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1.
Alleles and haplotypes frequencies for 10 Y-chromosome STR loci (DYS19, DYS385 I/II, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS438 and DYS439), included in the Y-Plex6 and Y-Plex5 kits were determined for a Tunisian population sample of 100 male individuals.  相似文献   

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Allele frequencies for the 15 short tandem repeats (STR) loci D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, CSF1PO, TH01, D16S539, D2S1338, TPOX D19S433 (AmpFLSTR Identifiler) were determined in a population sample of unrelated individuals living in eastern China.  相似文献   

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Allele frequencies for the 15 tetranucleotide short tandem repeat loci contained in the AmpFlSTR Identifiler kit were obtained from a population sample of 219 unrelated individuals born in the western part of Romania.  相似文献   

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Allele frequencies of 15 short tandem repeat loci included in the AmpFlSTR Identifiler kit (Applied Biosystems) were obtained from a sample set of unrelated individuals living in Belarus (n=176). For all loci, no deviation from Hardy-Weinberg equilibrium was found. Results were compared with data available for the Belarusian minority residing in northeastern Poland and for other Slavic populations. Statistically significant differences were observed between Belarusians and all compared populations. The values of heterozygosity, polymorphic information content (PIC), power of discrimination (PD), power of exclusion (PE), paternity index (PI) and matching probability (pM) were calculated.  相似文献   

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Nine Y-STR loci from the "minimal haplotype" (DYS19, DYS385a/b, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393) included in Y-STR Haplotype Reference Databases (YHRD) with 4 additional Y-STRs (DYS436, DYS437, DYS438, DYS439) were analyzed by PCR using duplex and Y-PLEX 12 kit, followed by automatic genotyping in a sample of 105 Tunisian males originating from Sfax region (south Tunisia). Allelic frequencies and gene diversities for each Y-STR locus were determined. The high haplotype diversity (0.9932) and discrimination capacity (0.7714) show the usefulness of these loci for human identification in forensic studies and paternity tests in Tunisia. The most common haplotype was shared by 4.7% (5 individuals) of the sample was only found in samples from the Tunisian population reported in YHRD. One private allele for DYS392 (allele 17) was discovered and duplications were observed for five loci (DYS19, DYS389I, DYS393, DYS437 and DYS439).  相似文献   

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Genetic polymorphisms of 15 STR loci in Chinese Hui population   总被引:2,自引:0,他引:2  
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Allele frequencies for 10 STRs included in the AmpFlSTR SGM Plus kit were determined in a population sample of 668 unrelated individuals living in western Poland. All loci met Hardy-Weinberg expectations. Exact tests disequilibrium analysis revealed two departures from independence out of 45 pairwise comparisons. The combined matching probability (MP) and power of exclusion (PE) for all 15 loci are 2.56 x 10(-13) and 0.99996, respectively.  相似文献   

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台湾汉族群体15个STR基因座的遗传多态性   总被引:2,自引:0,他引:2  
目的 为获得 15个基因座在台湾汉族群体中的遗传学数据 ,探究其在法医学检验中的应用价值。 方法 用ProwerPlex(r) 16System荧光标记试剂盒 (Promega公司 )检测 15个STR基因座的多态性。 结果 在 189例台湾汉族随机个体中 ,15个STR基因座分别检出 6、7、15、15、19、10、8、8、7、8、10、8、9、6、19个等位基因 ,各等位基因频率为 0 .0 0 2 6~ 0 .452 4。观察杂合度 (HO)为 0 .60 82~ 0 .92 61,期望杂合度 (HE)为 0 .610 3~ 0 .9162 ,多态信息含量 (PIC)为 0 .5491~ 0 .90 73 ,亲权排除率 (PE)为 0 .3 53 2~ 0 .82 64,个体识别率为 0 .60 91~ 0 .914 3。累积亲权排除率 (PE)为 0 .999999,累积个体识别率为 0 .999999999。 结论 该15个STR基因座具有很高的多态性 ,已可以满足大多数的亲权鉴定和法医学个人识别的需要  相似文献   

