Antibodies in threshold dilutions of group-specific immune sera and their forensic medical significance

Antibodies of nonadsorbed antisera are specific and under certain conditions can react with nonhomologous antigens. This assumption is scientifically based and experimentally confirmed. This property of antibodies opens new vistas for solving theoretical and practical tasks in medicine and biology with regard to the antigen-antibody tests. A technology of making highly effective group specific immunoreagents for forensic medical institutions and blood transfusion service has been created. The technology of immunoreagent making is patented.     

New approaches to investigation of bone tissue according to the isoserological system ABO

To detect ABO antigens in human bone tissue, we offer to treat standard isohemagglutinating and heteroimmune sera with anti-A and anti-B raising their specificity; use of high-avid immunoreagents produced by novel technique; different modifications of absorption-elution reactions providing significant results.     

Forensic medical significance of anti-P1 immunoreagents with incomplete antibodies in blood analysis

Anti-P1 immunoreagents with incomplete antibodies are intended for detection of antigen of different degree of manifestation in blood traces during expert evaluation of material evidences by the adsorption-elution test. These reagents can be used for detecting weakly manifest P1 antigen in liquid blood in forensic medical studies.     

Antigenic differentiation of blood stains by the Lewis system in practical forensic medical expert evaluation

A modification of quantitative absorption and absorption elution tests with blood stain washing before the absorption phase is presented. Due to washing, the effect of carrier object on anti-Le(a) and anti-Le(b) sera is decreased and the sensitivity of the method is increased. Additional adsorption of the sera and elution into test erythrocytes treated with protease C is suggested for increasing the number of standard sera fit for the absorption-elution test. A new technology for preparing anti-Le(a) and anti-Le(b) immunoreagents is described.     

弱势群体与心态失衡

弱势群体问题已成为当前困扰我国改革与发展进程的重大社会问题。弱势群体的规模不断扩大 ,社会地位呈下降态势 ,他们在生存、生计、机会和权利等方面所面临的弱势境遇 ,客观上诱发了各种消极情绪的积累。弱势群体的产生是社会矛盾的集中反映 ,也是社会缺乏公正的体现。弱势地位不仅带来了生活上的窘迫 ,更多的是心理上的失衡。而心理的失衡极大地动摇了个体原有的人生观和行为定势 ,为越轨行为的产生创造了条件。     

Ghosting phenomenon in static and dynamic footprints in India and the United States

Ghosting is the phenomenon that exists when a footprint has a lighter area around the tip of one or more toes or a shadow-like area at the back of the heel. To date, ghosting has been considered primarily a finding of dynamic (walking) footprints, rather than static (standing) footprints. The prevalence of ghosting in static footprints is unknown, and research on its presence in static and dynamic footprints from the same participant is sparse, as are studies on its occurrence in different geographic populations. This study is among the first to evaluate the occurrence of ghosting in the static and dynamic footprints from a particular individual with participants in two geographic populations.A combination of both inkless and ink footprint collection systems were used to obtain a total of 206 bare footprints from 103 adult participants from the United States and India. The data comprised 103 static and 103 dynamic footprints.Ghosting occurred significantly in static footprints, though less frequently than in dynamic footprints. Ghosting in static footprints was seen most often at the first toe, followed by the third and second respectively. This aspect appeared least at the heel. In dynamic footprints, it occurred most at the first toe, followed by the second and fourth toes, and then the third toe and the heel. The prevalence of ghosting in footprints from the United States and India differed in their locations, notably at the first and second toes in the static footprints and at the heel in the dynamic footprints.     

Marriage and power: Age at first marriage and spousal age gap in lesser developed countries

This paper examines age at first marriage for women and spousal age gap as an indicator for female agency from 1950 to 2005. Using a dataset of 77 LDCs this paper seeks to explore which variables determine differences at a country level in marriage patterns. We look at the influence of urbanisation, education, percentage population of Muslim faith, and family type. We find that education is a key in determining at what age women marry, having as would be expected a positive effect on age at first marriage and depressing spousal age gap. Urbanisation is significant, with a positive effect on age and negative on spousal age gap, although the effect is not very large. The percentage Muslim variable depresses female age at first marriage and increases spousal age gap but only when family type is not controlled for. The initially strong negative effect of percentage population Muslim over the period under consideration on age of first marriage has decreased, which raises some interesting questions about the role of Islam in female empowerment.     

