Acute myoglobinuria as a fatal complication of heroin addiction

A fatal case of myoglobinuria complicating heroin addiction is described. Clinically the patient had no overt symptoms of rhabdomyolysis. Pathologists should be alerted to this rare complication in heroin addicts who die of no apparent cause. The antimyoglobin immunoperoxidase technique is useful in confirming the diagnosis.     

"三个代表"重要思想,是实现中华民族伟大复兴的行动指南

举世瞩目的党的十六大胜利闭幕了。这是一次团结的大会、胜利的大会、奋进的大会。是在我党历史上、中华民族复兴史上必将产生深远意义的一次大会。这次大会,我们党在新时期新阶段的指导思想和奋斗目标进一步确立;我们党承前启后、继往开来的新的党中央领导集体已经产生;党团结和带领全国各族人民全面建设小康社会、开创中国特色社会主义事业的历史航船已经扬帆起航。忆往昔,岁月峥嵘鼓人心;看未来,前程似锦添力量。这次大会,鼓舞人心、振奋人心、凝聚人心。江泽民同志的报告以“以高举邓小平理论伟大     

Restriction fragment length polymorphism analysis of forensic science casework in the People's Republic of China.

Restriction fragment length polymorphism (RFLP) analysis for the purpose of individualization is now being used in casework in the People's Republic of China. This report describes the use of the multilocus minisatellite probe 33.15 to solve three cases, including two homicides and a rape. In the third case, fetal tissue was analyzed to prove that the alleged rapist was, in fact, the father. In each case, analysis of deoxyribonucleic acid (DNA) resulted in a positive match. The probability of chance association of the DNA fingerprint was calculated as 5.6 x 10(-12), which is similar to the figures reported in the literature.     

法官的经验与理性

初民社会是以人神互相感应的方法来解决诉讼问题的,当今一些西方国家司法制度中仍然可以看到它的遗迹。大陆法系的司法最显著的特征是重演绎,重视法律的理论体系;而英美司法则完全是经验性的,强调遵循先例,而不注重体系。法官对法律的思辩是依赖于经验的,但是经验却不总是足以对思辩的疑惑提供裁决,所以真正的法官思辩是经验与理性的结合。法官对经验与理性的追求体现的是法律所固有的规则性及其内在的逻辑力量。理想的法官给人最深刻的印象是他们的理性,那种清晰的、冷静的经验理性。     

我国证据犯罪立法评析

证据是诉讼的灵魂,保证各种诉讼的顺利进行是刑法的内容之一.现行证据犯罪立法存在覆盖面偏窄、立法技术的严密性和系统性欠佳等弊端,不能适应诉讼程序的需要,从而影响实体法功能的实现.     

英国的调解制度--近期发展

本文分析了英国近来的一些案例,介绍了英国在采取非诉方法解决争议方面的最新发展,强调了法院在一些案件中的态度.     

东盟国家知识产权保护：立法与制度的最新发展

在过去20年中,东盟国家知识产权保护立法与制度的发展状况较少受到人们的关注。近些年来,东盟国家在知识产权保护的立法、制度创新、区域知识产权保护的统一与协调等方面都出现了新的变化,试图确立东盟在知识产权领域的主要角色地位,而避免被动地接受其他国家在知识产权保护方面所创造的原则和制定的政策,引起了世人的关注。     

Quantitative analysis of chlorpromazine by electron spin resonance (ESR) spectroscopy

A simple and sensitive method is described for quantitative analysis of chlorpromazine in blood, serum, urine and tissue homogenate. The chlorpromazine cation radical produced by adding perchloric acid and 2,3-dichloro-5,6-dicyano-p-benzoquinone to the sample can be detected by the ESR method at room temperature. The sensitivity limit is 10 ng, that is, 20 μl of the solution containing 0.5 μg chlorpromazine/ml. The time needed for the measurement is within 10 min. The chlorpromazine radical thus produced is very stable; for example, 95% of the radical was observed after 24 h. The advantage of this method is discussed by comparing with the ordinary spectrophotometry which requires the purification of the sample.     

Acidic and neutral drugs screen in blood with quantitation using microbore high-performance liquid chromatography–diode array detection and capillary gas chromatography–flame ionization detection

Blood previously acidified with aqueous saturated ammonium chloride solution was extracted with ethyl acetate. The dried extract was subjected to acetonitrile–hexane partition. The acetonitrile portion was analysed for the presence of acidic and neutral drugs by HPLC–DAD (200 mm×2.1 mm I.D. microbore ODS-Hypersil column) and GC–FID (25 m narrow-bore×0.25 mm I.D. HP-5 column with 0.33 μm film thickness). The protocol was found to be suitable for both clinical toxicology (including emergency toxicology) and postmortem toxicology. At least 66 drugs of interest were unequivocally identified by RRTs (HPLC) and UV spectra (DAD) match while another 12 were unequivocally identified by double RRTs match (HPLC and GC). Quantitation was facilitated by incorporating calibration blood standards in each assay batch. The five drugs most commonly encountered in clinical blood specimens (1150 cases) were: paracetamol (47.4% of the cases); chlormezanone (6.6%), theophylline (1.74%), naproxen (1.65%) and mefenamic acid (1.56%). The following drugs were detected in toxicologically significant quantities in postmortem blood specimens (245 cases): phenobarbitone (1.22% of the cases), naproxen (0.82%), chlormezanone (0.82%), theophylline (0.82%), carbamazepine (0.41%) and paracetamol (0.41%).