Evidence of a gene x environment interaction in the creation of victimization: results from a longitudinal sample of adolescents

A large body of research has revealed that aggressive personality traits and violent criminal behaviors are influenced by genetic factors. Surprisingly, however, no research has been devoted to investigating the potential genetic origins to adolescent victimization. In the current study, the authors address this gap in the literature by using data from the National Longitudinal Study of Adolescent Health (Add Health) to examine whether different variants of the dopamine D2 receptor gene (DRD2) are related to victimization, net of the effects of environmental measures. The results of the multivariate models revealed a significant gene X environment interaction in the creation of victimization for White males. Specifically, DRD2 interacted with delinquent peers to predict victimization. The authors discuss the implications of these findings.     

Genetic risk factors correlate with county-level violent crime rates and collective disadvantage

Purpose

Social scientists have a rich tradition of uncovering the neighborhood, structural, and ecological correlates of human behavior. Results from this body of evidence have revealed that living in disadvantaged communities portends myriad negative outcomes, including antisocial behaviors. Though it has long been argued that associations between neighborhood factors and individual-level outcomes may, at least partially, reflect genetic selection, a paucity of research has empirically investigated this possibility.

Methods

The current study examined whether known genetic risk factors for antisocial behavior were predictive of exposure to disadvantage and violent crime measured at the county level. Drawing on genotypic data from the National Longitudinal Study of Adolescent Health, a dopamine risk scale was created based on respondents’ genotypes for DAT1, DRD2, and DRD4. County-level disadvantage was measured via Census data and violent crime rates were measured via the FBI’s Uniform Crime Reports.

Results

Findings revealed that individuals with a greater number of dopamine risk alleles were more likely to live in a disadvantaged county and were more likely to live in a county with higher violent crime rates.     

The sent-down youth of China: The role of family origin in the risk of departure to and return from the countryside

Between 1967 and 1978, over 17million urban youths in China systematically migrated to the rural countryside in a massive relocation movement known as the Sent-Down Movement. The youths who relocated—some by choice, though many forcibly—were part of a grand scheme envisioned by the then ruling Communist Party leader, Mao Zedong, who sought to reeducate urban youth by having them live and labor amongst their rural compatriots. Known as the “sent down youth”, these youths' experiences and struggles of moving to and returning from the countryside offer considerable insight into the ideological importance of family origins. Most notably, the revolutionary movement which swept over China at the height of the sent-down movement in the late 1960s reversed the hierarchical order of society; individuals with higher family origins were now criminalized making them prime targets for relocation to the countryside. In this quantitative analysis, I examine the relationship between family origins and the risk of departure to and return from the countryside for urban youth, using a unique longitudinal retrospective dataset, Life Histories and Social Change in Contemporary China. I analyze how this relationship plays out not only during the height of the movement, but throughout a more expansive time frame under which youths were reportedly sent-down (1957 to 1980). Through discrete-time survival analysis, I estimate that urban youths from higher family origins (rich peasant and landowner classes) experienced a greater risk for being sent-down versus their counterparts from lower family origins. Most interestingly, youths of higher family origins also experienced a lower risk for returning from the countryside; one interpretation of this finding is that even after spending time in the countryside in the pursuit of absolving themselves of their higher family origins, the stigma attached to their higher family origins persisted.     

Low‐Risk Youths Referred to Pima County Juvenile Court Center Detention Intake: Needs,Detention, and Recidivism

Delinquent youths who were low risk to re‐offend were the subject of this study. It was hypothesized that these youths would have high levels of need (e.g., mental illness) and that detention would lead to increased recidivism. Demographic and social factors, delinquency history, and recidivism data were analyzed, producing four major findings: low‐risk youths have high needs, low‐risk youths recidivate at high rates, unaddressed needs increase the likelihood of detention and recidivism, and behavioral health needs were among the strongest predictors of recidivism. The factors that lead to recidivism are discussed, and suggestions for improving outcomes are also presented.     

