. Intact skin was used as control. The results on mast cells implemented the findings upon hematoxylin and eosin stain and helped to put the wounds and death in chronological sequence. Digitalized morphometry allowed to reduce intra- and inter-observer variation. We conclude that combined histological and histochemical analyses can be of practical use in forensic pathology, that a preliminary setting of the reference values is needed for each laboratory, and that image analysis can be of help for the quantification of the results.