Das "9+1"-Modell der Verwaltungsgerichtsbarkeit

Ohne Zusammenfassung     

Usefulness of combining clinical and radiological dental findings for a more accurate noninvasive age estimation

The aim of this study was to establish correlations of clinical and radiological dental findings, alone or in combination, with chronological age in adults. Dental findings and orthopantomograms of 984 patients (aged 20-60 years; 524 females/460 males) were analyzed. DMF-T index and distance (alveolar bone level, ABL) between cemento-enamel junction and alveolar bone margin were recorded. Additionally, clinical and radiological findings at each tooth crown and root were collected according to the actual status of destruction and restoration, and a total score for each dentition (TSD) was calculated. After univariate correlation analysis, correlation coefficients for ABL and TSD were improved by using square root (sqrt). However, the determination accuracy was still not satisfactory; 90% of the residuals were in the range of about +/-10. The present study showed that clinical and radiological dental findings could not be used, not even in combination, for accurate age estimation as a single method, but that they could support other methods.     

Parteien und die Generosität der Altersrenten in Zeiten permanenter Austerität

Zusammenfassung: Die quantitative Sozialpolitikforschung weist ein doppeltes Defizit auf: Zum einen dominieren Analysen aggregierter Ausgaben(quoten), zum anderen fokussieren die meisten Studien zu Lohnersatzraten auf die Arbeitslosen‐ und Krankenversicherung, während die Rentengenerosität weitgehend ausgespart geblieben ist. Der vorliegende Artikel stößt in diese Lücke, indem er zunächst die theoretischen Besonderheiten der Rente diskutiert und zwei Hypothesen zu deren Rückbau und der Rolle der Parteien dabei formuliert. Im Anschluss an eine Methodendiskussion präsentieren wir die Ergebnisse von (robustheitsgetesteten) Regressionsanalysen der Veränderungen der Lohnersatzraten in 18 entwickelten Demokratien. Es zeigt sich, dass die Kürzungen der Lohnersatzraten im Rentenbereich weitaus geringer ausfallen als in den beiden anderen Bereichen, und dass sich die Parteieneffekte auffallend unterscheiden.     

Rechtzeitigkeit von falsch adressierten Eingaben im WebERV

Die Funktion der Bundesrechenzentrum GmbH als "vorgelagerte Einlaufstelle des Gerichts" ?ndert nichts daran, dass ein im Wege des ERV übermitteltes Schriftstück – unter Nichteinrechnung des Postenlaufs – nur dann als rechtzeitig eingebracht angesehen werden kann, wenn es durch Angabe des jeweils zutreffenden "Dienststellenkürzels" an das richtige Gericht adressiert war. Langte der Schriftsatz wegen unrichtiger Bezeichnung des Adressatgerichts beim falschen Gericht ein, das ihn (mit Zeitverz?gerung) an das zust?ndige Gericht übermitteln musste, so ist die Eingabe nur dann als rechtzeitig anzusehen, wenn sie noch innerhalb der Rechtsmittelfrist beim zust?ndigen Gericht einlangt. Für die Beurteilung der Fristwahrung von im ERV eingebrachten Rechtsmitteln kommt dem Vorhandensein vereinigter Einlaufstellen iSd § 37 Abs 2 Geo keine Relevanz zu. Auch in diesem Fall schlie?t die unrichtige Bezeichnung des Adressatgerichts die Anwendung des § 89 GOG zu Lasten des Rechtsmittelwerbers aus.     

Anabolic androgenic steroids in police cases in Sweden 1999-2009

Anabolic Androgenic Steroids (AAS) are considered drugs of abuse and are controlled substances in Sweden since 1999. Traditionally AAS have been used by elite athletes to enhance performance, but in recent years it has become an increasing problem outside elite sport among athletes, bodybuilders and criminals. Use of AAS is associated with psychiatric side effects such as aggression, depression and violent behavior. Supraphysiological doses and long term use can cause serious physical harm such as cardiovascular toxicity and even premature death. We investigated and evaluated the drug analytical findings in forensic cases from suspected perpetrators in cases from the police where a screening for AAS was requested to get information about the prevalence of AAS use and the occurrence of poly-drug abuse. The study was based on samples submitted from the police authorities to the Department of Forensic Toxicology in Sweden during the period 1999-2009. Urines were analyzed by methods based on GC-MS and LC-MS-MS. We also analyzed the prevalence of AAS use at the prison and probation services. A total number of 12,141 urine samples (6362 police cases and 5779 inmates) were analyzed and 33.5% of the cases from the police and 11.5% of the inmates were tested positive for AAS. The users of AAS were mainly in 99.2% men with a mean age of 26.2±6.2 years whereas the women were 29.5±6.5 years old. The most frequently used AAS was nandrolone followed by testosterone and methandienone. Other illicit and licit drugs were detected in 60% of the cases from the police, strongly indicating a frequent poly-drug abuse among users of AAS.     