Gender differences in risk for intimate partner violence among South African adults

Despite a high prevalence of intimate partner violence in South Africa, few epidemiological studies have assessed individual risk factors and differential vulnerability by gender. This study seeks to analyze gender differences in risk for intimate partner violence victimization and perpetration according to childhood and adult risk factors in a national sample of South African men and women. Using data from the cross-sectional, nationally representative South Africa Stress and Health Study, the authors examine data from 1,715 currently married or cohabiting adults on reporting of intimate partner violence. Our analysis include (a) demographic factors, (b) early life risk factors (including exposure to childhood physical abuse, witnessing parental violence, parental closeness, and early onset DSM-IV disorders), and (c) adult risk factors (including experiencing the death of a child and episodes of DSM-IV disorders after age 20). Although prevalence rates of intimate partner violence are high among both genders, women are significantly more likely than men to report being victimized (29.3% vs. 20.9%). Rates of perpetrating violence are similar for women and men (25.2% and 26.5%, respectively). Men are more likely to report predictive factors for perpetration, whereas women are more likely to report predictors for victimization. Common risk factors among men and women reporting perpetration include exposure to childhood physical abuse, witnessing parental violence, and adult onset alcohol abuse/dependence. However, risk factors in male perpetrators are more likely to include cohabitation, low income, and early and adult-onset mood disorders, whereas risk factors in female perpetrators include low educational attainment and early onset alcohol abuse/dependence. The single common risk factor for male and female victims of partner violence is witnessing parental violence. Additional risk factors for male victims are low income and lack of closeness to a primary female caregiver, whereas additional risk factors for female victims are low educational attainment, childhood physical abuse, and adult onset alcohol abuse/dependence and intermittent explosive disorder. Intimate partner violence is a significant public health issue in South Africa, strongly linked to intergenerational cycling of violence and risk exposure across the life course. These findings indicate that gender differences in risk and common predictive factors, such as alcohol abuse and exposure to childhood violence, should inform the design of future violence-prevention programs and policies.     

Do individual factors and neighborhood context explain ethnic differences in juvenile delinquency?

Individually measured factors and neighborhood context were related to juvenile delinquency in a community sample of 506 urban, public-school boys. Neighborhood context was measured with an objective, census-based score that classified neighborhoods as underclass or not underclass. When African American youths and white youths were compared without regard to neighborhood context, African American youths were more frequently and more seriously delinquent than white youths. When African American youths didnot live in underclass neighborhoods, their delinquent behavior was similar to that of the white youths. Hierarchical multiple regression analyses showed that boys' hyperactivity and parental supervision were the strongest correlates of delinquency. Single-parent status and poverty/welfare use were not related to delinquent behavior. Once individually measured factors were accounted for, residence in underclass neighborhoods was significantly related to delinquent behavior while ethnicity was not. This study points to the importance of including the neighborhood context when addressing the social problems of African American youths.     

EXAMINING THE GENETIC UNDERPINNINGS TO MOFFITT'S DEVELOPMENTAL TAXONOMY: A BEHAVIORAL GENETIC ANALYSIS*

In recent years, criminological research has observed an increase in studies examining different offending trajectories. Much of this research has been guided by Moffitt's (1993) developmental taxonomy of life‐course persistent offenders, adolescence‐limited offenders, and abstainers. Moffitt (1993) argued that the etiologies of these different pathways could be traced to several biosocial factors, including perhaps genetic factors. To date, research has failed to address this possibility directly. The current study addressed this gap in the literature by examining the extent to which genetic factors explain variance in different offending patterns. Analysis of sibling pairs (N = 2,284; ages spanned between 11 and 27 years) drawn from the National Longitudinal Study of Adolescent Health (Add Health) revealed that genetic factors contributed significantly to being classified in each of the different offending patterns. Specifically, genetic factors explained between 56 and 70 percent of the variance in being classified as a life‐course persistent offender across different coding strategies, 35 percent of the variance in being classified as an adolescence‐limited offender, and 56 percent of the variance in being classified as an abstainer. We discuss the importance of integrating genetics into future studies examining offending trajectories.     

Evidence of a gene × environment interaction between perceived prejudice and MAOA genotype in the prediction of criminal arrests

Purpose

The current study builds on a large body of research that has revealed that both genetic and environmental factors contribute to the development of antisocial behaviors. While a number of studies have indicated that stressful environments interact with specific genetic polymorphisms to create antisocial phenotypes, studies have not yet examined whether perceived prejudice and specific genetic polymorphisms combine together to predict criminal arrests over the life course.

