Post-mortem changes in skeletal muscle protease and creatine phosphokinase activity — A possible marker for determination of time of death

The pattern of change in activity of two enzymes in rat skeletal muscle during body storage after death has been determined. Myofibrillar protease activity was found to increase linearly with time of storage post mortem at room temperature but not at 4 °C. In contrast, creatine phosphokinase activity declines linearly with time, and again storage at 4 °C prevented the change in enzyme activity. Starvation of animals for 5 days or forced exercise prior to death did not markedly alter the rate of change in activity of the two enzymes, although creatine phosphokinase specific activity at time of death was higher in the starved and exercised rats as compared to control animals. A plot of the logarithm of protease/creatine phosphokinase specific activities ratio versus time post mortem yields a linear curve at room temperature. These observations offer a potential method for estimating time of death.     

Privacy, Efficiency, and the Equality of Men and Women: A Revisionist View of Sex Discrimination in Employment

The Supreme Court's decision in City of Los Angeles Department of Water and Power v. Manhart has engendered a considerable debate, much of which has appeared in the pages of this Journal. Defenders of the Manhart decision take its critics to task for failure to appreciate the place of that decision in the overall jurisprudence of employment discrimination. In this article, the authors challenge the underlying conception of the law of sex discrimination that is said to dictate the result in Manhart. Far from erecting a per se rule against all sex classifications, the Civil Rights Act of 1964 is shown to recognize both the relevance of prevalent social norms about sex differences and the legitimacy of certain interests of employers as limited justifications for the maintenance of sex-conscious lines in some circumstances, a recognition that contrasts sharply with the statute's categorical prohibition on racial classifications. It follows from this discussion that Manhart's outcome was not ordained by the ethos of the laws against sex discrimination.     

Expertise and Bias in Political Communication Networks

Citizens minimize information costs by obtaining political guidance from others who have already assumed the costs of acquiring and processing political information. A problem occurs because ideal informants, typically characterized by the joint presence of political expertise and shared viewpoints, are frequently unavailable or rare within the groups where individuals are located. Hence, individuals must often look beyond their own group boundaries to find such informants. The problem is that obtaining information from individuals located beyond their own groups produces additional costs. Moreover, the availability of ideal informants varies across groups and settings, with the potential to produce (1) context‐dependent patterns of informant centrality, which in turn generate (2) varying levels of polarization among groups and (3) biases in favor of some groups at the expense of others. The article's analysis is based on a series of small‐group experiments, with aggregate implications addressed using a simple agent‐based model.     

Shot Through the Heart—Firepower and Potential Lethality of Air Weapons

Although certain air weapons attain muzzle velocities comparable to some firearms, their successful use for committing suicide is rarely seen. Herein, we report a case of a young female died shortly after urgent admission to the hospital with penetrating gunshot wound to the chest. The autopsy revealed perforation of the pericardium and two perforative defects to the right heart ventricle. Injury was inflicted by a 0.177 caliber pellet, fired from an air rifle found near her body. Investigation ruled the death as suicide. The used air rifle fired the pellet with the energy density of 1.9 J/mm², substantially above the threshold for inflicting injury. The pellet penetrated through two layers of cotton fabric and several layers of tissue to inflict fatal injury to the heart. In addition, we provide an insight into the wounding potential of air weapons, which illustrates the need for greater caution in handling those devices.     

Power in the Age of Datafication: Exploring China’s Global Data Power

Journal of Chinese Political Science - Anxieties about China’s growing data power have begun to drive geopolitical and technological competition. Yet, the size of Chinese data power is...