Pathways to early delinquency: Exploring the individual and collective contributions of difficult temperament,low maternal involvement,and externalizing behavior

BackgroundThe purpose of this study was to investigate the impact of difficult temperament and maternal involvement, measured at ages one and three years, respectively, on externalizing behavior at age five and early delinquency at age nine.MethodsMaternal- and child-reports from 4,897 members of the Fragile Families and Child Wellbeing Study (FFCWS) were included in a path analysis of four of five waves of FFCWS data: Wave 2 (difficult temperament at age 1), Wave 3 (maternal involvement at age 3), Wave 4 (externalizing behavior at age 5), and Wave 5 (delinquency at age 9).FindingsAlthough difficult temperament at age 1 displayed a weak zero-order correlation with delinquency at age 9 and low maternal involvement at age 3 failed to correlate with delinquency at age 9, both entered into significant chained relationships with delinquency via externalizing behavior at age 5. In addition, difficult temperament at age 1 seemed to evoke low parental involvement at age 3.ConclusionsThe respective roles of a difficult temperament, maternal involvement, and externalizing behavior in a proximal chaining process may be partially responsible for the continuity that has been observed in antisocial behavior over time.     

Drug screening and confirmation by GC-MS: comparison of EMIT II and Online KIMS against 10 drugs between US and England laboratories

Drug screening through urinalysis is a widely accepted tool for rapid detection of potential drug use at a relatively low cost. It is, therefore, a potentially useful method for detecting and monitoring drug use in a variety of contexts such as the criminal justice system, pre-employment screening and a variety of treatment centers. This article explores the efficacy of two commercially available drug-screening assays: Online KIMS assay (Roche) and EMIT II assays. First, we evaluate the sensitivity and specificity of two immunoassays. A total of 738 urine samples were collected among adult arrestee populations from Chicago, New Orleans and Seattle through the Arrestee Drug Abuse Monitoring (ADAM) program. Partial samples were split within one laboratory and analyzed by both enzymes multiplied immunoassay technique (EMIT) II and kinetic interaction of microparticle in solution (KIMS) assays for a 10-drug panel (amphetamine, barbiturates, benzodiazepines, marijuana, cocaine, methadone, methaqualone, opiate, phencyclidine and propoxyphene). Gas chromatography-mass spectrometry (GC-MS) was used as a confirmation method for all positives from either EMIT II or KIMS for all experiments. Second, the paper examines whether using different testing laboratories plays a role in the final results. The same experiments were repeated at two different testing locations: one in California and one in London and England. Third, the paper studies whether drug testing results vary between two laboratories when each of them had used their own routine screening method: the Forensic Science Service (FSS) at Birmingham, United Kingdom with KIMS assay and Medscreen Limited at London, United Kingdom with EMIT II. In summary, both EMIT II and KIMS assays generate fairly consistent results. The concordance rate against each of the 10 drugs tested is relatively high (97.4-100%). The discrepancies, in most cases, occurred at drug concentrations near the cut-off levels. There were more discrepant results between two laboratories compared to when specimens were analyzed at the same laboratory using two different assays.     

Exploratory study on classification and individualisation of earprints

The FearID research project is aimed at the individualisation of earprints for the purpose of forensic research. The study presented here was carried out within the framework of this project. It intends to combine a review of what is known from literature on the classification and individualisation of earprints with results from a preliminary study of earprints. Possibilities for, and limitations to, the use of earprints in forensic investigation are addressed. Differences between eliminating a suspect, placing a suspect at a crime scene, and linking crimes by prints left at different scenes are considered.     

Sex, Property Rights, and Divorce

This paper examines how differences in sex drives between husbands and wives affect bargaining strengths during marriage and particularly at times when divorce might occur. The basic argument follows from the fact that sex drives vary over an individual's life cycle, and are systematically different for men and women. The spouse having the lowest sex drive at any time in the marriage has a property right over whether or not sexual intercourse will occur, with a consequent increase in bargaining power at the margin. The paper derives a number of testable implications from its model, and, using several data sources, shows empirically how this difference affects marriage, adultery and divorce.     