Methods

The current study builds on the existing gene × environment literature by using data from the National Longitudinal Study of Adolescent Health (Add Health) to examine the effects of MAOA and perceived prejudice on the probability of being arrested.

Results

The results of the multivariate models reveal a statistically significant gene × environment interaction between MAOA and perceived prejudice in the prediction of arrest for males.

Conclusions

The results indicate that the presence of both perceived prejudice and MAOA increase the likelihood of being arrested. The implications of these results are discussed and limitations are noted.     

Genetic and Environmental Overlap between Low Self-Control and Delinquency

Low self-control has emerged as a consistent and strong predictor of antisocial and delinquent behaviors. Using the twin subsample of the National Longitudinal Study of Adolescent Health (Add Health), genetic analyses were conducted to examine the genetic and environmental contributions to low self-control and offending as well as to their relationship with one another. The results revealed that low self-control and criminal behaviors are influenced by genetic and nonshared environmental factors with the effects of shared environmental factors being negligible. In addition, the co-variation between low self-control and criminal behaviors appears to be largely due to common genetic and nonshared environmental factors operating on both phenotypes. The implications of these findings on the current understanding of Gottfredson and Hirschi??s general theory of crime are discussed.     

Genetic influences on the stability of low self-control: Results from a longitudinal sample of twins

Gottfredson and Hirschi's theory contained two propositions that have been the source of an emerging line of empirical scrutiny. First, according to the general theory of crime, levels of self-control are largely determined by parental management techniques and not by biogenic factors. Second, Gottfredson and Hirschi argued that low self-control should remain relatively stable over the life course. Data from twins drawn from the National Longitudinal Study of Adolescent Health were used to test these two hypotheses. The results of univariate model-fitting techniques revealed that genetic factors accounted for between 52 and 64 percent of the variance in low self-control, with the remaining variance attributable to the nonshared environment. Further, low self-control was stable over a two-year time period (r = .64). Bivariate Cholesky decomposition models indicated that the stability of self-control was determined almost exclusively by genetic factors, and that genetic factors also explained a moderate amount of change in self-control.     

The Prediction of Young Homicide and Violent Offenders

Aim was to investigate a range of potentially modifiable risk factors for boys in late childhood for later violence and homicide convictions. Boys from the Pittsburgh Youth Study (N = 1,517) were measured through self-reports and official records in late childhood (ages 11–13) on a large number of potentially modifiable risk factors, and were followed up in juvenile and adult criminal records in terms of violence and homicide. Predictors of conviction for homicide largely overlapped with predictors of conviction for violence. Twenty three out of 28 possible risk factors significantly predicted later violence convictions. Regression analysis identified four significant modifiable risk factors in late childhood for any violent offenders: physical abuse, parental stress, bad friends and low school motivation. The higher the number of early risk factors, the higher the probability of later conviction for violent offenses including homicide. The discussion focus on single-, and multi-modal interventions in late childhood to reduce later violence and possibly homicide.     

Genetic and environmental influences underlying the relationship between low self-control and substance use

Purpose

The current study seeks to examine the relationship between low self-control and cigarette smoking, alcohol use, and marijuana use in adolescence and adulthood using behavioral genetic methodology.

Methods

Using a subsample of twin pairs from the National Longitudinal Study of Adolescent Health (Add Health), the current study estimates the genetic and environmental overlap between low self-control and substance use (or problems associated with substance use) across four waves of data collection.

Results

The overall pattern of results suggests that genetic factors explain a moderate proportion of the variance in low self-control and substance use in both adolescence and adulthood. Furthermore, bivariate genetic analyses reveal that the correlation between low self-control and substance use is due, for the most part, to common genetic and nonshared environmental factors.

Conclusions

The current study adds to a growing body of biosocial research on self-control and its relationship to criminal and analogous behaviors. The implications of our findings for the general theory of crime are discussed.     