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广东省瑶族人群15个STR基因座的多态性调查   总被引:6,自引:0,他引:6  
目的调查广东省瑶族人群无关个体 15个STR基因座 (D3S135 8、TH0 1、D2 1S11、D18S5 1、PentaE、D5S818、D13S317、D7S82 0、D16S5 39、CSF1PO、PentaD、vWA、D8S1179、TPOX、FGA)的多态性 ,研究其在法医学检验中的应用价值。方法应用PowerplexTM16荧光标记复合扩增系统对 2 2 2例广东省瑶族无关个体血样DNA进行 15个STR基因座的复合扩增 ,用ABI 310 0遗传分析仪对扩增产物进行检测 ,用GeneScan、GenoTyper软件进行基因分型 ,统计计算 15个STR基因座的群体遗传学参数。结果PowerplexTM16荧光标记系统的 15个STR基因座在广东省瑶族人群的累积偶合率为 7 5 8× 10 - 17,三联体累积非父排除率为 0 999998,二联体累积非父排除率为 0 9996 6。结论本研究 15个STR基因座可满足广东省瑶族人群法医学的个体识别及亲权鉴定的需要。  相似文献   

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南方汉族、黎族人群15个STR基因座频率调查   总被引:24,自引:0,他引:24  
杨电  刘超  彭汝标  刘长晖  潘远义 《法医学杂志》2002,18(4):207-209,212
目的调查南方汉族、黎族人群无关个体的15个STR基因座(D8S1179、D21S11、D7S820、CSF1PO、D3S1358、TH01、D13S317、D16S539、D2S1338、D19S433、vWA、TPOX、D18S51、D5S818、FGA)多态性,研究其在法医学检验中的应用价值。方法应用AmpFlSTRIdentifilerTM荧光标记复合扩增系统对南方332例汉族、334例黎族无关个体血样DNA进行15个STR基因座的复合扩增,用ABI3100遗传分析仪对扩增产物进行检测,用GeneScan、GenoTyper软件进行基因分型,统计计算15个STR基因座的群体遗传学参数。结果IdentifilerTM荧光标记系统的15个STR基因座在南方汉族、黎族人群的累积偶合率分别为4.94×10-17、2.50×10-17,累积非父排除率分别为0.9999989、0.9999988。结论该15个STR基因座足可满足南方汉族、黎族法医学的个体识别及亲权鉴定的需要。  相似文献   

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Genetic polymorphisms of 15 STR loci in a Japanese population   总被引:5,自引:0,他引:5  
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目的为获得15个基因座在台湾汉族群体中的遗传学数据,探究其在法医学检验中的应用价值. 方法用ProwerPlex(r)16 System荧光标记试剂盒 (Promega公司)检测15个STR基因座的多态性. 结果在189例台湾汉族随机个体中,15个STR基因座分别检出6、7、15、15、19、10、8、8、7、8、10、8、9、6、19 个等位基因,各等位基因频率为0.002 6~0.452 4.观察杂合度(HO)为 0.608 2~0.926 1 ,期望杂合度(HE)为0.6103~0.916 2, 多态信息含量(PIC)为0.5491~0.9073,亲权排除率(PE)为0.353 2~0.826 4,个体识别率为0.609 1~0.914 3.累积亲权排除率(PE)为 0.999 999, 累积个体识别率为0.999 999 999. 结论该15个STR基因座具有很高的多态性,已可以满足大多数的亲权鉴定和法医学个人识别的需要.  相似文献   

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广西苗族人群15个STR基因座的多态性调查   总被引:9,自引:0,他引:9  
Liu C  Yang D  Liu CH 《法医学杂志》2003,19(4):204-206
目的调查广西苗族人群无关个体的15个STR基因座(D8S1179、D21S11、D7S820、CSF1PO、D3S1358、TH01、D13S317、D16S539、D2S1338、D19S433、vWA、TPOX、D18S51、D5S818、FGA)多态性,研究其在法医学检验中的应用价值。方法应用AmpFlSTRIdentifilerTM荧光标记复合扩增系统对274例广西苗族无关个体血样DNA进行15个STR基因座的复合扩增,用ABI3100遗传分析仪对扩增产物进行检测,用GeneScan、GenoTyper软件进行基因分型,统计计算15个STR基因座的群体遗传学参数。结果IdentifilerTM荧光标记系统的15个STR基因座在广西苗族人群的累积偶合率为5.04×10-17,累积非父排除率分别为0.9999993。结论该15个STR基因座可满足广西苗族人群法医学的个体识别及亲权鉴定的需要。  相似文献   

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