Detection of ABH blood group antigens in the saliva of Koreans and their stability according to storage of saliva samples

The purpose of the present study was to identify salivary molecules carrying the ABH blood group antigens in Koreans and to investigate the changes in these antigens according to processing and storage of saliva samples. Secretor or non-secretor phenotypes and salivary components carrying the ABH antigens were identified in 90 subjects, 30 subjects in each ABO blood group, by SDS-PAGE and immunoblotting. Saliva samples were then obtained from 12 secretors-two males and two females in each ABO blood group and aliquots of both fresh saliva samples and their supernatants after centrifugation were stored at room temperature, 4, -20 and -70 degrees C. The same experiments were performed after 1, 3 and 6 months to investigate changes in the blood group antigens. In all 68 secretors, high-molecular-weight salivary mucin (MG1) was found to be the primary carrier of the ABH antigens. A salivary component of approximately 80 kDa also carried H antigen in seven saliva samples of 22 blood type O secretors. The blood group antigens were better detected in centrifuged samples. In saliva samples preserved at room temperature and 4 degrees C, the blood group antigens were either not detected or detected as degraded molecules. No change was found in the blood group antigens in saliva samples preserved at -20 and -70 degrees C for 6 months.     

National-Level Family Policies and workers’ Access to Schedule Control in a European Comparative Perspective: Crowding Out or In,and for Whom?

Abstract

This paper examines national-level family policies in a comparative perspective, to see whether they “crowd out” company-level family-friendly policies, namely schedule control. Further, it examines whether this relationship varies for different types of family policies, and for different groups of workers – i.e. distinguished by gender, parenthood status and skill divisions. The paper uses data from 27 European countries in 2010, and applies multilevel random slopes models with cross-level interaction terms. Results show that generous national-level family policies, in particular work-facilitating policies, “crowd in” company-level schedule control provisions, especially for high-skilled workers. However, very generous leave entitlements seem to crowd out schedule control provision.     

China-Japan Relations in the Post-Koizumi Era: a Brightening Half-decade?

The tenure of Japanese Prime Minister Junichiro Koizumi (2001–2006) was vexing for China-Japan relations. As such, the five years since Koizumi left office, particularly the change in Japan's ruling party, were initially expected, and sometimes perceived, to realize a half-decade of recovery and reconciliation in Sino-Japanese ties. While tensions did decrease, “icebergs” blocking improvement in relations have not completely thawed, and may harden again. Competition for political and economic influences and interests in the same region, concern over one another's future security posture and relations with Taiwan, territorial disputes, misunderstanding about the other's historical sensitivities and feelings of distrust, occasionally manipulated by nationalists, still pervade the relationship. Therefore, though there is mutual desire, indeed a necessity, for cooperation on many issues affecting both countries, this typically couples with a disconcerting or anxious feeling towards the other's intentions that results in competitiveness. There are deep roots to this need/fear complex.     

What is wrong with job security?

Most Western studies into motivation suggest that public servants are prosocial. Moreover, scholars suggest that a desire for external rewards, like pay and job security, may crowd out prosocial proclivity. However, recent studies from non‐Western contexts provide mixed results about the actual drivers of public servants' motivation to seek and retain public sector employment and perform their duties. To advance the development of theory regarding motivational dynamics of public servants in developing countries, we examine how pursuing external rewards impacts public service motivation, job satisfaction, and turnover intention among public servants in Kazakhstan (n = 627), a developing former Soviet republic that has been subjected to various waves of personnel reform. Our quantitative and qualitative data show that a desire for job security relates positively to public service motivation and job satisfaction, whereas a desire for monetary rewards correlates negatively with public service motivation and positively with turnover intention. We conclude with the implications for theory and practice.     

Detection of phentermine in hair samples from drug suspects

Phentermine (PT) has been widely used as an anti-obesity drug. This drug has to be used with caution due to its close resemblance with amphetamines in its structure and toxicity profile. Recently, PT is in distribution by illegal modes and is found to be available through sources such as the internet, thus their misuse and/or abuse is threatening to be a serious social issue. In the present study, 32 cases of drug suspects were observed for PT abuse, detected using hair samples for drug analysis. PT and other amphetamines, such as methamphetamine (MA), amphetamine (AP), 3,4-methylenedioxyamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA), were extracted using 1% HCl in methanol for 20 h at 38°C. The extracts were derivatized with trifluoroacetic anhydride (TFAA) and analyzed using gas chromatography/mass spectrometry (GC/MS). Among the 32 cases of PT abuse, MA and its main metabolite, AP were identified in seven cases and MDMA and its main metabolite, MDA were detected in two other cases.     