The Right to Counsel in Juvenile Court: The Conundrum of Attorneys as an Aggravating Factor at Disposition

In re Gault provided procedural safeguards in juvenile courts, including the right to counsel. Decades later, judges continue to resist appointing lawyers. And, when they do appoint counsel, lawyers appear to be an aggravating factor when judges sentence youths. In 1995, Minnesota enacted law reforms, including mandatory appointment of counsel. As a cost‐saving strategy, the law also converted most misdemeanors into status offenses and restricted judges’ sentencing authority in order to deny juveniles a right to counsel. This study compares how juvenile courts processed 30,270 youths in 1994—the year before the changes—with how they processed 39,369 youths in 1999 after the amendments. We assess changes in appointment of counsel and their impact on sentencing practices. We report inconsistent judicial compliance with the mandate to appoint counsel and a positive decrease in the number of youths removed from home.     

Patterns of Risk and Protective Factors in the Intergenerational Cycle of Maltreatment

This study investigates the continuation and discontinuation of the intergenerational transmission of child maltreatment within the first 13 months of the child’s life. Differences in risk factors and parenting styles between families who initiate (Initiators), maintain (Maintainers) or break (Cycle Breakers) the intergenerational cycle of child maltreatment are explored in comparison to control families (Controls). One hundred and three Health Visitors were trained to assess risk factors and parenting styles of 4,351 families, at both 4–6 weeks and 3–5 months after birth. Maintainers, Initiators and Cycle Breakers had a significantly higher prevalence for the majority of risk factors and poor parenting styles than Controls. Protective factors of financial solvency and social support distinguished Cycle Breakers from Maintainers and Initiators. Therefore, it is the presence of protective factors that distinguish Cycle Breakers from families who were referred to Child Protection professionals in the first year after birth. A conceptual, hierarchical model that considers history of abuse, risk and protective factors, in turn, is proposed to assess families for the potential of child maltreatment.     

The Relationship between Self-Control in Adolescence and Social Consequences in Adulthood: Assessing the Influence of Genetic Confounds

Purpose

Assess the relationship between levels of self-control in adolescence and a variety of later-life outcomes and evaluate the confounding effects of genetic factors.

Methods

The current study employed data from the National Longitudinal Study of Adolescent Health (Add Health) and examined whether levels of self-control in adolescence are related to economic, educational, employment, health, relationship and family, and behavioral outcomes in adulthood using DeFries-Fulker regression-based analyses.

Results

Analyses employing non-genetically sensitive methods indicated robust associations between self-control and various social consequences. After estimating genetically-sensitive analyses, however, many associations were no longer significant. Those associations which remained significant were in the reversed direction relative to the non-genetically sensitive models. Additionally, further analyses indicated that some of the remaining significant associations were influenced by nonshared genetic effects.

Conclusions

The findings indicate that even after controlling for the effect of genetic factors, levels of self-control are associated with differences in a variety of social outcomes. However, given the reduction in the number of significant associations and reversal of associations in the genetically sensitive models, analyses of the social consequences of low self-control which do not account for the effect of genetic factors are likely misspecified.     

Deviant identity,negative self-feelings,and decreases in deviant behavior: The moderating influence of conventional social bonding

Abstract

Informed by Kaplan's general theory of deviant behavior it was hypothesized that adolescents characterized by deviant identities who developed negative self-feelings would decrease deviant behavior over time if the youths were bonded to the conventional social order but not if the youths were not bonded to the conventional social order. For adolescents not characterized by deviant identities, the development of negative self-feelings would increase deviant behavior over time regardless of the level of conventional social bonding.

The hypotheses were explored using data from youth (n=1019) tested during early adolescence and re-tested 3 years later. Ordinary least square regression models estimated the effects of negative self-feelings on later deviant behaviors controlling for earlier deviant behavior, gender, race/ethnicity, and father's education. The model was estimated separately for each of four subgroups: deviant identity/high social bonding; deviant identity/low social bonding; non-deviant identity/high social bonding; and non-deviant identity/low social bonding.

As hypothesized, negative self-feelings anticipated significant decreases in deviant behavior for the deviant identity/high social bonding group, but were unrelated to deviant behavior in the deviant identity/low social bonding group; and negative self-feelings anticipated increased deviant behavior in the two non-deviant identity groups regardless of the level of social bonding.     

