Drug Recognition Evaluation and Chemical Confirmation of a 25C‐NBOMe‐Impaired Driver

This case report details an individual arrested for drug‐impaired driving after leaving the scene of multiple motor vehicle collisions and evading police. The driver was examined by a drug recognition expert and failed the drug recognition evaluation. The driver admitted to using cocaine, marijuana, an antidepressant medication and “N‐bomb,” a novel psychoactive substance that possesses hallucinogenic properties. Toxicological analyses at the Centre of Forensic Sciences’ Toronto laboratory revealed only the substance 2‐[4‐chloro‐2,5‐dimethoxyphenyl]‐N‐[(2‐methoxyphenyl)methyl]ethanamine (25C‐NBOMe) in the accused's urine. This is the first report in which 25C‐NBOMe was identified through DRE and toxicological analyses in a drug‐impaired driver.     

Using Cluster Analysis and ICP‐MS to Identify Groups of Ecstasy Tablets in Sao Paulo State,Brazil

The variations found in the elemental composition in ecstasy samples result in spectral profiles with useful information for data analysis, and cluster analysis of these profiles can help uncover different categories of the drug. We provide a cluster analysis of ecstasy tablets based on their elemental composition. Twenty‐five elements were determined by ICP‐MS in tablets apprehended by Sao Paulo's State Police, Brazil. We employ the K‐means clustering algorithm along with C4.5 decision tree to help us interpret the clustering results. We found a better number of two clusters within the data, which can refer to the approximated number of sources of the drug which supply the cities of seizures. The C4.5 model was capable of differentiating the ecstasy samples from the two clusters with high prediction accuracy using the leave‐one‐out cross‐validation. The model used only Nd, Ni, and Pb concentration values in the classification of the samples.     

Origin,Analytical Characterization,and Use of Human Odor in Forensics

Developing a strategy to characterize the odor prints of individuals should be relevant to support identification obtained using dogs in courts of justice. This article proposes an overview of the techniques used for the forensic profiling of human odor. After reviewing the origin of human odor—both genetic and physiological—the different analytical steps from sample collection to statistical data processing are presented. The first challenge is the collection of odor, whether by direct sampling with polymer patches, cotton gauze, etc., or indirect sampling with devices like Scent Transfer Unit. Then, analytical techniques are presented. Analyses are commonly performed with gas chromatography coupled with mass spectrometry. As they yield large amounts of data, advanced statistical tools are needed to provide efficient and reliable data processing, which is essential to give more probative value to information.     

A Brief History of Arts Marketing Thought in North America

Marketing is a relatively new academic discipline. Arts marketing as a subfield of marketing began in the 1960s. Sociologists and economists were the first to contribute to the knowledge. American authors then stepped in the late 1970s to the 1990s. Starting in the 2000s, European as well as Australian colleagues took the lead in terms of number of articles published. Currently, academic research by marketing scholars is enriching this new field of inquiry on consumer behaviors and on the four traditional P's of marketing: product (and brand), price, place, and promotion.     

A Comparison of Invalidating Family Environment Characteristics Between University Students Engaging in Self-Injurious Thoughts &; Actions and Non-Self-Injuring University Students

Individuals experiencing non-suicidal self-injurious (NSSI) thoughts only are greatly overlooked by current research. This investigation aimed at determining how three groups of university students differed in their reported quality of childhood relationships with parents, and histories of physical and sexual abuses. These groups included students experiencing only NSSI thoughts (n = 126), students engaging in NSSI actions (n = 90), and students exhibiting neither (n = 1,080). Results showed that individuals experiencing NSSI thoughts only, and those engaging in NSSI actions reported poorer relationships with parents and more physical abuse than the No NSSI group; however, NSSI thoughts and NSSI action groups had similar outcomes to one another for most variables. These findings suggest that individuals experiencing only NSSI thoughts share similar negative childhood environments associated with engagement in NSSI action and that they should be included in future research, particularly investigations aimed at identifying protective factors that could prevent them from engaging in NSSI.     

Overcoming Clientelism Through Local Participatory Institutions in Mexico: What Type of Participation?

This article addresses the relationship between institutionalized citizen participation at the municipal level and clientelism. It argues, contrary to what the literature has suggested, that the institutionalization of local citizen participation does not necessarily lead to the erosion of clientelism. Drawing on a comparative case study of participatory experiences in two Mexican municipalities, León and Nezahualcóyotl, this study argues that participation does matter, but that not all types of participation have the same effect on state‐society relations. Institutional design is important in assessing the significance of popular participation in defining the relationship between the state and its citizens, but informal practices are even more important determinants of citizens' level of autonomy in institutionalized participatory mechanisms. This level of autonomy, in turn, determines the potential for such local institutions to become a means to overcome clientelism as the mechanism traditionally characterizing state‐society relationships in Mexico.     

人格权与民法典——人格权的概念和范围

《法国民法典》中的人格权制度出现于二十世纪七十年代。本文作者介绍了《法国民法典》中现有的人格权家族,并构建了理想的人格权框架。作者认为,人格权是一项民事权利而不是一项基本权利,是一项法律赋予人的权利,而不是法律规定的制度。     

Validated method for the simultaneous determination of Delta9-THC and Delta9-THC-COOH in oral fluid, urine and whole blood using solid-phase extraction and liquid chromatography-mass spectrometry with electrospray ionization

A fully validated, sensitive and specific method for the extraction and quantification of Delta(9)-tetrahydrocannabinol (THC) and 11-nor-9-carboxy-Delta(9)-THC (THC-COOH) and for the detection of 11-hydroxy-Delta(9)-THC (11-OH THC) in oral fluid, urine and whole blood is presented. Solid-phase extraction and liquid chromatography-mass spectrometry (LC-MS) technique were used, with electrospray ionization. Three ions were monitored for THC and THC-COOH and two for 11-OH THC. The compounds were quantified by selected ion recording of m/z 315.31, 329.18 and 343.16 for THC, 11-OH THC and THC-COOH, respectively, and m/z 318.27 and 346.26 for the deuterated internal standards, THC-d(3) and THC-COOH-d(3), respectively. The method proved to be precise for THC and THC-COOH both in terms of intra-day and inter-day analysis, with intra-day coefficients of variation (CV) less than 6.3, 6.6 and 6.5% for THC in saliva, urine and blood, respectively, and 6.8 and 7.7% for THC-COOH in urine and blood, respectively. Day-to-day CVs were less than 3.5, 4.9 and 11.3% for THC in saliva, urine and blood, respectively, and 6.2 and 6.4% for THC-COOH in urine and blood, respectively. Limits of detection (LOD) were 2 ng/mL for THC in oral fluid and 0.5 ng/mL for THC and THC-COOH and 20 ng/mL for 11-OH THC, in urine and blood. Calibration curves showed a linear relationship for THC and THC-COOH in all samples (r(2)>0.999) within the range investigated. The procedure presented here has high specificity, selectivity and sensitivity. It can be regarded as an alternative method to GC-MS for the confirmation of positive immunoassay test results, and can be used as a suitable analytical tool for the quantification of THC and THC-COOH in oral fluid, urine and/or blood samples.