Pushing the Envelope for Representation and Participation: the case of homeowner activism in Beijing

This article discusses the evolution of urban homeowner activism in two senses: internally (growth through internal diversity) and externally (advancement in interaction with the state). The combination of these two aspects has directed the activism toward the expansion of its boundaries, as well as advanced representation and participation. Based on cumulative fieldwork carried out since 2007, I discuss two homeowner organizations in Beijing as core cases. Rights activism by homeowners has grown beyond the state-set boundaries of individual neighborhoods and has begun deploying innovative strategies and adapting existing institutions for its own use. Rights awareness and manifestation by social actors has evolved continuously. This evolution suggests the emergence of a complex interplay between state and society which goes beyond a confrontational or lopsided relationship.     

On statistical analysis of forensic DNA: theory, methods and computer programs

Statistics plays an important role in evaluating the evidential weight of forensic DNA. In this paper, general statistical principles for forensic DNA analysis are presented. We introduce the theory and methods for the statistical assessment in kinship determination and DNA mixture evaluation. In particular, analytical formulas for testing for biological relationship among three individuals and for assessing the DNA mixture evidence in the case of multiple subdivided ethnic groups are developed. Two user-friendly computer programs are demonstrated to exhibit their wide applicability in tackling with complex kinship/paternity and mixture problems. The EasyDNA program can solve a complicated paternity case in 1 min.     

Simultaneous analysis of d-3-methoxy-17-methylmorphinan and l-3-methoxy-17-methylmorphinan by high pressure liquid chromatography equipped with PDA

d-3-Methoxy-17-methylmorphinan (Dextromethorphan, DXM), which is a structural analog of morphine and codeine, has been widely used as a non-narcotic antitussive agent. It is a safe drug in therapeutic dose and does not produce analgesic effects, while its enantiomer, l-3-methoxy-17-methylmorphinan called levomethorphan (LXM) is a potent narcotic analgesic. DXM has been widely abused in Korea due to its hallucinogenic effect in large doses; therefore, the health authorities have regulated its use as a psychotropic agent since 2003. As its abuse has been serious, a possibility that DXM would be smuggled into Korea has also increased. Moreover, it has been suspected that there was the possibility of the adulteration or substitution of DXM with LXM due to their chemical similarities. Therefore, it was necessary for us to establish the enantiomeric separation of DXM and LXM. In this study, a liquid chromatographic method using a chiral column capable of separating stereoisomers of DXM as well as analyzing the major metabolites of DXM, 3-methoxymorphinan, 3-hydroxymorphinan, and 17-hydroxymethylmorphinan was developed. The validation of a method was studied through repeatability of retention times. Using this method, 32 confiscated DXM samples were analyzed to identify the enantiomers of DXM. As a result, DXM was detected in all samples and there was no evidence of the adulteration or substitution of DXM with LXM. Nevertheless, the stereochemical analysis of DXM and LXM is important not only to identify starting materials for illegal drug manufacture but also to understand the trends of abused drugs.     

Problems and profitability of direct foreign investiment in China: An analysis of the survey data

By analyzing a survey in the Tianjin area, this article investigates the problems and profitability of joint ventures in China, and draws some policy implications. The authors find that there are a number of systemic constraints on the profitability of joint ventures, such as input and foreign exchange shortages, rigid labor policies, conflicts between business partners, and uneasy relations with state authorities. The article concludes that unless the investment environment is improved, China will not succeed in the competition with other developing countries in attracting the foreign capital needed for its modernization. Chung H. Lee is a professor of economics at the University of Hawaii at Manoa and research associate at the Institute for Economic Development and Policy of the East-West Center. He is also author ofThe Economic Development in Japan and Korea (Praeger 1990) andTrade and Investment in Services (Westview 1988).