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排序方式: 共有1006条查询结果,搜索用时 15 毫秒
21.
High‐throughput sequencing (HTS) of large panels of single nucleotide polymorphisms (SNPs) provides an alternative or complimentary approach to short tandem repeats (STRs) panels for the analysis of complex DNA mixture forensic samples. For STRs, methods to estimate individual contribution concentrations compare capillary electrophoresis peak heights, peak areas, or HTS allele read counts within a mixture. This article introduces three approaches (mean, median, and slope methods) for estimating individual DNA contributions to forensic mixtures for HTS/massively parallel sequencing (MPS) SNP panels. For SNPs, the major:minor allele ratios or counts, unique to each contributor, were compared to estimate contributor proportion within the mixture using the mean, median, and slope intercept for these alleles. The estimates for these three methods were typically within 5% of planned experimental contributions for defined mixtures.  相似文献   
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The debate over electoral reform has largely focused on representation in Parliament. However, the government largely controls policy‐making in parliamentary systems like Canada. This article shows that a more proportional system would increase the likelihood of coalitions. Because the dominant approach to studying representation in government, ideological congruence, suggests that reforming the electoral system would make no change to the level of representation, this article focuses instead on the representation of party preferences. It shows that multi‐party cabinets, common under proportional systems, involve a trade‐off between including more citizens’ preferred parties in government, while reducing the overall level of party preference representation.  相似文献   
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Social Justice Research - Acting on one’s moral principles is not always easy. Upholding one’s moral beliefs may run counter to one’s social environment or situational demands. It...  相似文献   
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Rethinking Timing of First Sex and Delinquency   总被引:1,自引:1,他引:0  
The relation between timing of first sex and later delinquency was examined using a genetically informed sample of 534 same-sex twin pairs from the National Longitudinal Study of Adolescent Health, who were assessed at three time points over a 7-year interval. Genetic and environmental differences between families were found to account for the association between earlier age at first sex and increases in delinquency. After controlling for these genetic and environmental confounds using a quasi-experimental design, earlier age at first sex predicted lower levels of delinquency in early adulthood. The current study is contrasted with previous research with non-genetically informative samples, including Armour and Haynie (2007, Journal of Youth and Adolescence, 36, 141–152). Results suggest a more nuanced perspective on the meaning and consequences of adolescent sexuality than is commonly put forth in the literature.
K. Paige HardenEmail:

Kathryn Paige Harden, M.A.   received a B.S. in Psychology from Furman University and is currently a doctoral candidate in Clinical Psychology at the University of Virginia. Her research interests include behavior genetic methodology, as well as the development of child and adolescent externalizing psychopathology. Jane Mendle, M.A.   received a B.A. in Psychology from Amherst College and is currently a doctoral candidate in Clinical Psychology at the University of Virginia. Her research interests include the antecedents of pubertal and sexual development, and the consequences of early puberty for psychological adjustment. She is currently a predoctoral intern at New York Presbyterian Hospital in Manhattan. Jennifer E. Hill, M.A.   received a B.A. in Psychology from Dartmouth University and is currently a graduate student in Clinical Psychology at the University of Virginia. Her research interests include the role of peer relationships in the development of adolescent alcohol use and delinquent behavior. Eric Turkheimer, Ph.D.   received a Ph.D. in Clinical Psychology from the University of Texas. He is a Professor of Psychology and the Director of Clinical Training at the University of Virginia. His research focuses on quantitative issues in behavior genetics, gene–environment interaction in the development of intelligence, and measurement of personality and personality disorders. Robert E. Emery, Ph.D.   received a Ph.D. in Clinical Psychology from the State University of New York at Stony Brook. He is a Professor of Psychology and the Director of the Center for Children, Families, and the Law at University of Virginia. His research focuses on family relationships and children’s mental health, including parental conflict, divorce, child custody, and associated legal and policy issues.  相似文献   
26.
Visas and work permits: Possible global negotiating initiatives   总被引:1,自引:0,他引:1  
We discuss global options for initiatives intended to ameliorate adverse impacts of visa and work permit systems used by national governments around the world. We first describe and document some of their effects, noting the relative lack of other research work on these issues. We then discuss proposals for a new and supplemental global visa structure which have been made as part of the Mode 4 GATS negotiations in the WTO, suggesting that the GATS/WTO may be an imperfect institutional location for negotiating on these matters. We then evaluate other approaches, including what realistically could be possible if a new body specifically created for global negotiation in the area were to be used.
John WhalleyEmail:
  相似文献   
27.
Local government managers are described as key participants in the development of interlocal cooperation, but the interests of city councils in this process have gone largely unstudied. Here, the author addresses the theoretical importance of council-manager relations in interlocal public service cooperation. Three propositions identify areas of shared council-manager responsibility. Evidence from in-depth interviews with city council members is used to assess each proposition. While interlocal partnership has been described as a managerial activity, council members take an interest in network development and agreement assessment. Managers, on the other hand, give greater attention to public participation and education. The evidence refines assumptions about council-manager roles in the formation of cooperative agreements, with important implications for local government management.  相似文献   
28.
Eric Helland  Yaron Raviv 《Public Choice》2008,134(3-4):255-262
The existing literature does not agree on the optimal jury size. We demonstrate that the probability of type I and type II errors is not sensitive to the number of jurors under the following three conditions: jurors receive independent signals about a defendant’s guilt during the evidence stage of the trial; the jurors truthfully reveal their signals before deliberations begin through their votes on the first ballot; and the jury’s deliberation follows a random walk. Since the opportunity cost of jury service is positive, this implies an optimal jury size of one.  相似文献   
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