Investigation of morphine and morphine glucuronide levels and cytochrome P450 isoenzyme 2D6 genotype in codeine-related deaths

Compared to morphine and morphine-6-glucuronide (M6G), codeine and its other major metabolites codeine-6-glucuronide and norcodeine have weak affinity to opioid μ-receptors. Analgesic effects of codeine are thus largely dependent on metabolic conversion to morphine by the polymorphic cytochrome P450 isoenzyme 2D6 (CYP2D6). How this relates to toxicity and post-mortem whole blood levels is not known. This paper presents a case series of codeine-related deaths where concentrations of morphine, M6G and morphine-3-glucuronide (M3G), as well as CYP2D6 genotype, are taken into account. Post-mortem toxicological specimens from a total of 1444 consecutive forensic autopsy cases in Central Norway were analyzed. Among these, 111 cases with detectable amounts of codeine in femoral blood were identified, of which 34 had femoral blood concentrations exceeding the TIAFT toxicity threshold of 0.3mg/L. Autopsy records of these 34 cases were retrieved and reviewed. In the 34 reviewed cases, there was a large variability in individual morphine to codeine concentration ratios (M/C ratios), and morphine levels could not be predicted from codeine concentrations, even when CYP2D6 genotype was known. 13 cases had codeine concentrations exceeding the TIAFT threshold for possibly lethal serum concentrations (1.6 mg/L). Among these, 8 individuals had morphine concentrations below the toxic threshold according to TIAFT (0.15 mg/L). In one case, morphine as well as M6G and M3G concentrations were below the limit of detection. A comprehensive investigation of codeine-related fatalities should, in addition to a detailed case history, include quantification of morphine and morphine metabolites. CYP2D6 genotyping may be of interest in cases with unexpectedly high or low M/C ratios.     

Ethyl glucuronide in human hair after daily consumption of 16 or 32 g of ethanol for 3 months

The overall objectives of the study were to develop a sensitive method for ethyl glucuronide (EtG) determination in hair and then investigate if a low or moderate intake of ethanol could be differentiated from total abstinence. Forty-four subjects were included in the study, 12 males (7 drinkers and 5 abstinent) and 32 females (14 drinkers and 18 abstinent). The study lasted 3 months and the female drinkers consumed one glass (16 g of ethanol) and the males consumed two glasses (32 g of ethanol) of wine (13.5-14%) daily. Hair samples were collected as close as possible above the skin and the proximal 2 cm were analyzed for EtG. Hair was cut into pieces of about 0.5 cm length and washed before incubation overnight in water and then extracted on Clean Screen EtG Carbon columns. The LC/MS/MS system consisted of a Waters ACQUITY UPLC connected to an API 4000 triple quadrupole instrument. Two transitions for EtG and one for the internal standard EtG-D(5) were measured. The method was linear from 60 to 10,000 pg/sample. Imprecision studies were performed at three levels as well as with an authentic sample. Total imprecision was 16% at 200 pg/sample, 8% at 1000 pg/sample, 6% at 8000 pg/sample and 13% at 29 pg/mg in the authentic sample. Of those who drank two glasses of wine every day, four had measurable amounts of EtG in their hair (5-11 pg/mg), and in only one of the females drinking one glass of wine EtG was quantified (3 pg/mg). Among the 23 abstinent subjects two had traces of EtG in the hair. We conclude that persons who ingested 16 or 32 g of ethanol daily for 3 months presented with low concentrations of EtG in hair, well below the proposed threshold for overconsumption set at 30 pg/mg. In addition, none of those who ingested 16 g/day had concentrations over the proposed abstinence threshold of 7 pg/mg.