Calculation of likelihood ratio y/x in diagnosis of paternity using computer methods.

A new computational method using a Monte Carlo technique is described for the calculation of plausibility of paternity in blood group systems. In this study gene frequencies of a blood group system are simulated by the range of the seven digit random numbers. By using a Monte Carlo method, four random numbers are generated and converted into paternal and maternal genotypes. Then the genotype of the child is determined according to the law of inheritance, and finally genotypes of the father, mother and child are converted into phenotypes. Repeating this process more than one hundred thousand times, the phenotypic frequencies of child-mother-father combinations (trio) and the likelihood ratio of paternity in any blood group system are calculated for all phenotypic combinations of the trios. This method is much easier than methods reported previously, and is sufficiently accurate.     

The identification of antigens of systems AB0, GM,and haptoglobin (HP) phenotypes in mixed bloodstains of human and domestic goose

The traditional methods of investigations according to systems AB0, Gm and Hp were used to define the serological specificity of home gooses' blood. The experimental examinations' results related with mixed bloodstains of man and home gooses are described. A possibility is demonstrated to identify the blood group factors of man in bloodstains with admixture of home-goose blood.     

Use of deoxyribonucleic acid (DNA) fingerprints for identity determination: comparison with traditional paternity testing methods--Part I

A study involving comparison of the deoxyribonucleic acid (DNA) finger-printing test with traditional methods used for paternity testing is presented. Samples from 191 cases were tested for a series of blood group and polymorphic protein markers. DNA "fingerprints" were then obtained for all samples using the multilocus probes 33.6 and 33.15. The results of DNA fingerprinting correlated well with those of traditional methods and proved to be informative in cases where traditional methods yielded inconclusive or insufficient results.     

Phenolphthalein False‐Positive Reactions from Legume Root Nodules

Presumptive tests for blood play a critical role in the examination of physical evidence and in the determination of subsequent analysis. The catalytic power of hemoglobin allows colorimetric reactions employing phenolphthalein (Kastle‐Meyer test) to indicate “whether” blood is present. Consequently, DNA profiles extracted from phenolphthalein‐positive stains are presumed to be from blood on the evidentiary item and can lead to the identification of “whose” blood is present. Crushed nodules from a variety of legumes yielded phenolphthalein false‐positive reactions that were indistinguishable from true bloodstains both in color quality and in developmental time frame. Clothing and other materials stained by nodules also yielded phenolphthalein false‐positive reactivity for several years after nodule exposure. Nodules from leguminous plants contain a protein (leghemoglobin) which is structurally and functionally similar to hemoglobin. Testing of purified leghemoglobin confirmed this protein as a source of phenolphthalein reactivity. A scenario is presented showing how the presence of leghemoglobin from nodule staining can mislead investigators.     

Microbiota Composition and Pulmonary Surfactant Protein Expression as Markers of Death by Drowning

Pathological diagnosis of drowning remains a challenge for forensic science, because of a lack of pathognomonic findings. We analyzed microbiota and surfactant protein in the lungs for a novel diagnosis of drowning. All rats were divided into drowning, postmortem submersion, and control groups. The water, lungs, closed organs (kidney and liver), and cardiac blood in rats were assayed by targeting 16S ribosomal RNA of Miseq sequencing. Lung samples were analyzed by immunohistochemical staining for surfactant protein A. The closed organs and cardiac blood of drowned group have a lot of aquatic microbes, which have not been detected in postmortem submersion group. Furthermore, intra‐alveolar granular staining of surfactant protein A (SP‐A) was severely observed in the drowned group than the postmortem submersion and control groups. The findings suggested that the presence of aquatic microbiota in the closed organs and increased expression of SP‐A could be markers for a diagnosis of drowning.     

Preliminary report on a new method of human age estimation from single adult teeth.

A total of 317 upper and lower third molars were randomly divided into working and control samples and used to estimate chronological age employing a method which combined multiple regression analysis of data from Gustafson's and Maples's scoring system, direct morphological measurements obtained with a Kontron image analysis system and logarithmic data transformation. The standard errors of estimate were 2.4-6.8 years in the working sample and 1.9-7.5 years when the derived formulae were tested on the control sample, respectively. Compared to previous studies, this method provides a smaller standard error of estimate from a single molar tooth. The method is presently being tested on other tooth categories, like premolars, canines and other types of molars.     