Violence, schools, and dropping out: racial and ethnic disparities in the educational consequence of student victimization

Without a doubt, exposure to violence and victimization can be profoundly detrimental to the overall well-being and development of all youth. Moreover, violence and victimization that occurs within a school context is particularly alarming because a successful educational process is essential toward establishing socioeconomic success later in life. The educational consequence of exposure to violence and victimization at school is uncertain for racial and ethnic minority students. This study utilizes data from the Education Longitudinal Study of 2002 and incorporates multilevel modeling techniques to examine the impact of violence and victimization at school on dropping out. The results indicate Black/African Americans and Latino American students who are victimized at school are at higher risk of dropping out. The implications of the evident racial and ethnic disparities in the relationship between victimization and dropping out within the U.S. school system are discussed.     

Fluorescence spectra and images of latent fingerprints excited with a tunable laser in the ultraviolet region

Fluorescence spectra of sebum-rich latent fingerprints were studied with a tunable laser for non-destructive fingerprint detection without chemical treatment. The tunable laser consists of a nanosecond pulsed Nd-YAG laser and an optical parametric oscillator (OPO) crystal. The fluorescence spectra and images were measured at various excitation wavelengths in the ultraviolet region by the time-resolved fluorescence method. We have previously reported that a typical fluorescence spectrum of fingerprints consists of two peaks located at c. 330 and 440 nm. In order to determine the wavelength of optimal excitation, excitation spectra were measured at wavelengths ranging from 220 to 310 nm. The fluorescence intensity of the 330 nm peak became maximal with excitation at 280 nm. The images of latent fingerprints on white papers were also measured and the clearest image was obtained with excitation at 280 nm. The influence of continuous irradiation on the fluorescence of fingerprints was measured at the optimal excitation wavelengths. The 330 nm peak was strong at first and decreased with continuous irradiation, whereas the 440 nm peak, which was weak at first, increased gradually.     

正常、大声两种说话状态下语音的声学差异及对声纹鉴定的影响

本文主要通过对正常、大声两种说话状态下的普通话中三个单元音[a]、[i]、[u]的声强、时长、基频、谐波振幅差值、共振峰等声学参数的分析,综合比较了各参数的变化规律,发现大声说话时的语音并非正常语音的简单放大,二者不仅在声强上存在差别,同时在频率域上也发生了重要变化。同一人不同状态下发音的频谱特征差异性较大,同种状态下发音的相似性、可比性较强,为此,声纹鉴定中应尽量选取状态相同的语音进行比对。     

Death from thermal effects and burns

One hundred and fifteen unselected autopsy cases of death from thermal effects and/or fire between 1990 and 1999 were analyzed with regard to time of death, signs of vitality at the scene of the fire, the manner and cause of death, and the extent of soft tissue loss. The cases represented approximately 6% of all autopsy cases at the Institute of Legal Medicine responsible for a catchment area with approximately 700,000 inhabitants. In 23 victims suffering burn injuries, death occurred during initial medical care or clinical treatment. The causes of death were primary respiratory arrest due to smoke poisoning or delayed shock caused by thermal injuries to the skin. Death occurred at the scene of the fatal event in 85 cases: eight cases exhibited no thermal effects; the cause of death in one of these cases was polytrauma incurred in a leap from a height; in seven cases there was poisoning due to smoke inhalation. The remaining 77 cases were characterized by signs of intensive thermal and/or fire effects. Clear signs of vitality (carboxyhemoglobin (COHb) in blood, inhalation and/or swallowing of soot) were found in 84.7% of the victims dying at the site of the fatal event. Of the 13 victims showing no signs of vitality at the scene, a cause of death could be determined in only seven cases; death in the other six cases remains unexplained. Quantification of the soft tissue loss revealed a possible correlation with the temperature and time course of heat exposure.     

