Allele frequencies of the ACTBP2 (=SE33), D18S51, D8S1132, D12S391, D2S1360, D3S1744, D5S2500, D7S1517, D10S2325 and D21S2055 loci in a German population sample

A population study on 10 tetrameric STR loci (ACTBP2 (=SE33), D18S51, D8S1132, D12S391, D2S1360, D3S1744, D5S2500, D7S1517, D10S2325, D21S2055) was performed with Germans from Bavaria.     

Allele frequencies of six miniSTR loci (D10S1248, D14S1434, D22S1045, D4S2364, D2S441 and D1S1677) in a Spanish population

Allele frequencies and forensic parameters for six miniSTR autosomal loci (D10S1248, D14S1434, D22S1045, D4S2364, D2S441 and D1S1677) were obtained from a sample of 264 unrelated individuals from Spain. No significant deviations from Hardy-Weinberg expectations were found. Due to the small PCR products (<125 bp), the use of these non-CODIS (NC) miniSTRs can increase the probability that a degraded sample can be typed. Additionally, these systems can be used in routine paternity analyses where more markers are needed to increase the power of exclusion or in complex paternity cases (e.g. involving closely related individuals).     

Allele frequencies of six STR loci (D3S4536, D4S2633, D5S2500, D9S925, D9S1118 and D20S481) in Chinese Han population

POPULATION: Over 265 unrelated individuals from Han population living in Wuhan, China.     

Thai population data on 15 tetrameric STR loci-D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA

The genetic variations for 15 short tandem repeat (STR) loci-D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA, were performed on a population of 210 unrelated Thai individuals using the commercially available AmpF/STR Identifiler kit.     

Allele frequencies for nine STR loci (D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820) in the Italian population

Genotype and allele frequencies for STR loci D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820 were investigated in 289 unrelated Italian Caucasian individuals from the North and South regions. After co-amplification by polymerase chain reaction, automatic DNA profiling of these nine STR loci was performed by ABI PRISM((R)) 310 DNA Genetic Analyzer. For each locus, statistical parameters for forensic and paternity purposes were then calculated; the combined power of discrimination and the combined power of exclusion of all nine loci were 0.9999999999917 and 0.99992 for the Northern population and 0.9999999999921 and 0.99991 for the Southern population.     

Population genetics of the STRs D3S1358, FGA, D2S1338, D8S1179, D21S11, D18S51 and D19S433 in the Pomerania-Kujawy region of Poland

Allele frequencies for seven STRs were obtained from a sample of 789 unrelated individuals born in the Pomerania-Kujawy region of Poland.     

Database of nine tetrameric STR loci--D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820 in Thai population

Allele distributions for the nine STR loci included in the AmpFlSTR Profiler Plus kit were evaluated in a Thai population of 300 unrelated individuals.     

Population genetic studies on the tetrameric short tandem repeat loci D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820 in Egypt.

The short tandem repeat loci (STRs) D3S1358, VWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820 and a locus allowing for sex-discrimination (amelogenin) can be co-amplified by the polymerase chain reaction using a commercially available kit (AmpFlSTR Profiler plus, Perkin-Elmer Biosystems, San Jose, CA) and subsequently typed using capillary electrophoresis (ABI Prism 310 Genetic analyzer, Perkin Elmer Applied Biosystems, San Jose CA). To establish databases for these loci for an Arab population sample from Egypt, 140 unrelated persons were typed. Analysis of these data revealed that all loci except for VWA were in Hardy-Weinberg equilibrium, that the combined mean paternity exclusion chance (MEC) was 0.999875 and that the combined discriminating power (DP) was 2.635 x 10(-11). The allelic distributions found in the Egyptian sample were significantly different at four loci from those found for an Austrian Caucasian population, at all nine loci from an African-American sample and at six of six loci from a Chinese sample. No evidence of linkage equilibrium between any of the co-amplified loci was found. Our results support that the combination of multiplex PCR and capillary electrophoresis can both save time and yield excellent results for paternity testing and stain analysis.     

Allele distribution data of nine short tandem repeat loci for Turkish population: D3S1358, vWA,FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820

Allele and genotype frequencies for the nine loci D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820 were determined for 310 unrelated Turkish individuals.     

Genetic variation of 15 STR loci (D3S1358, vWA, FGA, TH01, TPOX, CSF1PO, D5S818, D13S317, D7S820, D16S539, D2S1338, D8S1179, D21S11, D18S51, and D19S433) in populations of north and central Poland

Allele frequencies for 15 short tandem repeats (STRs) included in AmpFlSTR Profiler and AmpFlSTR SGM Plus kits were obtained from populations of Pomorze Gdanskie, Wielkopolska, Kujawy, Pomorze Zachodnie, Mazury and Mazowsze regions of Poland.     

Italian population data on thirteen short tandem repeat loci: HUMTH01, D21S11, D18S51, HUMVWFA31, HUMFIBRA,D8S1179, HUMTPOX,HUMCSF1PO,D16S539, D7S820, D13S317, D5S818, D3S1358

A population study on thirteen short tandem repeat (STR) loci was performed on 223 unrelated Italian Caucasians. The DNA was amplified by PCR. Separation and detection of the amplified STR fragments was carried out by use of 377 automated system (Applied Biosystems Division/Perkin Elmer). All loci meet Hardy–Wienberg expectations, and the data show only five departures out of seventy-eight pairwise locus tests which is close to expectations of 5% (5/78=6.4%). When correcting for multiple tests, there is little evidence for departures from expectations between loci. The combined Power of Exclusion for the thirteen STR loci is 0.99999270. The results demonstrate that these loci will be very useful for human identification in forensic cases in Italy.     

3个miniSTR基因座在湖南汉族人群中的遗传多态性

目的建立扩增片段小于120bp,包括D10S1248、D2S441和D1S16773个miniSTR基因座的复合扩增系统,并调查其在湖南汉族人群中的遗传多态性。方法采用不同荧光染料标记引物,通过PCR扩增,利用ABI 310遗传分析仪对186份无关个体血样进行3个miniSTR基因座片段长度分析。结果D10S1248、D2S441和D1S1677 miniSTR基因座均获得了清晰的基因分型结果,经对186名无关个体进行分析,分别检出9、7、7个等位基因和21、19、15种基因型,基因型分布符合Hardy-Weinberg平衡。3个基因座在湖南汉族人群的非父排除率和个体识别力分别为0．465、0．491、0．361和0．886、0．899、0．818。结论建立的3个miniSTR基因座扩增系统在DNA高度降解检材分析中具有较高的应用价值,并且在湖南汉族人群中具有较好的遗传多态性,可应用于个体识别和亲权鉴定。     

北京地区汉族人群6个STR基因座的遗传多态性

目的对北京地区汉族人群遗传数据进行调查研究。方法利用PCR自动化检测技术检测中国北京地区汉族人群D1S1656,D10S2325,D11S2368,D12S391,D14S1434及GATA198B05共6个STR基因座的遗传多态性,获得6个STR基因座的群体遗传学数据,评价其法医学应用价值。结果6个STR基因座的个体鉴别力（Discrimination power,DP）在0．9777-0．8769之间,多态性信息含量（Polymorphism information content,PIC）在0．6867-0．8801之间,杂合度（Heterozygosity,H）在0．7219～O．8684之间,非父排除率（Probability of paternity exclusion,PE）在0．4456-0．6793之间,累积个体鉴别力为0．99999997,累积非父排除率为0．995765192。结论6个STR基因座等位基因频率分布均匀,多态性高,适用于法医学亲子鉴定及个人识别,可作为现有基因座的补充。