Using sensitive data to prevent discrimination by artificial intelligence: Does the GDPR need a new exception?

Organisations can use artificial intelligence to make decisions about people for a variety of reasons, for instance, to select the best candidates from many job applications. However, AI systems can have discriminatory effects when used for decision-making. To illustrate, an AI system could reject applications of people with a certain ethnicity, while the organisation did not plan such ethnicity discrimination. But in Europe, an organisation runs into a problem when it wants to assess whether its AI system accidentally discriminates based on ethnicity: the organisation may not know the applicants’ ethnicity. In principle, the GDPR bans the use of certain ‘special categories of data’ (sometimes called ‘sensitive data’), which include data on ethnicity, religion, and sexual preference. The proposal for an AI Act of the European Commission includes a provision that would enable organisations to use special categories of data for auditing their AI systems. This paper asks whether the GDPR's rules on special categories of personal data hinder the prevention of AI-driven discrimination. We argue that the GDPR does prohibit such use of special category data in many circumstances. We also map out the arguments for and against creating an exception to the GDPR's ban on using special categories of personal data, to enable preventing discrimination by AI systems. The paper discusses European law, but the paper can be relevant outside Europe too, as many policymakers in the world grapple with the tension between privacy and non-discrimination policy.     

How Do Police Respond to Stalking? An Examination of the Risk Management Strategies and Tactics Used in a Specialized Anti-Stalking Law Enforcement Unit

How do police respond to and manage complaints of stalking? To answer this question, we conducted a 3-phase study. First, we reviewed the literature to identify risk management tactics used to combat stalking. Second, we asked a group of police officers to review those tactics for completeness and group them into categories reflecting more general risk management strategies. The result was 22 categories of strategies. Finally, we used qualitative methods to evaluate the files of 32 cases referred to the specialized anti-stalking unit of a metropolitan police department. We coded specific risk management tactics and strategies used by police. Results indicated that a median number of 19 specific tactics from 7 general strategies were used to manage risk. Also, the implementation of strategies and tactics reflected specific characteristics of the cases (e.g., perpetrator risk factors, victim vulnerability factors), suggesting that the risk management decisions made by police were indeed strategic in nature. Qualitative analyses indicated that some of the strategies and tactics were more effective than others. We discuss how these findings can be used to understand and use stalking risk management more generally, as well as improve research on the efficacy of risk assessment and management for stalking.     

Age-related changes in the nervous apparatus of the blood vessels in the brain and spinal cord

This work was designed to study changes in the nervous apparatus of the blood vessels in the brain and spinal cord with a view to developing methods for the determination of the biological age in man. Pial and intramedullary vascular systems of the brain and spinal cord were examined in different periods of postnatal ontogenesis (between the age of 1 and 90 years) using histological, fluorescent-histochemical, and immunohistochemical methods as well as by ink injections into the blood vessels, scanning and transmission electron microscopy. The data obtained on the age-related rearrangement of the nervous apparatus of the arterial vessels in the brain and spinal cord have not only theoretical significance but can also be used for the solution of practical problems encountered in the practical work of forensic medical experts.     

Amphetamine derivative related deaths

Amphetamine its methylendioxy (methylendioxyamphetamine methylenedioxymethylamphetamine, methylenedioxyethylamphetamine) and methoxy derivatives (p-methoxyamphetamine and p-methoxymethylamphetamine) are widely abused in Spanish society. We present here the results of a systematic study of all cases of deaths brought to the attention of the Madrid department of the Instituto Nacional de Toxicologia from 1993 to 1995 in which some of these drugs have been found in the cadaveric blood. The cases were divided into three categories: amphetamine and derivatives, amphetamines and alcohol, amphetamines and other drugs. Data on age, sex, clinical symptoms, morphological findings, circumstances of death, when known, and concentration of amphetamine derivatives, alcohol and other drugs in blood are given for each group. The information provided here may prove to be useful for the forensic interpretation of deaths which are directly or indirectly related to abuse of amphetamine derivatives.     

