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Forensic value of 14 novel STRs on the human Y chromosome 总被引:29,自引:0,他引:29
Redd AJ Agellon AB Kearney VA Contreras VA Karafet T Park H de Knijff P Butler JM Hammer MF 《Forensic science international》2002,130(2-3):97-111
We identified and characterized 14 novel short-tandem-repeats (STRs) on the Y chromosome and typed them in two samples, a globally diverse panel of 73 cell lines, and 148 individuals from a European-American population. These Y-STRs include eight tetranucleotide repeats (DYS449, DYS453, DYS454, DYS455, DYS456, DYS458, DYS459, and DYS464), five pentanucleotide repeats (DYS446, DYS447, DYS450, DYS452, and DYS463), and one hexanucleotide repeat (DYS448). Sequence data were obtained to designate a repeat number nomenclature. The gene diversities of an additional 22 Y-STRs, including the most commonly used in forensic databases, were directly compared in the cell line DNAs. Six of the 10 most polymorphic markers include the newly identified Y-STRs. Furthermore, these novel Y-STRs greatly improved the resolution of paternal lineages, above the level obtained with commonly used Y-STRs, in the European-American population. 相似文献
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As recently as five years ago, doctors thought they had a pretty clear picture of what causes a heart attack. They saw it as a plumbing problem: too much fat in the diet builds up in the blood vessels that feed the heart, creating stoppages that starve the heart of oxygen. It was an elegant model and one that patients could understand. But it's not that simple. Cholesterol, it turns out, is just the starting point of a cascade of interlocking events. Underlying the new research presented at the American Heart Association meeting last week was a clear message: this isn't your father's heart disease anymore. 相似文献
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Rich Gilman E. Scott Huebner Lili Tian Nansook Park Jenny O’Byrne Miriam Schiff Dina Sverko Heather Langknecht 《Journal of youth and adolescence》2008,37(2):142-154
Although numerous cross-national studies have assessed life satisfaction among adults, similar studies using adolescent samples
have been rare. To address this shortage of research, a total of 1338 youth adolescents from two individualistic nations (Ireland,
USA) and two collectivistic nations (China, South Korea) were administered the Multidimensional Students’ Life Satisfaction Scale (MSLSS: Huebner, 1994) to assesses general life satisfaction and satisfaction with family, friends, school, self, and living environment. Responses
were analyzed to assess potential cross-national differences in (a) mean levels of life satisfaction, and (b) response styles,
specifically acquiescence and extreme responding. Mean scores revealed positive ratings by adolescents from all four nations
across all domains, with the exceptions of satisfaction with school experiences (Ireland, South Korean, USA), living environment
(China, South Korea), self (South Korea), and general life satisfaction (South Korea). Results also revealed significant response
style differences across all MSLSS domains. Significant gender and gender-by-nation effects were observed for both mean score
and response style differences, although the effect sizes were small. The implications of these findings were discussed, particularly
with respect to “individualistic” vs. “collectivistic” cultural differences.
Rich Gilman is Associate Professor in the Department of Educational and Counseling Psychology at the University of Kentucky.
His research interests include positive well-being among youth, perfectionism, and socially ostracized adolescents.
Scott Huebner is Professor in the Department of Psychology at the University of South Carolina. His research interests involve
the conceptualization, measurement, and implications of positive psychological well-being constructs among youth. He is a
fellow of Division 16 of the APA and the International Society for Quality of Life Studies.
Lili Tian is Associate Professor at South China Normal University. She received her Ph.D. in psychology from Beijing Normal
University. Her major research interests include adolescent's school well-being, acculturation of immigrant children and personality
assessment.
Nansook Park is Associate Professor at the University of Rhode Island. She received her Ph.D. from University of South Carolina.
Her major research interests among youth include character strengths and virtues, positive experience and life satisfaction
and how they are related to well-being, family functioning, health and education.
Jenny O’Byrne received her BA in the Department of Counselling & Psychotherapy from the Dublin Business School. Recent research
interests focus on child and adolescent development, and she recently completed her pre-clinical training in psychoanalytic
psychotherapy with the Lincoln Centre in London.
Dina Sverko is a research assistant at the University of Zagreb (Croatia). She received her Ph.D. in psychology from the University
of Triest (Italy). Her major research interests include personality assessment and health psychology.
Miriam Schiff is lecturer (equivalent to Assistant Professor) at the Hebrew University School of Social Work and Social Welfare
in Jerusalem. Her major research interests include trauma and substance use, and general mental health among adolescents in
clinic settings.
Heather Langknecht received her Ed.S. from the University of Kentucky in 2004. She currently works as a school psychologist
at Virginia Beach Public Schools (Virginia). Her primary research interests are cross-national quality of life issues among
children and youth. 相似文献
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Brandon Beomseob Park Nikolaos Frantzeskakis Jungsub Shin 《West European politics》2019,42(3):464-494
Does voters’ ability to discern who is responsible for policy outcomes affect voter turnout? Although particular institutional arrangements which influence this ability – known as clarity of responsibility – appear to affect how voters form retrospective judgements, existing literature is less informed about its role on voter turnout. This article argues that voters tend to turn out less if they cannot discern who is responsible for policy outcomes. This lack of clarity hinders the process of retrospective evaluations, makes the electoral stakes less profound, and dampens the voters’ political efficacy. Using 396 elections in 34 established democracies between 1960 and 2015, it is found that lower clarity of responsibility is associated with lower voter turnout. This study highlights the importance of clarity of responsibility, as it enhances democratic accountability, not only by encouraging retrospective voting, but also by increasing political participation. 相似文献