The Development and Application of Random Match Probabilities to Firearm and Toolmark Identification

The field of firearms and toolmark analysis has encountered deep scrutiny of late, stemming from a handful of voices, primarily in the law and statistical communities. While strong scrutiny is a healthy and necessary part of any scientific endeavor, much of the current criticism leveled at firearm and toolmark analysis is, at best, misinformed and, at worst, punditry. One of the most persistent criticisms stems from the view that as the field lacks quantified random match probability data (or at least a firm statistical model) with which to calculate the probability of a false match, all expert testimony concerning firearm and toolmark identification or source attribution is unreliable and should be ruled inadmissible. However, this critique does not stem from the hard work of actually obtaining data and performing the scientific research required to support or reject current findings in the literature. Although there are sound reasons (described herein) why there is currently no unifying probabilistic model for the comparison of striated and impressed toolmarks as there is in the field of forensic DNA profiling, much statistical research has been, and continues to be, done to aid the criminal justice system. This research has thus far shown that error rate estimates for the field are very low, especially when compared to other forms of judicial error. The first purpose of this paper is to point out the logical fallacies in the arguments of a small group of pundits, who advocate a particular viewpoint but cloak it as fact and research. The second purpose is to give a balanced review of the literature regarding random match probability models and statistical applications that have been carried out in forensic firearm and toolmark analysis.     

Forensic dermatopathology and internal disease

The gross and microscopic analysis of skin lesions at autopsy can help the pathologist understand diseases and injuries inflicted premortem, perimortem, or postmortem. From January 2003 to January 2004, skin findings at autopsy were closely examined by a dermatologist and sampled for microscopic analysis at the Southwestern Institute of Forensic Sciences. Dermatologic abnormalities in some of these cases led to the discovery of internal disease and allowed for a more complete understanding of the pathologic disease processes affecting the individual. We present four autopsy cases with skin manifestations of internal disease, including pseudoxanthoma elasticum, calciphylaxis, the sign of Leser Trelat, and papular mucinosis, and demonstrate the usefulness of the dermatological assessment at autopsy. In all cases, discovery of these skin lesions and internal disease manifestations allowed contributing factors to the death of the individual to be uncovered.     

The Woolf report and German civil procedure

Conclusions A close look at English and German civil proceedings reveals that there are a number of common problems, but also some common solutions to these problems, despite the fact that the two legal systems have such very distinct judicial traditions. The aim of creating a judicial system which offers easy access to justice, pursuant to a procedure which is transparent and comprehensible to the population as a whole, has not yet been reached in the two countries. Lord Wolfs proposals represent an important step forward towards this common goal. The German government will be well advised to take account of the experience of the legal system of England and Wales in its future efforts to reform its own judicial system. Judge of the Landgericht, at present at the Kammergericht, Berlin.     

全球化和刑事司法

刑事司法的全球化正在逐步成为现实。而且全球化的进程旨在在世界范围内采取联合行动预防和惩治某些特定的犯罪。然而,刑事司法全球化的构建需要建立在统一的刑事司法文化基础上,与修正的报应模式和法律与秩序模式不同的是,刑事司法全球化必须有整合一致的人权文化。提高个体、政治、社会和经济人权的整体文化,是保障建立刑事司法全球化的最佳途径,它服务于国际公共价值和秩序,同时还致力于社会公正,确保相关人员,特别是被害人和被告人的权利保障。     

alpha-L-fucosidase phenotyping in human placentae, semen and seminal stains

The polymorphism of alpha-L-fucosidase (Fu) was investigated in a Japanese population from samples of placentae and semen, using isoelectric focusing. The gene frequencies of placental types were Fu1 = 0.748 and Fu2 = 0.252, and those of seminal types were Fu1 = 0.739 and Fu2 = 0.261. The coincidence in the distribution between the placental and seminal types suggests that the Fu types occurring in placentae and in semen are controlled by the same Fu alleles. The Fu typing was possible in seminal stains stored at 4 degrees C for up to 9 weeks, at room temperature for up to 7 weeks and at 37 degrees C for up to 4 weeks. The Fu types were still detectable at semen dilutions of up to 1:4. This polymorphism would provide a useful genetic marker for the medicolegal grouping of seminal stains.