Understanding the causes of disproportionate minority contact: Results of focus group discussions

Using a qualitative methods approach, this study explored the causes of disproportionate minority contact (DMC) from the clientele perspective. The data were collected via focus group discussions and in-depth interviews with the stakeholders, to examine the causes of disproportionate minority contact and determine the needs of the community. The results revealed that the causes and mechanisms of DMC were multi-faceted and complex. These causes could be classified into six categories: system, social, family/parental, educational, individual, and economic factors. Each one of these categories played a significant role in contributing to the final outcome of DMC. A significant theme that emerged from the results drew attention to the fact that in order to bring about any change and reduce DMC, all sectors of the society—law enforcement system, juvenile justice system, families, neighborhoods, and parents needed to work together and take greater responsibilities in assuring that juveniles stay out of trouble. The results also underscored that educating the communities on the existing resources for children and families would prove advantageous in reducing DMC.     

压力循环技术用于人指甲DNA提取及方法学评价

目的将压力循环技术（PCT）用于指甲DNA提取,并对方法学进行评价。方法收集10份人指甲样本,剪碎约为1mm×1mm大小,采用10%漂白粉水,10%SDS,10%漂白粉水,无菌水清洗样本。10份样本各分成两组,1组用压力循环技术处理,另1组不作处理,提取DNA经复合扩增并进行STR分型检测,用于评价压力循环技术的作用。取5份指甲样本用血浸泡,5份用去离子水浸泡,之后采用上述清洗方法各清洗1-3次,收集各次清洗用的无菌水提取DNA,经STR分型检测,用于评价清洗对去除外源性DNA的效果。结果 10份经压力循环技术处理的样本中有7例比相应未经处理样本DNA提取量更高,但两组进行统计学处理,差异不具有统计学意义（P〉0.05）;两组样本中提取DNA含量在0.026 ng以上的样本均得到完整的STR分型,与相应口腔拭子样本对照准确无误。血污染和非血污染样本清洗二次以上,均可避免外源性DNA的污染。结论使用压力循环技术并配合本文清洗方法,可有效提高人指甲DNA的提取效率,并避免外源性生物DNA的干扰,保证DNA分型结果的准确。     

Prohibited artificial intelligence practices in the proposed EU artificial intelligence act (AIA)

Artificial intelligence (AI) now forms a more and more important part of human lives. After years focussed on the development of AI, the initial hype about its many expected benefits has gradually given way to rising ethical concerns about its inherent risks and dangers. Efforts to confront and contain the most serious risks related to AI have now prompted a number of legislative or regulatory proposals at the national, regional and global level. One of the most comprehensive regulatory initiatives is the European Union's proposal for an Artificial Intelligence Act (AIA), which was released in April 2021 with a view towards establishing a legal framework for trustworthy AI. To this end, the draft AIA pursues a proportionate horizontal and risk-based regulatory approach to AI, broadly classifying AI into the categories of unacceptable risks, high risks and low or minimal risks. The unacceptable risks are those that are deemed to contravene European Union values, and therefore, they are considered to be ‘prohibited AI practices’ by Article 5 AIA. The prohibited AI practices are classified into four categories, namely 1) AI systems deploying subliminal techniques; 2) AI practices exploiting vulnerabilities; 3) social scoring systems; and 4) ‘real-time’ remote biometric identification systems. The proposed regulatory approach, however, appears problematic given the four categories’ inherent interrelatedness and the numerous possibilities for their mutual combination and entwinement. It is also problematic from the perspective of the human mind, as each of the four categories alone allows for the manipulation of human thought and behaviour, thereby endangering freedom of thought and other fundamental rights. In the context of the proposed AIA, both aspects give rise to unknown and unsolved conundrums that create difficult regulatory challenges that raise the necessity to also look at the wider implications of these technologies for the entire legal system. As these conundrums often find their expression in paradoxes and oxymora, this article calls for a wider interdisciplinary debate and advocates a different regulatory strategy using these concepts to transcend the limitations inherent in dualistic or dichotomous modes of legal thinking.     

Chromosome heteromorphisms and paternity testing

Most of the blood group systems have now been applied to paternity investigations. In a complicated case, an alleged father not excluded with blood group testing, could be excluded with only chromosome heteromorphisms. Chromosome heteromorphisms are inherited from parents to offspring as simple Mendelian laws. The authors' paternity testing is presented with the help of chromosome heteromorphism analysis.     

