Managing generic competition and patent strategies in the pharmaceutical industry

Legal context: The income streams of originating pharmaceutical manufacturersare under pressure as never before, from increasing R&Dcosts, regulatory pressures, and competition from generic manufacturers.This article examines the various strategies which originatingpharmaceutical manufacturers have adopted in response to thesethreats. Key points: The authors consider various strategies, including SupplementaryProtection Certificates, life-cycle management (‘evergreening’),second pharmaceutical use claims, trade marks, and the use ofdata exclusivity and interim injunctions, in order to prolongthe protection given to existing products, and to manage competitionfrom generic manufacturers. Practical significance: The authors also include two real-life case studies in orderto illustrate the practical applications of the strategies discussedin the article.     

Effects of Public Opinion and Political System Characteristics on State Policy Outputs

Rather than competing with socioeconomic variables as directdeterminants of state policy, political system characteristicsmay operate as mediating factors that either facilitate or impedethe translation of constituency preferences into policy. Inthis study, the state opinion liberalism index presented byGerald Wright, Robert Erikson, and John Mclver is incorporatedin multiplicative regression models as a measure of citizenpreferences to address this theoretical reformulation. Althoughpervasive empirical corroboration is not found for the reconceptualizedrole for political variables, political system characteristicsdo demonstrate significant effects on state policy. In addition,suggesting that public officials responddirectly to citizenpreferences, evidence ispresentedon democratic representationwithin the states.     

The Consequences of Gentrification for Racial Change in Washington,DC

This article looks at the effects of gentrification on the racial composition and transformation of urban neighborhoods. The investigation examines Washington, DC, a city that has undergone significant and contentious racial transformation in the past few decades. To provide for a more robust analysis of how gentrification is associated with measures of racial displacement and diversity, I employ two separate quantitative measures. Using U.S. Census Bureau long form, American Community Survey, and decennial census data, I compare tract-level changes in racial evenness and displacement between gentrifying and nongentrifying areas from 1990 to 2010. The findings suggest that gentrification is associated with the displacement of blacks, but this racial turnover is not consistently associated with greater levels of racial and ethnic diversity compared with nongentrifying neighborhoods.