The effects of an experimental intensive juvenile probation program on self-reported delinquency and drug use

In the late 1990s Ventura County, California, USA, implemented the South Oxnard Challenge Project (SOCP), designed to provide intensive, multi-agency services to youth on probation. SOCP built their program guided by Clear’s “corrections of place” model, which argued that community corrections could decrease offender risk by focusing on restorative principles rather than on coercion. SOCP was designed as a randomized experiment, comparing youths in the experimental group with those on routine probation. Researchers interviewed youths in both the experimental and control groups 1 year after random assignment. This article reports on self-reported crime and drug use, finding few significant differences across groups. Specifically, we find that SOCP youths were significantly more likely to indicate that they had committed a violent crime generally, although a majority of both groups indicated they had done so. We found that those in SOCP who robbed people also did so significantly more often than did the comparison group. In the control group, youths reported committing homicide significantly more often, but this was a rare event. Among those youths who reported taking part in gang or posse fights, those in the control group did so significantly more often. Finally, youths in the control group were significantly more likely to have used ecstasy on more days during the previous month than were those in the SOCP.

Can Callous-Unemotional Traits and Aggression Identify Children at High-Risk of Anti-Social Behavior in a Low Socioeconomic Group?

Frick et al. (2005) proposed that Callous-Unemotional (CU) traits may be an important personality dimension associated with youth offending. The goal of the present study was to examine whether CU traits were associated with risk factors for offending in a low SES sample of children aged 10 years to 11 years in New Zealand. Two subgroups were identified: one high (High-CU/Agg group) and one low (Low-CU/Agg group) on CU traits and aggression. Results showed that scores for the High-CU/Agg group were significantly worse compared to the Low-CU/Agg group on a range of measures including stress management, caregiver criminal convictions, and dysfunctional parenting. However, analyses revealed that the measure of aggression accounted for more unique variance compared to CU traits. Further research is needed with youths from low SES communities to develop a more robust profile of potential youth offenders.     

De Novo Advanced Adult‐Onset Offending: New Evidence from a Population of Federal Correctional Clients

Adult antisocial behavior is almost always predated by delinquency during childhood or adolescence; however, there is also evidence of adult‐onset criminal offending. This study examined this controversial subgroup of offenders using self‐reported and official data from a total population of federal correctional clients selected from the Midwestern United States. Difference of means t‐tests, chi‐square tests, and logistic regression models found that 11.7% of clients had an adult onset of offending and 2.7% of clients (n = 23) had an onset occurring at age 60 years or older. This group—introduced as de novo advanced adult‐onset offenders—had high socioeconomic status, mixed evidence of adverse childhood experiences, and virtually no usage of drugs with the exception of alcohol. These offenders were primarily convicted of social security and white‐collar crimes and evinced remarkably low psychopathology and criminal risk. More research is needed to replicate the phenomenon of de novo advanced adult‐onset offending.     

Genetic variability of RyR2 and CASQ2 genes in an Asian population

We analyzed the coding regions of the cardiac calcium-handling genes, ryanodine receptor 2 (RyR2) and calsequestrin 2 (CASQ2) for genetic variants in a healthy Chinese population (n = 95) and in a cohort of 28 sudden unexplained death victims. Mutations in RyR2 and CASQ2 have been shown to alter calcium homeostasis during excitation–contraction coupling and predispose individuals to fatal cardiac arrhythmias. The genetic screening was accomplished by denaturing high-performance liquid chromatography and DNA sequencing methods. Genetic analysis revealed the following non-synonymous genetic variations: two reported RyR2 polymorphisms; 5654G>A (G1885E) and 5656G>A (G1886S), two reported CASQ2 polymorphisms; 196A>G (T66A) and 226G>A (V76M) and one novel CASQ2 mutation; 529G>C (E177Q). The functional significance of the novel CASQ2 mutation has not been evaluated and characterized. This study shows that multiple genetic variations of the RyR2 and CASQ2 genes exist in the two study populations. The inter-individual genetic variability may underlie the different susceptibility of individuals to developing ventricular tachycardia. The research results will be valuable for which future work involving clinical and forensic samples can be based upon to distinguish potential disease-associated mutations from common polymorphisms.