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151.
152.
Kranioti EF Mavroforou A Mylonakis P Michalodimitrakis M 《Forensic science international》2007,167(1):56-58
The death of a female anaesthesiologist is reported. Although the situation at the scene indicated propofol overdose-related death, self-administration of such high doses of propofol was unlikely, given the pharmacological properties of this drug. The analysis of the situation at the scene and the toxicological analysis in which the blood and liver propofol concentrations were 2.40microg/ml and 0.56microg/g, respectively, supported the conclusion that the death was a consequence of propofol self-administration at therapeutic doses from a person who used the drug on chronic basis seeking to its euphoric effects. However, because the toxic concentrations of propofol in non-intubated patients may be different from those intubated and fully supported in the operating room or in the intensive care unit, a mere interpretation of the blood and tissue concentrations of propofol in the toxicological analysis can confirm the drug intake but it may be of limited diagnostic significance without taking into account this difference. 相似文献
153.
Caramelli D Lalueza-Fox C Capelli C Lari M Sampietro ML Gigli E Milani L Pilli E Guimaraes S Chiarelli B Marin VT Casoli A Stanyon R Bertranpetit J Barbujani G 《Forensic science international》2007,173(1):36-40
We report on the mitochondrial DNA (mtDNA) analysis of the supposed remains of Francesco Petrarca exhumed in November 2003, from the S. Maria Assunta church, in Arquà Padua (Italy) where he died in 1374. The optimal preservation of the remains allowed the retrieval of sufficient mtDNA for genetic analysis. DNA was extracted from a rib and a tooth and mtDNA sequences were determined in multiple clones using the strictest criteria currently available for validation of ancient DNA sequences, including independent replication. MtDNA sequences from the tooth and rib were not identical, suggesting that they belonged to different individuals. Indeed, molecular gender determination showed that the postcranial remains belonged to a male while the skull belonged to a female. Historical records indicated that the remains were violated in 1630, possibly by thieves. These results are consistent with morphological investigations and confirm the importance of integrating molecular and morphological approaches in investigating historical remains. 相似文献
154.
155.
Ascension Barajas Elena Huergo Lourdes Moreno 《The Journal of Technology Transfer》2012,37(6):917-942
The objective of this paper is to analyse the effects of international R&D cooperation on firms?? economic performance. Our approach, based on a complete data set with information about Spanish participants in research joint ventures supported by the EU Framework Programme during the period 1995?C2005, establishes a recursive model structure to capture the relationship between R&D cooperation, knowledge generation and economic results, which are measured by labour productivity. In the analysis we take into account that the participation in this specific type of cooperative projects implies a selection process that includes both the self-selection by participants to join the consortia and the selection of projects by the European Commission to award the public aid. Empirical analysis has confirmed that: (1) R&D cooperation has a positive impact on the technological capacity of firms, captured through intangible fixed assets and (2) the technological capacity of firms is positively related to their productivity. 相似文献
156.
Elena Crinela Holom Oana Sorescu-Iudean Mihaela Hărăguș 《The History of the Family》2018,23(2):329-358
The present study focused on age at first marriage in Transylvania between 1850 and 1914, a time of both social-economic change and resilient historically entrenched particularities. Based on data extracted from the Historical Population Database of Transylvania we constructed an extensive sample from settlements with a broad range of social-economic characteristics, which allowed for a comparative view into the influence of various factors on marriage timing. We examined in this sense both individual-level co-variates, such as denominational affiliation, migration background, and social-occupational status, as well as broader factors, such as the development level attained by certain settlements and the time frame. We found that the area level of development measured according to a heuristic index was in many cases more decisive than individual characteristics in shaping individuals’ constraints and opportunities on the marriage market. More significantly, the analysis showed that the ways in which the development level worked to transform marriage timing for both men and women could be explained by historically entrenched differences and specificities. At the same time, these patterns in age at first marriage, given by factors such as denomination, might be the result of other largely still invisible factors, for which the variables used are merely imperfect proxies. 相似文献
157.
The Y-chromosomal binary marker P25 is a paralogous sequence variant, rather than a SNP: three copies of the P25 sequence lie within the giant palindromic repeats on Yq, and one copy has undergone a C to A transversion to define haplogroup R1b (designated C/C/A). Since gene conversion is known to be active in the palindromic repeats, we reasoned that P25 might be liable to back-mutation by gene conversion, yielding the ancestral state C/C/C. Through analysis of a set of binary markers in Y-chromosomes in two large samples from Great Britain and the Iberian Peninsula we show that such conversion events have occurred at least twice, and provide preliminary evidence that the reverse conversion event (yielding C/A/A) has also occurred. Because of its inherent instability, we suggest that P25 be used with caution in forensic studies, and perhaps replaced with the more reliable binary marker M269. 相似文献
158.
This article examines the complexities of women’s increasing participation in international development programming for gender equality. Taking a specific setting in rural Kyrgyzstan where one such project has been operating, the researchers discover adverse effects on the local women’s livelihoods, status and health. Women’s contradictions are attributed to the women’s own failures and lacks, creating confusion and frustration among them. Adopting Smith’s institutional-ethnography approach, we explicate and map out the hidden processes which must be held accountable for these reactionary outcomes, taking women’s experiences as entry points to inquiry. We find that the reactionary effects are not accidental but organized, powerfully, systematically but invisibly, by taken-for-granted institutional practices serving the purposes of global development institutions, where women are seen as instruments of global economic growth. The analysis provokes critical discussion of ‘how’ and ‘what’ it takes to transform Central Asian women into ‘empowered’ people. 相似文献
159.
What is the relationship between natural disasters and country size? Is an increasing likelihood of environmental shocks linked to political integration or secessionism? We argue that natural disasters are associated with a decline in country size. This relationship arises because costs generated by disasters are higher for citizens located farther away from the political center of a country, and costs are amplified as disasters affect a larger area in a country, which in turn makes it less desirable for citizens in remote regions to remain part of a larger country. Our empirical results show that greater risks of environmental shocks are indeed associated with smaller countries, as well as smaller administrative units. 相似文献
160.
The Effect of Temperature and Laboratory Rearing Conditions on the Development of Dermestes maculatus (Coleoptera: Dermestidae) 下载免费PDF全文
Noelia I. Zanetti Ph.D. Elena C. Visciarelli Ph.D. Néstor D. Centeno Ph.D. 《Journal of forensic sciences》2016,61(2):375-381
Experiments were conducted to study the life cycle of Dermestes maculatus and to establish the total developmental time and the developmental time of immature stages, in relation with six different temperatures. We also analyzed the variations in size, morphology, and other indicators of temporal variation during life cycle of D. maculatus, in relation with temperature. One hundred larvae were selected per experiment, reared individually. The remaining larvae were reared to evaluate and establish temporal variations among the instars (length, cephalic width, and dry weight). In all trials, survivorship was greater than 50% and seven larval instars were found. Data of the average developmental time of immature stages and of the total cycle, at different temperatures, are provided. This is of relevance when estimating particularly, a minimum PMI. No relation between morphometric parameters and temperature was found, suggesting that other random factors may have been involved. Thus, this indicates that the method of isomegalen diagrams could not be used for calculating PMI. 相似文献