HPLC-ESI-MS/MS determination of zuclopenthixol in a fatal intoxication during psychiatric therapy.

The first non-suicidal fatality due to intramuscular administration of Cisordinol (zuclopenthixol, ZPT) is described. A new, rapid, and sensitive method for the determination of ZPT in postmortem specimens has been developed. High performance liquid chromatography electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS) was employed for drug confirmation and quantitation. Sample clean up was performed using a simple liquid-liquid extraction procedure. The postmortem concentration of ZPT in heart blood was 0.68 microg/ml. Furthermore, zotepine, carbamazepine, and chlorprotixene were detected in body fluids. The proposed method enables the unambiguous identification and quantitation of ZPT and other neuroleptic drugs in clinical and forensic specimens.     

Political Reinforcement: How Rising Inequality Curbs Manifested Welfare Generosity

We propose a political reinforcement hypothesis, suggesting that rising inequality moves party politics on welfare state issues to the right, strengthening rather than modifying the impact of inequality. We model policy platforms by incorporating ideology and opportunism of party members and interests and sympathies of voters. If welfare spending is a normal good within income classes, a majority of voters moves rightward when inequality increases. As a response, the left, in particular, shift their welfare policy platform toward less generosity. We find support for our arguments using data on the welfare policy platforms of political parties in 22 OECD countries.     

National Constitutional Jurisprudence in a Post‐National Europe: The ESM Ruling of the German Federal Constitutional Court and the Disavowal of Conflict

In its pending decision on the constitutionality of the European Stability Mechanism and Fiscal Compact, the German Federal Constitutional Court (FCC) has recently ruled on several applications for temporary injunctions against the transposition of these instruments. The problem of democratic self‐determination under the constraints of monetary integration has been a main concern in the ruling. Yet, the democracy‐safeguards the FCC has prescribed are parochial in not considering their impact on other EU Member States, and the Court's view of autonomy is skewed towards the issue of spending. Both concepts are at odds with the current level of transnational interdependence, which the FCC as relay to ‘integration by stealth’ has facilitated during two decades of EU‐jurisprudence. Constitutional jurisdiction should acknowledge its role in this state of affairs and fortify its effort in building judicial networks of deliberative exchange to overcome outworn parochialisms.     

Russia and south Africa in the nineties

Extracts from a paper presented at the Russian Academy of Sciences, Institute of Universal History, Centre for African Studies and at the Moscow State University, Institute of Asian and African Studies, Centre for African History.     

A study of amnesia in homicide cases and forensic psychiatric experts' examination of such claims

About one third of defendants in homicide cases claim amnesia during the time of their alleged act. Examining the authenticity of claimed amnesia is a special challenge for forensic experts. Because the experts' conclusions have legal implications, it is useful to study the characteristics of defendants who claim amnesia regarding a homicidal act and how forensic experts assess these defendants' claims. The forensic psychiatric reports from 2001 to 2007 on 102 Norwegian defendants charged with homicide were assessed quantitatively with a structured rating form. Due to multiple comparisons p of .003 was chosen. Twenty-six defendants claimed partial and 17 claimed total amnesia. No significant differences in the characteristics of the defendants were found between the partial, total, and no amnesia claiming groups. Claims of partial or total amnesia did not change the procedures and content of the forensic experts' examination. A memory test was applied in only one case. Despite the seriousness of the crime and the difficulty of assessing amnesia, the experts did not apply psychological testing of memory function or appropriate tests of possible malingering. Guidelines or standardized procedures for evaluation of defendants who claim amnesia should be developed. This could eventually contribute to more reliable and valid evaluations by forensic experts and increase the probability of just court outcomes.     

Richard Rorty und die Reanimation des Pragmatismus im „Zeitalter der Komposition“

In recent years, pragmatism is experiencing a renaissance. Classic authors like George Herbert Mead, William James or John Dewey are entering sociological discussions and neopragmatistic approaches as the actor-network theory or the sociology of conventions are gaining influence. But under what social circumstances is the reanimation of pragmatism happening and what analytical use do pragmatistic tools have? In order to answer this research question the article develops a general model of social order that distinguishes between the states of collision, composition, institution and deconstruction. On this basis, a social diagnosis is articulated, making the currency of the pragmatistic vocabulary understandable. It appears that pragmatism is focused on experimental, creative and hybrid processes of becoming that are typical for the current age of composition. With the help of the often neglected Richard Rorty, the added value of a pragmatistically-informed sociology is shown in an exemplary manner. Therefore, Rorty is introduced as an integrating figure of pragmatistic ideas, from which important impulses for a Darwinian, relational, symmetrical and ironically-engaged sociology could exert.