Forensic Mental Health Clinical Evaluation: An Analysis of Interstate and Intersystemic Differences

Forensic mental health evaluation systems have undergone major changes during the past two decades, and the variability of service delivery systems across states is significant. We compared assessments of competence to stand trial and criminal responsibility in three states with different systems for forensic mental health evaluations: Michigan, Ohio, and Virginia. Although all three states use comparable legal criteria to judge competence and criminal responsibility, we found large, statistically significant differences among the states in the proportion of defendants referred for evaluation who were assessed as incompetent or not criminally responsible. In addition, significant differences were found in the diagnostic and offense categories of defendants referred for evaluation. Our findings suggest that the structure of a system for providing forensic evaluation services may significantly affect both the group of individuals referred for evaluation as well as evaluation outcome.     

Toward an agenda for reform of justice and mental health systems interactions

This article presents an agenda for reform of the justice and mental health systems interactions, which includes policy, management, and research strategies related to the systemic and interorganizational issues facing the two systems. The strategies are divided into six major categories: (a) base decisions, procedures, and policies on empirical data; (b) improve communications between system; (c) ensure dignity and respect are afforded all individuals involved in both systems; (d) ensure the availability and delivery of mental health services and treatment prorams; (e) inform others about issues related to the intereactions of the justice and mental health systems; and (f) periodically review and reformulate policies, management strategies, and research efforts for improving systems interactions. The article also presents a summary of the problems and possible goals associated with mental health and justice systems interactions. The summaries as well as the agenda are based on the results of a symposiuum attended by practitioners and scholars in the justice and mental health fields.     

合成大麻素检验方法研究进展

近年合成大麻素类物质(synthetic cannabinoids,SCs)的危害及滥用引起社会广泛关注,它们不仅具有类似天然大麻的致幻性,还有更强的副作用,包括潜在的神经精神毒性,严重影响人类身心健康。因此,国内外研究人员对合成大麻素及其代谢物的检验方法进行了相关研究。本文主要介绍了SCs的生理药理作用、主要分类等,对其检验方法研究进展进行了综述与展望,探讨了各检验方法的应用范围与选择依据,以期为SCs相关案件的检验鉴定提供参考。     

Crime scene investigations using portable,non-destructive space exploration technology

The National Institute of Justice (NIJ) and the National Aeronautics and Space Administration's (NASAs) Goddard Space Flight Center (GSFC) have teamed up to explore the use of NASA developed technologies to help criminal justice agencies and professionals solve crimes. The objective of the program is to produce instruments and communication networks that have application within both NASA's space program and NIJ programs with state and local forensic laboratories. A working group of NASA scientists and law enforcement professionals has been established to develop and implement a feasibility demonstration program. Specifically, the group has focused its efforts on identifying gunpowder and primer residue, blood, and semen at crime scenes. Non-destructive elemental composition identification methods are carried out using portable X-ray fluorescence (XRF) systems. These systems are similar to those being developed for planetary exploration programs. A breadboard model of a portable XRF system has been constructed for these tests using room temperature silicon and cadmium-zinc telluride (CZT) detectors. Preliminary tests have been completed with gunshot residue (GSR), blood-spatter and semen samples. Many of the element composition lines have been identified. Studies to determine the minimum detectable limits needed for the analyses of GSR, blood and semen in the crime scene environment have been initiated and preliminary results obtained. Furthermore, a database made up of the inorganic composition of GSR is being developed. Using data obtained from the open literature of the elemental composition of barium (Ba) and antimony (Sb) in handswipes of GSR, we believe that there may be a unique GSR signature based on the Sb to Ba ratio.     

交通事故轮胎鉴定概述

轮胎鉴定是指涉及事故车辆的轮胎相关的鉴定项目,是交通事故技术鉴定中的重要项目之一,一般可分为轮胎痕迹鉴定和轮胎损坏情况及其与事故关系鉴定两种.本文着重论述了交通事故技术鉴定中上述两种轮胎鉴定的定义、鉴定步骤、鉴定方法,并通过典型案例来全面解读轮胎鉴定的具体鉴定过程.     

Comparison of fingernail ridge patterns of monozygotic twins

The ridge patterns on the fingernails of corresponding fingers of a pair of twins were compared microscopically and found to be readily distinguishable from one another. Based on blood grouping in six blood group systems (ABO, Rhesus, Ss, Duffy, Kidd, and Kell), the probability that the twins were monozygotic was calculated to be 89.1%.