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Prolapse rectum (PR) or protrusion of the rectum beyond the anus occurs frequently in populations at both extremes of age. In the pediatric population, in developed countries, the commonest cause for PR is thought to be cystic fibrosis (CF). Treatment options for CF include conservative management, surgical resection and fixation, suturing, and injection sclerotherapy (IS). The last is considered an attractive treatment option because it is minimally invasive. In this case report, the authors present the details about a 2-year-old female child, with PR and CF, who died after IS, using phenol as the sclerotherapeutic agent. Autopsy findings and toxicology tests performed to establish phenol toxicity are documented. The available literature is reviewed. This case report underscores the risks of using phenol for IS and emphasizes the point that the procedure is not innocuous and an adverse outcome including fatality is a possibility. 相似文献
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Publically accessible, illegal, websites represent an additional challenge for control agencies, but also an opportunity for researchers to monitor, in real time, changes in criminal careers. Using a repeated measures design, we examine evolution in the networks that form around child exploitation (CE) websites, over a period of 60 weeks, and determine which criminal career dimensions predict website failure. Network data were collected using a custom-designed web-crawler. Baseline survival rates were compared to networks surrounding (legal) sexuality and sports websites. Websites containing CE material were no more likely to fail than comparisons. Cox regression analyses suggest that increased volumes of CE code words and images are associated with premature failure. Websites that are more popular have higher odds of survival. We show that traditional criminal career dimensions can be transferred to the context of online CE and constitute some of the key determinants of an interrupted career. 相似文献
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Abstract. Drawing on the political theories of corporatism, neo–liberalism and pluralism, and on comparative empirical research in Brussels, Germany, Sweden and the UK, this article conceptualises the nature of Europeanised medicines regulation. It argues that a marketisation of regulation has been established in the European Union as a result of competition between national regulatory agencies for 'regulatory business' from the pharmaceutical industry. In the pharmaceuticals sector the Europeanised regulatory state is a product of three key factors: (a) the European Commission's commitment to an 'efficiency' regime which would meet the political objectives of a single European market and the commercial agendas of transnational pharmaceutical companies, (b) the endemic corporate bias associated with medicines regulation in the most influential member states, and (c) the considerable success of neo–liberal politics across a number of major member states, including Germany, Sweden and the United Kingdom. 相似文献
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Abraham?CarmeliEmail author Leanne?Atwater Avi?Levi 《The Journal of Technology Transfer》2011,36(3):257-274
Knowledge exchange among employees is crucial to organizational effectiveness. Leadership can enhance or detract from employees’
willingness to share knowledge. This study examines how leadership affects knowledge sharing in a knowledge-intensive work
setting. It proposes and tests a model which posits that (1) transformational leadership affects the extent to which employees
identify with their manager; (2) this relational identification, mediated by the quality of LMX (Leader-Member Exchange),
leads to greater identification with the organization and its goals, which in turn results in greater knowledge sharing. The
sample consisted of two hundred and three R&D employees engaged in advanced technological projects. Path analysis results
indicated that there are both direct and indirect (through LMX) relationships between transformational leadership and relational
identification: relational identification promotes organizational identification which, in turn, is positively related to
knowledge sharing. These results highlight the importance of transformational leadership and LMX for promoting relational
and organizational identification, thereby facilitating employee knowledge sharing. 相似文献
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The behavioral work context in which members of groups interact with each other is crucial for facilitating knowledge exchange and combination (Nonaka in Great minds in management: the process of theory development, Oxford University Press, Oxford 2005; Nonaka et al. in Long Range Plan 33:5–34, 2000). Yet little is known about the ways leaders, by signaling expectations and exhibiting supportive behaviors, facilitate such a behavioral context, which may then enhance performance. This study aims to contribute to the literature by examining how leader expectations and supportive behaviors facilitate behavioral integration and enhance the performance of work groups engaging in the development of advanced technological products. Data collected from management teams of 102 work groups indicate significant and positive relationships between: (1) leader expectations and leader supportive behaviors, (2) leader supportive behaviors and group behavioral integration, and (3) behavioral integration and group performance. In addition, the results indicate that leader supportive behaviors partially mediate the relationship between leader expectations and group behavioral integration, and the latter partially mediates the link between leader supportive behaviors and group performance. No significant link was found between leader expectations and group performance. In so doing, this study contributes to research on the way leaders, by shaping a behavioral context, facilitate knowledge exchange and combination, thereby enhancing group performance. 相似文献
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Herbert S. Levine Abraham S. Becker Abram Bergson Andrew R. Bond Padma Desai Ed A. Hewett 《后苏联事务》2013,29(1):40-53
The proceedings of a panel of American specialists devoted to the recent economic reform are summarized. The panelists noted that the most substantial changes to date have accompanied efforts to restructure the decisionmaking hierarchy—in particular, a recentralization of authority through the creation of biuros and state committees and legislation on individual economic activity. Changes in the systems of economic planning and incentives, on the other hand, have been minor, suggesting a continuing debate over the extent to which price reform and various economic incentives should be implemented. Journal of Economic Literature, Classification Numbers: 052, 113, 124. 相似文献