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Hwan Young Lee Ph.D. Na Young Kim M.S. Myung Jin Park M.S. Jeong Eun Sim B.S. Woo Ick Yang Ph.D. Kyoung‐Jin Shin Ph.D. 《Journal of forensic sciences》2010,55(6):1422-1429
Abstract: The identification of missing casualties of the Korean War (1950–1953) has been performed using mitochondrial DNA (mtDNA) profiles, but recent advances in DNA extraction techniques and approaches using smaller amplicons have significantly increased the possibility of obtaining DNA profiles from highly degraded skeletal remains. Therefore, 21 skeletal remains of Korean War victims and 24 samples from biological relatives of the supposed victims were selected based on circumstantial evidence and/or mtDNA‐matching results and were analyzed to confirm the alleged relationship. Cumulative likelihood ratios were obtained from autosomal short tandem repeat, Y‐chromosomal STR, and mtDNA‐genotyping results, and mainly confirmed the alleged relationship with values over 105. The present analysis emphasizes the value of mini‐ and Y‐STR systems as well as an efficient DNA extraction method in DNA testing for the identification of old skeletal remains. 相似文献
384.
Korean public research institutes (PRIs) are experimenting with a consortia approach for promoting public-to-private technology
transfer. This research examines the effectiveness of five regional technology transfer consortia operating in Korea from
2002 to 2006 and explores their characteristics including motivations, facilitators, barriers, and challenges. The paper reports
both quantitative and qualitative evidence. Archival and survey data were collected on the effectiveness and characteristics
of the technology transfer consortia. The proposition was supported that membership in these consortia can enhance the technology
transfer performance of participating PRIs. Reasons on how consortia increase PRI performance are discussed and four key drivers
are seen as being critical to increasing the effectiveness of consortia. Conclusions focus on lessons learned for policy makers,
PRIs, and consortia. 相似文献
385.
Hwan Young Lee Myung Jin Park Na Young Kim Jeong Eun Sim Woo Ick Yang Kyoung-Jin Shin 《Forensic Science International: Genetics Supplement Series》2010,4(5):275-280
The recovery of DNA data from old skeletal remains is often difficult due to degraded and very low yield of extracted DNA and the presence of PCR inhibitors. Herein, we compared several silica-based DNA extraction methods from artificially degraded DNA, DNA with PCR inhibitors and DNA from old skeletal remains using quantitative real-time PCR. We present a modified large-scale silica-based extraction combined with complete demineralization, that enables maximum DNA recovery and efficient elimination of PCR inhibitors. This is performed with high concentration of EDTA solution for demineralization of bone powder followed by QIAamp® spin columns and buffers from the QIAquick® PCR purification kit. We have successfully used this modified technique to perform STR analysis for 55-year-old skeletal remains. The results of this study will contribute to solve the forensic cases dealing with skeletal remains. 相似文献
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387.
Ju Yeon Park 《Legislative Studies Quarterly》2017,42(1):3-31
In principle, committees hold hearings to gather and provide information to their principals, but some hearings are characterized as political showcases. This article investigates conditions that moderate committee members' incentives to hold an informative hearing by presenting a game‐theoretic model and a lab experiment. Specifically, it studies when committees hold hearings and which types of hearing they hold by varying policy preferences of committee members and the principal and political gains from posturing. Findings provide new insights to how preferences and power distribution affect individuals' incentives to be informed when they make decisions as members of a committee in many contexts. 相似文献
388.
Christopher A. Fischer M.D. Mace Beckson M.D. Park Dietz M.D. M.P.H. Ph.D. 《Journal of forensic sciences》2017,62(3):822-826
Factitious disorder involves the conscious simulation of psychological or physiological symptoms of illness, for the purpose of fulfilling the unconscious desire to be taken care of or to assume the “sick role.” Typically patients with factitious disorder simulate conditions that are designed to arouse feelings of empathy in care providers with the intention to engage them in caretaking. However, patients might also simulate conditions that arouse revulsion or rejection and still meet full diagnostic criteria for factitious disorder. In this case report, we present a patient who fabricated an elaborate history of being a sexually sadistic serial killer with homicidal ideation with the intention of obtaining personal attention, nurturance, and empathy from his psychotherapist. However, given the nature of his feigned condition, the patient frightened the very person whom he sought to engage in caretaking. 相似文献
389.
The increasing suicide rate in South Korea in recent decades was found to be associated with measures of social integration/regulation (birth and divorce rates). 相似文献
390.